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© 1995 Academic Electronic Press
The publication is free to copy and distribute for non-commercial personal use with written permission of Academic Electronic Press. Any modifications of the original document are strictly prohibited. No fee is charged for using, copying or distributing. A written permission for distribution and copying can be obtained via Internet at the adress . The number of copies has to be announced.

© 1995 Computing Centre, Slovak Academy of Sciences, Slovakia online
The book is also available in Internet. HTML format at URL =
ISBN 80--967366--1--2

Information on ''INFLAMMATION AND FEVER'':

Inflammation is a manifestation of the body's response to tissue damage and infection. The discovery of the detailed processes of inflammation has revealed a close relationship between inflammation and the immune response.

Inflammation is a complex stereotypical reaction involving a number of cellular and molecular components and important changes in the physiological systems as well. The result of each inflammatory reaction may be beneficial (defence the body against agents deranging its homeostasis) or harmful (damage to surrounding tissues). Therefore the basic information about this process is necessary for undergraduate and postgraduate students, clinicians, pathologists and other specialists in medicine, imunology, and molecular biology to whom the book is devoted.

It provides a short but comprehensive introduction to cellular and molecular aspects of exudation and sweling, cells participating in inflammation, mechanisms of their accumulation in inflamed tissue through the adhesive interaction between leukocytes and endothelial cells within the microcirculation, products of the complex plasma enzyme systems (the complement, kinin, haemocoagulation and fibrinolytic pathways), categories of inflammation mediated by the immune system and the role of fever.

The special chapters are focused on the regulatory functions of the adhesion molecules and inflammatory mediators, namely histamine and serotonin, bioactive lipids, proinflammatory and anti-inflammatory cytokines, chemotactic factors and the acute phase reactants. Regulation and control of body temperature and pathogenesis of fever are also discussed. Starting from the basic knowledges, the book offers survey of current concepts from both research and clinical points of view.
113 pages, 14 tables, 6 figures.

Published by:
Viera ’Stvrtinová, assistent professor of Internal Medicine,
Ján Jakubovský, associated professor of Pathology,
Ivan Hulín, professor of Pathophysiology
--- all in the Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.

The book ''Inflammation and fever'' is available in Internet as:
1. PostScript file at URL =
2. HTML format at URL =

next up previous contents
Next: Contents

Peter Slavkovsky
Tue Jun 27 14:33:11 MET DST 1995