Pseudomonas Genome Project


Pseudonomas aeruginosa
Cystic Fibrosis
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Graphic from
James A. Sullivan,
CELLS alive!

 

Pseudomonas aeruginosa is a versatile Gram-negative bacterium that grows in soil, marshes, and coastal marine habitats, as well as on plant and animal tissues. People with cystic fibrosis , burn victims, individuals with cancer, and patients requiring extensive stays in intensive care units are particularly at risk of disease resulting from P. aeruginosa infection.

The complete sequence of the genome of P. aeruginosa strain PAO1 was determined in a collaboration among the Cystic Fibrosis Foundation, the University of Washington Genome Center and PathoGenesis Corporation. The largest bacterial genome sequenced to date, the 6.3-Mbp genome contains 5570 predicted genes. Genome annotation was carried out by PathoGenesis scientists and by scientists in the Pseudomonas Community Annotation Project (PseudoCAP). This work was published in Nature , Stover et al. 406:959-964 (2000).


Click a region on the map below to view a more detailed
linear map of that region of the genome.
Clickable Image Map of the P. aeruginosa genome