The Herbal Abstract Page:
(Herbal Medicine via Medline)
 

Offering hundreds of Medline and other abstracts dealing with herbal and traditional Chinese medical therapies.  Veterinary articles highlighted in green text. *** This page is an extensive list. 
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General

Arch Environ Health 2002 May-Jun;57(3):229-31 Medicinal herbs: a potential source of toxic metal exposure for man and animals in India. Dwivedi SK, Dey S.

Toxicology 2002 Dec 27;181-182:577-80 Renal interstitial fibrosis and urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). Nortier JL, Vanherweghem JL.

Ann Intern Med 2002 Dec 17;137(12):939-46 Treatment of the common cold with unrefined echinacea. A randomized, double-blind, placebo-controlled trial. Barrett BP, Brown RL, Locken K, Maberry R, Bobula JA, D'Alessio D.

Vet Clin North Am Small Anim Pract 2002 Mar;32(2):367-82 Selected herbal hazards.  Means C.

Wien Med Wochenschr 2002;152(7-8):183-9 Risks associated with herbal medicinal products. Ernst E, Pittler MH.

Am J Health Syst Pharm 2002 Feb 15;59(4):339-47 Update on natural product--drug interactions. Scott GN, Elmer GW.

Planta Med 2002 Feb;68(2):178-180 The Influence of the Harvest Cut Height on the Quality of the Herbal Drugs Melissae folium and Melissae herba. Mrlianova M, Tekel'ova D, Felklova M, Reinohl V, Toth J.

Harefuah 2001 Aug;140(8):780-3, 805 [The safety of herbal medicines in the psychiatric practice] [Article in Hebrew] Boniel T, Dannon P.

Drugs 2001;61(15):2163-75 Interactions between herbal medicines and prescribed drugs: a systematic review. Izzo AA, Ernst E.

BMC Complement Altern Med 2001;1(1):5 Systematic reviews of complementary therapies - an annotated bibliography. Part 2: Herbal medicine. Linde K, ter Riet G, Hondras M, Vickers A, Saller R, Melchart D.

JAMA 2001 Jul 11;286(2):208-216 Herbal Medicines and Perioperative Care. Ang-Lee MK, Moss J, Yuan CS.

Acad Med 2001 76: 238-247 The importance of using scientific principles in the development of medicinal agents from plants. Talalay P, Talalay P

Emerg Med Clin North Am 2000 Nov;18(4):709-22 Herbal and alternative medicine. Nelson L, Perrone J

Br J Dermatol 2000 Nov;143(5):923-9 Adverse effects of herbal drugs in dermatology. Ernst E

Thorax 2000 Nov;55(11):925-9 Herbal medicines for asthma: a systematic review. Huntley A, Ernst E

J Clin Psychiatry 2000 Nov;61(11):815-20 Adverse neuropsychiatric reactions to herbal and over-the-counter "antidepressants". Pies R

N Z Med J 2000 Jul 28;113(1114):315-7 "Herbal Ecstasy": a case series of adverse reactions. Yates KM, O'Connor A, Horsley CA.

AANA J 2000 Jun;68(3):217-20 Hemorrhage after the preoperative use of complementary and alternative medicines. Norred CL, Finlayson CA

Biochem Pharmacol 2000 Feb 1;59(3):211-9 Medicinal herbs: drugs or dietary supplements? Chang J

Lancet 2000 Jan 8;355(9198):134-8 Herb-drug interactions. Fugh-Berman A

J Am Med Womens Assoc 1999 Fall;54(4):191-2 Dietary supplement-drug interactions. Smolinske SC

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Med J Aust 1999 Dec 6-20;171(11-12):604-8 The effectiveness of popular, non-prescription weight loss supplements. Egger G, Cameron-Smith D, Stanton R

Rev Med Brux. 1999 Feb;20(1):9-14. Review. French. [Herbal remedies and nephrotoxicity]. Nortier J, Depierreux M, Vanherweghem JL.

Br J Clin Pharmacol 1999 Aug;48(2):262-4 The treatment of eczema with Chinese herbs: a systematic review of randomized clinical trials. Armstrong NC, Ernst E

Altern Ther Health Med 1999 Jul;5(4):40-9 Assessing the risks and benefits of herbal medicine: an overview of scientific evidence. Barrett B, Kiefer D, Rabago D

Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1999 May;15(5):297-301 Rapid progression of parkinsonism associated with an increase of blood manganese. Kao HJ, Chen WH, Liu JS

Am Fam Physician 1999 Mar 1;59(5):1239-45 Herbal remedies: adverse effects and drug interactions. Cupp MJ

Arch Intern Med 1998 Nov 9;158(20):2192-9 Herbs as medicines. Winslow LC, Kroll DJ

N Engl J Med 1998 Sep 17;339(12):785-91 Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. DiPaola RS, Zhang H, Lambert GH, Meeker R, Licitra E, Rafi MM, Zhu BT, Spaulding H, Goodin S, Toledano MB, Hait WN, Gallo MA

Postgrad Med 1998 Jul;104(1):91-5, 99-100 The dangers of using herbs. What your patients need to know. Borins M

Br J Clin Pharmacol 1998 May;45(5):496-500 Different standards for reporting ADRs to herbal remedies and conventional OTC medicines: face-to-face interviews with 515 users of herbal remedies. Barnes J, Mills SY, Abbot NC, Willoughby M, Ernst E

Am J Med 1998 Feb;104(2):170-8 Harmless herbs? A review of the recent literature. Ernst E

Drug Saf 1997 Oct;17(4):209-15 Monitoring the safety of herbal medicines. Chan TY

Acad Emerg Med 1997 Mar;4(3):209-13 Herbal preparation use among urban emergency department patients. Hung OL, Shih RD, Chiang WK, Nelson LS, Hoffman RS, Goldfrank LR

Hum Exp Toxicol 1996 Jan;15(1):5-12 Usage and adverse effects of Chinese herbal medicines. Chan TY, Critchley JA

Teratog Carcinog Mutagen 1996;16(2):125-38 An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. Basaran AA, Yu TW, Plewa MJ, Anderson D

Vet Hum Toxicol 1995 Dec;37(6):562-6 Possible association of liver damage with the use of Chinese herbal medicine for skin disease. Perharic L, Shaw D, Leon C, De Smet PA, Murray VS

South Med J 1995 Sep;88(9):911-3 Herbs and HIV: the health food industry's answer. Phillips LG, Nichols MH, King WD

Am J Health Syst Pharm 2000 Jul 1;57(13):1221-7; quiz 1228-30 Potential interactions between alternative therapies and warfarin. Heck AM, DeWitt BA, Lukes AL.

Hum Exp Toxicol 1995 May;14(5):434-6 Poisoning due to Chinese proprietary medicines. Chan TY, Lee KK, Chan AY, Critchley JA

Chung Kuo Chung Yao Tsa Chih 1995 Feb;20(2):70-2, 126 [Identification on the botanical origin of xueshangyizhihao produced in Shaanxi, Gansu, Sichuan Provinces and Ningxia Hui Autonomous Region]. [Article in Chinese] Fu L, Bao X, Zhang Z

Gut 1995 Jan;36(1):146-7 Hepatitis induced by traditional Chinese herbs; possible toxic components. Kane JA, Kane SP, Jain S

J Trop Med Hyg 1994 Dec;97(6):371-4 Herbal poisoning caused by adulterants or erroneous substitutes. But PP

Drug Saf 1994 Oct;11(4):284-94 Toxicological problems resulting from exposure to traditional remedies and food supplements. Perharic L, Shaw D, Colbridge M, House I, Leon C, Murray V

Emerg Med Clin North Am 1994 May;12(2):483-510 Hazards of nonprescription medications. Cetaruk EW, Aaron CK

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Ann Trop Paediatr 1992;12(1):31-6 The use of herbal remedies in Jamaica. Michie CA

Med J Aust 1992 Oct 5;157(7):484-6 Adverse reaction to a Chinese herbal remedy. Gorey JD, Wahlqvist ML, Boyce NW

J Trop Med Hyg 1992 Aug;95(4):296-8 Hospital admissions due to adverse reactions to Chinese herbal medicines. Chan TY, Chan AY, Critchley JA

Arch Intern Med 1991 Nov;151(11):2281-8 The use of medicinal herbs by human immunodeficiency virus-infected patients. Kassler WJ, Blanc P, Greenblatt R

Planta Med 1991 Jun;57(3):237-41 Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay. Zani F, Massimo G, Benvenuti S, Bianchi A, Albasini A, Melegari M, Vampa G, Bellotti A, Mazza P

Schweiz Med Wochenschr 1990 Apr 21;120(16):581-8 [Placebo action and alternative medicine]. [Article in German] Fahrlander H, Truog P

J Anim Sci 1990 Mar;68(3):892-904 Natural plant toxicants in milk: a review. Panter KE, James LF

Rev Environ Contam Toxicol 1990;113:47-137 Natural pesticides and bioactive components in foods. Beier RC

Arch Environ Health 1987 May-Jun;42(3):133-6 Toxic effects of herbal teas. Ridker PM

J Natl Cancer Inst 1978 Mar;60(3):683-6 Carcinogenicity of some folk medicinal herbs in rats. Kapadia GJ, Chung EB, Ghosh B, Shukla YN, Basak SP, Morton JF, Pradhan SN

J Natl Cancer Inst 1976 Jul;57(1):207-9 Carcinogenicity of Camellia sinensis (tea) and some tannin-containing folk medicinal herbs administered subcutaneously in rats. Kapadia GJ, Paul BD, Chung EB, Ghosh B, Pradhan SN

S Afr Med J 1975 Nov 1;49(46):1907-10 Acute renal failure in Indian and Black patients. Seedat YK, North-Coombes D, Sewdarsen M

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Adulterants, contaminants, and misidentified plant material in herbal therapeutic agents:

Health Canada warns public not to use Hua Fo [Ginseng]. Health Canada, February 15, 2002

Clin Tech Small Anim Pract 2002 Feb;17(1):6-18 Herbal medicine: potential for intoxication and interactions with conventional drugs. Poppenga RH.

Am J Nephrol 2001 Nov-Dec;21(6):441-8 Rapidly progressive interstitial renal fibrosis associated with chinese herbal medications. Chang CH, Wang YM, Yang AH, Chiang SS.

Br J Dermatol 2000 Nov;143(5):923-9 Adverse effects of herbal drugs in dermatology. Ernst E

N Engl J Med 2000 Jun 8;342(23):1686-1692 Urothelial Carcinoma Associated with the Use of a Chinese Herb (Aristolochia fangchi). Nortier JL, Martinez MC, Schmeiser HH, Arlt VM, Bieler CA, Petein M, Depierreux MF, De Pauw L, Abramowicz D, Vereerstraeten P, Vanherweghem JL

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Sci Total Environ 2000 Feb 28;247(1):51-6 Chromium levels in spices and aromatic herbs. Garcia E, Cabrera C, Lorenzo ML, Lopez MC

Lancet 1999 Aug 7;354(9177):481-2 Nephropathy caused by Chinese herbs in the UK. Lord GM, Tagore R, Cook T, Gower P, Pusey CD

Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1999 May;15(5):297-301 Rapid progression of parkinsonism associated with an increase of blood manganese. Kao HJ, Chen WH, Liu JS

Acta Neurol Scand 1998 Dec;98(6):461-5 Chronic inorganic mercury induced peripheral neuropathy. Chu CC, Huang CC, Ryu SJ, Wu TN

Eur J Epidemiol 1998 Apr;14(3):269-74 Molds and mycotoxins in herb tea and medicinal plants. Halt M

Pharm World Sci 1998 Feb;20(1):43-4 Acute hepatitis in a patient using a Chinese herbal tea--a case report. Levi M, Guchelaar HJ, Woerdenbag HJ, Zhu YP

Nephrologie 1998;19(1):15-20 [End-stage renal insufficiency associated with Chinese herbal consumption in France]. [Article in French] Stengel B, Jones E

Arch Intern Med 1997 Sep 22;157(17):2007-9 Mandrake toxicity. A case of mistaken identity. Frasca T, Brett AS, Yoo SD

Ned Tijdschr Geneeskd. 1997 Aug 16;141(33):1626. Dutch.[Dexamethasone in a non-registered ointment from the Far East]. de Smet PA, Wagenaar HW, Smeets OS.

Schweiz Rundsch Med Prax 1997 May 28;86(22):952-6 [Follow-up and therapy of acute colchicine poisoning]. [Article in German] Stern N, Kupferschmidt H, Meier-Abt PJ

J Clin Pharmacol 1997 Apr;37(4):344-50 Adulteration by synthetic therapeutic substances of traditional Chinese medicines in Taiwan. Huang WF, Wen KC, Hsiao ML

J Pharm Belg 1997 Jan-Feb;52(1):7-27 Belgian (Chinese herb) nephropathy: why? Violon C

Kidney Int 1997 Jan;51(1):288-93 Proximal tubular injury in Chinese herbs nephropathy: monitoring by neutral endopeptidase enzymuria. Nortier JL, Deschodt-Lanckman MM, Simon S, Thielemans NO, de Prez EG, Depierreux MF, Tielemans CL, Richard C, Lauwerys RR, Bernard AM, Vanherweghem JL

Am J Gastroenterol 1996 Jul;91(7):1436-8 Acute hepatitis associated with the use of a Chinese herbal product, ma-huang. Nadir A, Agrawal S, King PD, Marshall JB

Arch Intern Med 1996 Apr 22;156(8):899-903 The clinical spectrum of Jin Bu Huan toxicity. Horowitz RS, Feldhaus K, Dart RC, Stermitz FR, Beck JJ.

Vet Hum Toxicol 1995 Apr;37(2):156-7 Anticholinergic poisoning due to Chinese herbal medicines .Chan TY

J Trop Med Hyg. 1994 Dec;97(6):371-4. Herbal poisoning caused by adulterants or erroneous substitutes. But PP.

Am J Kidney Dis 1994 Aug;24(2):172-80 Pathologic aspects of a newly described nephropathy related to the prolonged use of Chinese herbs. Depierreux M, Van Damme B, Vanden Houte K, Vanherweghem JL

JAMA 1994 Mar 23-30;271(12):932-4 Lead poisoning due to hai ge fen. The porphyrin content of individual erythrocytes. Markowitz SB, Nunez CM, Klitzman S, Munshi AA, Kim WS, Eisinger J, Landrigan PJ

Postgrad Med J 1994 Feb;70(820):113-4 Indian herbal remedies for diabetes as a cause of lead poisoning. Keen RW, Deacon AC, Delves HT, Moreton JA, Frost PG

Bull Mem Acad R Med Belg 1994;149(1-2):128-35; discussion 135-40 [A new form of nephropathy secondary to the absorption of Chinese herbs]. [Article in French] Vanherweghem JL

Lancet 1993 Feb 13;341(8842):387-91 Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Vanherweghem JL, Depierreux M, Tielemans C, Abramowicz D, Dratwa M, Jadoul M, Richard C, Vandervelde D, Verbeelen D, Vanhaelen-Fastre R, et al

Med J Aust 1992 Dec 7-21;157(11-12):835-6 Lead poisoning from Indian herbal medicine. Dunbabin DW, Tallis GA, Popplewell PY, Lee RA

Vet Hum Toxicol 1992 Jun;34(3):235-8 Chinese patent medicine as a potential source of mercury poisoning. Kang-Yum E, Oransky SH

Gastroenterol Clin Biol 1992;16(1):92-5 [Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases]. [Article in French] Pauwels A, Thierman-Duffaud D, Azanowsky JM, Loiseau D, Biour M, Levy VG

Ann Acad Med Singapore 1986 Jan;15(1):118-21 Drug eruptions from phenylbutazone in Jamu. Giam YC, Tham SN, Tan T, Lim A

Appl Environ Microbiol 1978 Aug;36(2):252-6 Fungal contamination and mycotoxin detection of powdered herbal drugs. Hitokoto H, Morozumi S, Wauke T, Sakai S, Kurata H

Med J Aust 1975 Sep 13;2(11):424-8 Arsenic poisoning from anti-asthmatic herbal preparations. Tay CH, Seah CS

JAMA 1975 Jan 27;231(4):352-5 Agranulocytosis caused by Chinese herbal medicines. Dangers of medications containing aminopyrine and phenylbutazone. Ries CA, Sahud MA

Acetobacter xylinum (bacteria) and various unidentified yeast species – (unidentified toxins)

J Gen Intern Med 1997 Oct;12(10):643-4 Probable gastrointestinal toxicity of Kombucha tea: is this beverage healthy or harmful? Srinivasan R, Smolinske S, Greenbaum D

MMWR Morb Mortal Wkly Rep 1995 Dec 8;44(48):892-3, 899-900 Unexplained severe illness possibly associated with consumption of Kombucha tea--Iowa, 1995. No authors cited

Aconite (Monk’s Hood) – See: Aconitum spp., Ranunculaceae

Aconitum spp., Ranunculaceae -- (aconitum alkaloid toxicity)

Cardiology 1999 Oct;91(4):268-271 Bradycardia, Reversible Panconduction Defect and Syncope following Self-Medication with a Homeopathic Medicine. Guha S, Dawn B, Dutta G, Chakraborty T, Pain S

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

Hum Exp Toxicol 1995 Jun;14(6):489-93 Effects of decoctions prepared from Aconitum carmichaeli, Aconitum kusnezoffii and Tripterygium wilfordii on serum lactate dehydrogenase activity and histology of liver, kidney, heart and gonad in mice. Chan WY, Ng TB, Lu JL, Cao YX, Wang MZ, Liu WK

Korean J Ophthalmol 1994 Dec;8(2):77-82 Aconite induced myelo-optic neuropathy in a rabbit model. Suk KD, Yoon KC, Shin JP, Kim SH

Vet Hum Toxicol. 1994 Oct;36(5):452-5. Review.Aconitine poisoning due to Chinese herbal medicines: a review. Chan TY, Tomlinson B, Tse LK, Chan JC, Chan WW, Critchley JA.

Vet Hum Toxicol 1994 Aug;36(4):326-8 Aconitine poisoning: a global perspective. Chan TY

Vet Hum Toxicol. 1994 Apr;36(2):133-4. Herb-induced aconitine poisoning presenting as tetraplegia. Chan TY, Tomlinson B, Critchley JA, Cockram CS.

Aust N Z J Med 1993 Jun;23(3):268-71 Aconitine poisoning following the ingestion of Chinese herbal medicines: a report of eight cases. Chan TY, Tomlinson B, Critchley JA

Lancet 1992 Nov 21;340(8830):1254-6 Cardiotoxicity after accidental herb-induced aconite poisoning. Tai YT, But PP, Young K, Lau CP

AIDS: See HIV

Akebia spp., Lardizabalaceae

FDA bulletin, May 31, 2000, Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Alfalfa – See: Medicago sativa, Fabaceae

Allium sativa, Liliaceae

Ann Intern Med 2000 Sep 19;133(6):420-9 Garlic for treating hypercholesterolemia. A meta-analysis of randomized clinical trials. Stevinson C, Pittler MH, Ernst E

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Alocasia macrorrhiza, Araceae

Hum Exp Toxicol 1995 Sep;14(9):727-8 Neurotoxicity following the ingestion of a Chinese

Aloe vera, Asphodelaceae (Liliaceae s.l.)

Br J Gen Pract 1999 Oct;49(447):823-8 Aloe vera: a systematic review of its clinical effectiveness. Vogler BK, Ernst E

FDA Special Nutritionals Adverse Event Monitoring System (SN/AEMS) Report on Aloe

Toxicon 1997 Sep;35(9):1423-30 Cytotoxicity of a low molecular weight fraction from Aloe vera (Aloe barbadensis Miller) gel. Avila H, Rivero J, Herrera F, Fraile G.

Angelica spp., Apiaceae

Health Care Reality Check FAQ -- Dong Quai.Maida Taylor, Helen Coleman

Pharmacotherapy 1999 Jul;19(7):870-6 Potentiation of warfarin by dong quai. Page RL 2nd, Lawrence JD.

Fertil Steril 1997 Dec;68(6):981-6 Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Hirata JD, Swiersz LM, Zell B, Small R, Ettinger B.

Phytochemistry 1995 Jul;39(5):1099-101 Angelol-type coumarins from Angelica pubescence F. biserrata and their inhibitory effect on platelet aggregation. Liu JH, Xu SX, Yao XS, Kobayashi H.

Anise – See: Pimpinella anisum, Apiaceae

Arctium spp., Asteraceae(Burdock, Common burdock)

From “Indiana Plants Poisonous to Livestock and Pets” Website, Purdue University, School of Veterinary Medicine.

Aristolochia spp. Aristolochiaceae – (aristolochic acid toxicity)

Am J Nephrol 2001 Nov-Dec;21(6):441-8 Rapidly progressive interstitial renal fibrosis associated with chinese herbal medications. Chang CH, Wang YM, Yang AH, Chiang SS.

Mutat Res 2001 Jul 25;494(1-2):143-50 Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy. Arlt VM, Pfohl-Leszkowicz A, Cosyns J, Schmeiser HH.

Acta Pharmacol Sin 2000 Dec;21(12):1129-35 Long-term outcome of acute renal injury induced by Aristolochia manshuriensis Kom in rats. Qiu Q, Liu ZH, Chen HP, Yin HL, Li LS.

N Engl J Med 2000 Jun 8;342(23):1686-1692 Urothelial Carcinoma Associated with the Use of a Chinese Herb (Aristolochia fangchi). Nortier JL, Martinez MC, Schmeiser HH, Arlt VM, Bieler CA, Petein M, Depierreux MF, De Pauw L, Abramowicz D, Vereerstraeten P, Vanherweghem JL

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Clin Nephrol 2000 Apr;53(4):301-6, Chinese herb nephropathy in Japan presents adult-onset Fanconi syndrome: could different components of aristolochic acids cause a different type of Chinese herb nephropathy? Tanaka A, Nishida R, Maeda K, Sugawara A, Kuwahara T

Lancet 1999 Aug 7;354(9177):481-2 Nephropathy caused by Chinese herbs in the UK. Lord GM, Tagore R, Cook T, Gower P, Pusey CD

Pharm World Sci 1998 Feb;20(1):43-4 Acute hepatitis in a patient using a Chinese herbal tea--a case report.Levi M, Guchelaar HJ, Woerdenbag HJ, Zhu YP

Nephrologie 1998;19(1):15-20 [End-stage renal insufficiency associated with Chinese herbal consumption in France]. [Article in French] Stengel B, Jones E

J Pharm Belg 1997 Jan-Feb;52(1):7-27 Belgian (Chinese herb) nephropathy: why? Violon C

Kidney Int 1997 Jan;51(1):288-93 Proximal tubular injury in Chinese herbs nephropathy: monitoring by neutral endopeptidase enzymuria. Nortier JL, Deschodt-Lanckman MM, Simon S, Thielemans NO, de Prez EG, Depierreux MF, Tielemans CL, Richard C, Lauwerys RR, Bernard AM, Vanherweghem JL

Am J Kidney Dis 1994 Aug;24(2):172-80 Pathologic aspects of a newly described nephropathy related to the prolonged use of Chinese herbs. Depierreux M, Van Damme B, Vanden Houte K, Vanherweghem JL

Bull Mem Acad R Med Belg 1994;149(1-2):128-35; discussion 135-40.[A new form of nephropathy secondary to the absorption of Chinese herbs]. [Article in French] Vanherweghem JL

Lancet 1993 Feb 13;341(8842):387-91 Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Vanherweghem JL, Depierreux M, Tielemans C, Abramowicz D, Dratwa M, Jadoul M, Richard C, Vandervelde D, Verbeelen D, Vanhaelen-Fastre R, et al

Artemisia scoparia, Asteraceae

Paediatr Child Health 1993 Aug;29(4):292-4 An old traditional herbal remedy for neonatal jaundice with a newly identified risk. Yeung CY, Leung CS, Chen YZ

Asarum spp., Aristolochiaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Asthma

Thorax 2000 Nov;55(11):925-929 Herbal medicines for asthma: a systematic review. Huntley A, Ernst E

Atractylis gummifera, Asteraceae

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Atropa belladonna, Solanaceae

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

Bajiaolian (Chinese mayapple) – See: Dysosma pleiantha, Podophyllaceae

Bee Pollen

South Med J 1999 Nov;92(11):1095-7 Acute hepatitis after ingestion of herbs. Shad JA, Chinn CG, Brann OS

Black Cohosh – See: Cimicifuga racemosa, Ranunculaceae

Borage – See: Borago officinalis, Boraginaceae

Borago officinalis, Boraginaceae

FDA Special Nutritionals Adverse Event Monitoring System (SN/AEMS) Report on Borage

Bragantia spp.

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Burdock – See: Arctium spp. Asteraceae

Buttercup – See: Ranunculus spp., Ranunculaceae

Callilepis laureola, Asteraceae

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

S Afr Med J 1979 Feb 24;55(8):290-2 The clinical syndrome of Impila (Callilepis laureola) poisoning in children. Watson AR, Coovadia HM, Bhoola KD

Camellia sinensis (tea), Theaceae– (tannin toxicity)

J Natl Cancer Inst 1976 Jul;57(1):207-9 Carcinogenicity of Camellia sinensis (tea) and some tannin-containing folk medicinal herbs administered subcutaneously in rats. Kapadia GJ, Paul BD, Chung EB, Ghosh B, Pradhan SN

Camphor – See: Cinnamomum camphora

Caowu – See: Aconitum spp., Ranunculaceae

Celandine, common or lesser: See Chelidonium majus, Papaveraceae

Chaparral – See: Larrea tridentata, Zygophyllaceae

Chelidonium majus, Papaveraceae

Dtsch Med Wochenschr 1998 Nov 20;123(47):1410-4 [Necrotizing hepatitis after taking herbal remedies]. [Article in German] Strahl S, Ehret V, Dahm HH, Maier KP

Chenopodium graveolens, Chenopodiaceae

Gac Med Mex 1996 Jul-Aug;132(4):433-7 [Fatal poisoning caused by oil of epazote, Chenopodium graveolens] [Article in Spanish] Montoya-Cabrera MA, Escalante-Galindo P, Meckes-Fisher M, Sanchez-Vaca G, Flores-Alvarez E, Reynoso-Garcia M.

Chuanwu – See: Aconitum spp., Ranunculaceae

Chuen-Lin – See: Coptis spp., Ranunculaceae

Cimicifuga racemosa, Ranunculaceae (Black Cohosh)

Health Care Reality Check FAQ – Black Cohosh. Maida Taylor, Helen Coleman

J Clin Oncol 2001 May 15;19(10):2739-45 Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. Jacobson JS, Troxel AB, Evans J, Klaus L, Vahdat L, Kinne D, Lo KM, Moore A, Rosenman PJ, Kaufman EL, Neugut AI, Grann VR.

Cinnamomum camphora, Lauraceae(Camphor)

South Med J 93(6):596-598, 2000,Camphor hepatoxicity. Aliye Uc, MD, Warren P. Bishop, MD, and Kathleen D. Sanders, MD,

J Paediatr Child Health 1999 Feb;35(1):105-6 Camphor toxicity. Emery DP, Corban JG

Pediatr Emerg Care 1996 Aug;12(4):298-300, Unusual cause of seizure. Gouin S, Patel H

Pediatr Emerg Care 1993 Oct;9(5):292-7 Small doses, big problems: a selected review of highly toxic common medications.Liebelt EL, Shannon MW

Biochem Pharmacol 1992 Jun 9;43(11):2359-68 Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh). Bonkovsky HL, Cable EE, Cable JW, Donohue SE, White EC, Greene YJ, Lambrecht RW, Srivastava KK, Arnold WN

Am J Emerg Med 1989 Jan;7(1):41-3 Camphor ingestion. Gibson DE, Moore GP, Pfaff JA

Pediatr Clin North Am 1986 Apr;33(2):375-9 Camphor toxicity. Siegel E, Wason S

Vet Hum Toxicol 1984;26 Suppl 2:8-10, Camphor toxicity: development of a triage strategy. Geller RJ, Spyker DA, Garrettson LK, Rogol AD

Gastroenterology 1983 Feb;84(2):394-8 Chronic camphor ingestion mimicking Reye's syndrome. Jimenez JF, Brown AL, Arnold WC, Byrne WJ

Clin Toxicol 1981 Dec;18(12):1485-98 Toxicity of some essential plant oils. Clinical and experimental study. Millet Y, Jouglard J, Steinmetz MD, Tognetti P, Joanny P, Arditti J

Clematis spp., Ranunculaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Cocculus spp., Menispermaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Coltsfoot – See: Tussilago farfara, Asteraceae

Comfrey – See: Symphytum officinale, Boraginaceae

Common burdock – See: Arctium spp., Asteraceae

Coptis spp., Ranunculaceae

Vet Hum Toxicol 1994 Jun;36(3):238-40 The prevalence use and harmful potential of some Chinese herbal medicines in babies and children. Chan TY

Biol Neonate 1990;58(2):98-103 Effect of a popular Chinese herb on neonatal bilirubin protein binding. Yeung CY, Lee FT, Wong HN

Crotalaria assamica, Fabaceae– (monocrotaline toxicity)

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Am J Chin Med 1989;17(3-4):165-70 A comparative study on the hepatic toxicity and metabolism of Crotalaria assamica and Eupatorium species.Chan MY, Zhao XL, Ogle CW

Datura metel, Solanaceae (as erroneous substitute) – See:

Vet Hum Toxicol 1995 Apr;37(2):156-7 Anticholinergic poisoning due to Chinese herbal medicines.Chan TY

J Trop Med Hyg. 1994 Dec;97(6):371-4. Herbal poisoning caused by adulterants or erroneous substitutes. But PP.

Datura stramonium, Solanaceae

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

Digitalis purpurea, Scrophulariaceae(Foxglove)

JAMA, Vol. 283, no. 7. Feb. 16, 2000. The herbal history of digitalis: lessons for alternative medicine.

Diploclisia spp., Menispermaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Dong Quai: See Angelica sinensis, Apiaceae

Dysosma pleiantha, Podophyllaceae – (podophyllotoxin toxicity)

Hum Exp Toxicol 1992 Nov;11(6):480-7 Podophyllotoxin intoxication: toxic effect of Bajiaolian in herbal therapeutics. Kao WF, Hung DZ, Tsai WJ, Lin KP, Deng JF

Ecballium elaterium, Curcurbitaceae

Vet Hum Toxicol 1999 Dec;41(6):376-8,Severe uvular angioedema caused by intranasal administration of Ecbalium elaterium. Eray O, Tuncok Y, Eray E, Gunerli A, Guven H

Echinacea – See: Echinacea spp., Asteraceae

Echinacea spp., Asteraceae

Health Care Reality Check FAQ – Echinacea. Maida Taylor, Helen Coleman

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Am J Med 1999 Feb;106(2):138-43 A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections. Grimm W, Muller HH

Arch Fam Med 1998 Nov-Dec;7(6):541-5 Echinacea root extracts for the prevention of upper respiratory tract infections: a double-blind, placebo-controlled randomized trial. Melchart D, Walther E, Linde K, Brandmaier R, Lersch C

Epazote – See: Chenopodium graveolens, Chenopodiaceae

Ephedra sinica, Ephedraceae -- (ephedrine toxicity)

J Pharm Sci 1998 Dec;87(12):1547-53 Ephedrine-type alkaloid content of nutritional supplements containing Ephedra sinica (Ma-huang) as determined by high performance liquid chromatography. Gurley BJ, Wang P, Gardner SF

Ther Drug Monit 1998 Aug;20(4):439-45 Ephedrine pharmacokinetics after the ingestion of nutritional supplements containing Ephedra sinica (ma huang). Gurley BJ, Gardner SF, White LM, Wang PL

Am J Gastroenterol 1996 Jul;91(7):1436-8 Acute hepatitis associated with the use of a Chinese herbal product, ma-huang. Nadir A, Agrawal S, King PD, Marshall JB

Erycibe obtusifolia, Convolvulaceae

J Ethnopharmacol 1998 Sep;62(2):101-5 Toxic effects of Erycibe obtusifolia, a Chinese medicinal herb, in mice. Hsu HY, Lin CC, Chen JY, Yang JJ, Zhang R

Eucalyptus globulus, Myrtaceae

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

J Paediatr Child Health 1993 Oct;29(5):368-71 Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. Webb NJ, Pitt WR.

Arch Dis Child 1980 May;55(5):405-6 Eucalyptus oil poisoning. Patel S, Wiggins J.

Eucalyptus oil – See: Eucalyptus globulus, Myrtaceae

Fang ji (Fang chi). See Aristolochia spp.

Fennel – See: Foeniculum vulgare, Apiaceae

Feverfew– See: Tanacetum parthenium, Asteraceae

Foeniculum vulgare, Apiaceae – (fennel)

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Fo-Ti – See: Polygonum multiflorum, Polygonaceae

Foxglove – See: Digitalis purpurea

Garlic – See: Allium sativa, Liliaceae

Germander – See: Teucrium chamaedrys

Ginger -- See: Zingiber officinale, Zingiberaceae

Ginkgo biloba, Ginkgoaceae

Health Care Reality Check FAQ – Ginkgo Biloba. Maida Taylor, Helen Coleman

BMJ 2001 Jan 13;322(7278):73 Effectiveness of Ginkgo biloba in treating tinnitus: double blind, placebo controlled trial. Drew S, Davies E

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Ginseng (Asian and American) – See: Panax ginseng and Panax quinquefolius, Araliaceae

Glycyrrhiza glabra, Fabaceae

Health Care Reality Check FAQ – Licorice. Maida Taylor, Helen Coleman

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Int J Eat Disord. 1999 Jul;26(1):111-4.Licorice-induced hypokalemic myopathy and hypokalemic renal tubular damage in anorexia nervosa. Ishikawa S, Kato M, Tokuda T, Momoi H, Sekijima Y, Higuchi M, Yanagisawa N.

J Intern Med. 1999 Mar;245(3):307-10.Life-threatening ventricular tachycardia due to liquorice-induced hypokalaemia. Eriksson JW, Carlberg B, Hillorn V.

Ital J Neurol Sci. 1997 Aug;18(4):217-20.Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. Barrella M, Lauria G, Quatrale R, Paolino E.

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

Ned Tijdschr Geneeskd. 1996 Dec 28;140(52):2632-5. Dutch. [Hypertension caused by licorice consumption]. Seelen MA, de Meijer PH, Braun J, Swinkels LM, Waanders H, Meinders AE, Meijer PH.

Ugeskr Laeger. 1996 Dec 16;158(51):7420-1.Danish. [Licorice. A basis for precautions one more time]! Folkersen L, Knudsen NA, Teglbjaerg PS.

Neth J Med. 1995 Nov;47(5):230-4. Liquorice-induced hypertension--a new understanding of an old disease: case report and brief review. Heikens J, Fliers E, Endert E, Ackermans M, van Montfrans G. Related Articles

An Med Interna. 1995 Jan;12(1):33-5. Spanish.[Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Berlango Jimenez A, Jimenez Murillo L, Montero Perez FJ, Munoz Avila JA, Torres Murillo J, Calderon de la Barca Gazquez JM.

Endocrinol Metab Clin North Am. 1994 Jun;23(2):359-77.Review. Licorice-induced hypertension and syndromes of apparent mineralocorticoid excess. Walker BR, Edwards CR.

J Hum Hypertens. 1994 May;8(5):371-5. Review. Apparent mineralocorticoid excess. Benediktsson R, Edwards CR.

J Steroid Biochem Mol Biol. 1993 Apr;45(1-3):1-5. Review. Congenital and acquired syndromes of apparent mineralocorticoid excess. Edwards CR, Walker BR, Benediktsson R, Seckl JR.

Rev Med Interne. 1993 Feb;14(2):121-2. French.[Perverse effects of an apparently harmless habit]. Michaux L, Lefebvre C, Coche E.

Nephrologie. 1993;14(4):177-81.French.[Hypokalemia without arterial hypertension by licorice poisoning]. Luchon L, Meyrier A, Paillard F. Related Articles

J Steroid Biochem Mol Biol. 1992 Oct;43(5):409-13. Review. Glucocorticoid-dependent hypertension. Mantero F, Boscaro M.

Ultrastruct Pathol. 1992 Sep-Oct;16(5):529-35. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. Caradonna P, Gentiloni N, Servidei S, Perrone GA, Greco AV, Russo MA.

J Electrocardiol. 1992 Apr;25(2):163-6.Giant negative U waves in a patient with uncontrolled hypertension and severe hypokalemia. Kanemoto N, Nakayama K, Ide M, Goto Y.

Z Kardiol. 1991 Jun;80(6):389-91. German.[Induction of arrhythmia by licorice abuse]. Bocker D, Breithardt G.

J Steroid Biochem Mol Biol. 1991;40(4-6):501-9.Review. The cortisol-cortisone shuttle and hypertension. Stewart PM, Edwards CR.

J Endocrinol Invest. 1990 Nov;13(10):847-8. Pseudohyperaldosteronism from liquorice-containing laxatives. Scali M, Pratesi C, Zennaro MC, Zampollo V, Armanini D.

Clin Ter. 1990 Jan 15;132(1):55-8. Italian. [Pseudo-hyperaldosteronism caused by licorice. Pathogenetic considerations and presentation of a clinical case].  Lorenzin F, Degen C, Milani A, Siciliano M, Rossi L.

Aust N Z J Med. 1989 Aug;19(4):365-7. Severe hypokalemic rhabdomyolysis due to ingestion of liquorice during Ramadan. Achar KN, Abduo TJ, Menon NK.

Endocrinology. 1989 Mar;124(3):1588-90. The antinatriuretic and kaliuretic effects of the glucocorticoids corticosterone and cortisol following pretreatment with carbenoxolone sodium (a liquorice derivative) in the adrenalectomized rat. Souness GW, Morris DJ.

Minerva Med. 1988 Mar;79(3):209-14. Italian. [Arterial hypertension with hypokalemia]. Montanari G, Zanaletti F, Quadrelli GC, Di Battista F, Ongis GA, Fraschini A, Zinzalini G, Abbiati C.

Minerva Med. 1988 Jan;79(1):55-60. Italian.[Hypopotassemia and rhabdomyolysis. Description of 3 cases of different etiologies]. Maresca MC, Calconi G, Amici GP, Teodori T, Da Porto A.

Postgrad Med J. 1987 Jul;63(741):589-90. Severe hypokalaemia from kaolin and morphine abuse. Kirkham B, Cowell R, Rees J.

Minerva Med. 1985 Apr 7;76(14-15):725-8. Italian. [L-carnitine chloride and potassium chloride in the treatment of a case of non-traumatic rhabdomyolysis without myoglobinuria caused by the ingestion of liquorice]. Ruggeri CS, Olivari G, Benvenuti ME, De Iacobis M, Peruzza M, Chinello M, Mazzolini GF, Rubini G.

Ital J Neurol Sci. 1984 Dec;5(4):463-6. Hypokalemic myopathy associated with liquorice ingestion. Cibelli G, De Mari M, Pozio G, Lamberti P.

Rev Neurol (Paris). 1984;140(3):207-11. French. [Hypokalemic paralysis after prolonged absorption of a non-alcoholic pastis in a diabetic]. de Rohan Chabot P, Gueguen B, Patte D, Gajdos P, Raphael JC, Goulon M.

Ann Med Interne (Paris). 1984;135(4):296-8. French. [Major hypokalemia with rhabdomyolysis secondary to the intake of a nonalcoholic aniseed aperitif]. Piette AM, Bauer D, Chapman A.

Ital J Neurol Sci. 1983 Dec;4(4):493-7. Acute hypokalemic myopathy due to chronic licorice ingestion: report of a case. Corsi FM, Galgani S, Gasparini C, Giacanelli M, Piazza G.

Riv Patol Nerv Ment. 1983 Jul-Aug;104(4):179-83. Italian. [Licorice-induced myopathy. Report of a new case]. Gibertoni M, Bonito V, Colombo A, Falasca A, Nichelli P.

Klin Wochenschr. 1983 Mar 15;61(6):303-5. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Heidemann HT, Kreuzfelder E.

Minerva Med. 1982 Sep 15;73(35):2279-86. Italian. [Hypokalemic myopathy in arterial hypertension]. Santeusanio F, Nunzi E, Natali P, Nicoletti I, Angeletti G, Filipponi P, Rambotti P. Related Articles

Postgrad Med J. 1981 Sep;57(671):577-9. Anorexia nervosa, liquorice and hypokalaemic myopathy. Nightingale S, Smith PE, Turnbull DM.

Minerva Med. 1981 Apr 2;72(13):825-30. Italian. [Pseudo-Conn's syndrome after habitual ingestion of liquorice. Report on various clinical cases]. Cuspidi C, Gelosa M, Moroni E, Sampieri L.

Postgrad Med J. 1981 Jan;57(663):48-9. Total body potassium depletion and severe myopathy due to chronic liquorice ingestion. Sundaram MB, Swaminathan R.

Postgrad Med J. 1980 Jul;56(657):526-9. Severe hypokalaemia with paralysis induced by small doses of liquorice. Cumming AM, Boddy K, Brown JJ, Fraser R, Lever AF, Padfield PL, Robertson JI.

Endocrinol Jpn. 1979 Oct;26(5):541-7.Prolonged pseudoaldosteronism induced by glycyrrhizin. Takeda R, Morimoto S, Uchida K, Nakai T, Miyamoto M, Hashiba T, Yoshimitsu K, Kim KS, Miwa U

Br Med J. 1977 Feb 19;1(6059):488-90.Effect of eating liquorice on the renin-angiotensin aldosterone axis in normal subjects. Epstein MT, Espiner EA, Donald RA, Hughes H.

Am J Hosp Pharm. 1975 Jan;32(1):73-4. Licorice-induced pseudoaldosteronism. Wash LK, Bernard JD.

Goldenseal – See: Hydrastis spp. (berberine toxicity)

Grape Seed Extract [GSE]

Ann Allergy Asthma Immunol  2002 Mar;88(3):272-8 Evaluation of the clinical efficacy and safety of grapeseed extract in the treatment of fall seasonal allergic rhinitis: a pilot study. Bernstein DI, Bernstein CK, Deng C, Murphy KJ, Bernstein IL, Bernstein JA, Shukla R.

Groundsel (Common groundsel) – See: Senecio spp.

Guang fang ji. See: Aristolochia, spp.

Hai Ge Fen (adulteration of) (This appears to be a reference to a clam, Cyclinae sinensis, which of course is a mollusk, not a plant – though traditional Chinese medicine tends to make little distinction between plant, animal, and mineral material. Bensky and Gamble discuss it by that Pinyin name on page 184.)

JAMA 1994 Mar 23-30;271(12):932-4 Lead poisoning due to hai ge fen. The porphyrin content of individual erythrocytes. Markowitz SB, Nunez CM, Klitzman S, Munshi AA, Kim WS, Eisinger J, Landrigan PJ

Hedeoma pulegioides, Lamiaceae & Mentha pulegium, Lamiaceae -- (pulegone and menthofuran toxicity)

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Ann Intern Med 1996 Apr 15;124(8):726-34 Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature. Anderson IB, Mullen WH, Meeker JE, Khojasteh-BakhtSC, Oishi S, Nelson SD, Blanc PD

J Am Vet Med Assoc 1992 Mar 15;200(6):817-8 Pennyroyal oil toxicosis in a dog. Sudekum M, Poppenga RH, Raju N, Braselton WE Jr

J Pharmacol Exp Ther 1990 May;253(2):567-72 Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione. Thomassen D, Slattery JT, Nelson SD

He-Shou-Wu – See: Polygonum multiflorum, Polygonaceae

Heliotropium spp., Boraginaceae

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Heracleum mantegazzianum, Apiaceae

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

HIV

J Acquir Immune Defic Syndr 1999 Sep 1;22(1):56-64 Randomized, placebo-controlled trial of Chinese herb therapy for HIV-1-infected individuals. Weber R, Christen L, Loy M, Schaller S, Christen S, Joyce CR, Ledermann U, Ledergerber B, Cone R, Luthy R, Cohen MR

Honey

Science 1977 Feb 4;195(4277):497-9 Pyrrolizidine alkaloids: their occurrence in honey from tansy ragwort. Deinzer ML, Thomson PA, Burgett DM, Isaacson DL

Hydrastis canadensis, Ranunculaceae – (goldenseal) (berberine toxicity)

Chem Res Toxicol 2001 Nov;14(11):1529-34 Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 1. Berberine. Inbaraj JJ, Kukielczak BM, Bilski P, Sandvik SL, Chignell CF.

Hypericum perforatum, Guttiferaceae – (hypericin and hyperflorin toxicity)

JAMA, Vol 287, No. 14, April 10, 2002 Effect of Hypericum perforatum (St. John’s Wort) in Major Depressive Disorder: A Randomized Controlled Trial. Hypericum Depression Trial Study Group

JAMA, Vol 285, No. 15, April 18, 2001 Effectiveness of St John's Wort in Major Depression: A Randomized Controlled Trial,  Richard C. Shelton, MD; Martin B. Keller, MD; Alan Gelenberg, MD; David L. Dunner, MD; Robert Hirschfeld, MD; Michael E. Thase, MD; James Russell, MD; R. Bruce Lydiard, MD, PhD; Paul Crits-Cristoph, PhD; Robert Gallop, PhD; Linda Todd; David Hellerstein, MD; Paul Goodnick, MD; Gabor Keitner, MD; Stephen M. Stahl, MD; Uriel Halbreich, MD

Psychopharmacology (Berl) 2001 Feb;153(4):402-14 St. John's wort (Hypericum perforatum): a review of the current pharmacological, toxicological, and clinical literature. Greeson JM, Sanford B, Monti DA

Transplantation 2001 Jan 27;71(2):239-41 Herbal supplements: a potential for drug interactions in transplant recipients. Barone GW, Gurley BJ, Ketel BL, Abul-Ezz SR

Cochrane Database Syst Rev 2000;(2):CD000448 St John's wort for depression. Linde K, Mulrow CD.

J Clin Psychiatry 2000 Nov;61(11):815-20 Adverse neuropsychiatric reactions to herbal and over-the-counter "antidepressants". Pies R

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Clin Pharmacol Ther 2000 May;67(5):451-7 St John's Wort: effect on CYP3A4 activity. Roby CA, Anderson GD, Kantor E, Dryer DA, Burstein AH

Pharmacotherapy 2000 May;20(5):568-74 Consumer use of St. John's wort: a survey on effectiveness, safety, and tolerability. Beckman SE, Sommi RW, Switzer J

J Psychopharmacol 2000 Mar;14(1):84-6 Mania in a patient receiving testosterone replacement postorchidectomy taking St John's wort and sertraline. Barbenel DM, Yusufi B, O'Shea D, Bench CJ

Lancet 2000 Feb 12;355(9203):548-9 Acute heart transplant rejection due to Saint John's wort. Ruschitzka F, Meier PJ, Turina M, Luscher TF, Noll G

Hautarzt 1997 Apr;48(4):249-52 [Reversible increase in photosensitivity to UV-B caused by St. John's wort extract]. [Article in German] Golsch S, Vocks E, Rakoski J, Brockow K, Ring J

Toxicol Lett 1982 Feb;10(2-3):183-8 Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes. Garrett BJ, Cheeke PR, Miranda CL, Goeger DE, Buhler DR

From “Indiana Plants Poisonous to Livestock and Pets” Website,Purdue University, School of Veterinary Medicine.

Hyssop – See: Hyssopus spp., Lamiaceae

Hyssopus spp., Lamiaceae – (pinocamphone and isopinocamphone toxicity)

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Rev Electroencephalogr Neurophysiol Clin 1979 Jan-Mar;9(1):12-8 [Experimental study of the toxic convulsant properties of commercial preparations of essences of sage and hyssop]. [Article in French] Millet Y, Tognetti P, Lavaire-Perlovisi M, Steinmetz MD, Arditti J, Jouglard J

Ilex paraguariensis, Aquifoliaceae– (unidentified toxins)

Br J Cancer 1998 Nov;78(9):1239-43 Meat intake, 'mate' drinking and renal cell cancer in Uruguay: a case-control study. De Stefani E, Fierro L, Mendilaharsu M, Ronco A, Larrinaga MT, Balbi JC, Alonso S, Deneo-Pellegrini H

Cancer Epidemiol Biomarkers Prev 1996 Jul;5(7):515-9 Mate drinking and risk of lung cancer in males: a case-control study from Uruguay. De Stefani E, Fierro L, Correa P, Fontham E, Ronco A, Larrinaga M, Balbi J, Mendilaharsu M

Braz J Med Biol Res 1994 Jul;27(7):1517-25 Mutagenic and genotoxic effects of mate (Ilex paraguariensis) in prokaryotic organisms. Leitao AC, Braga RS

Cancer Res 1990 Nov 15;50(22):7112-5 Patterns of mate drinking in a Brazilian city. Victora CG, Munoz N, Horta BL, Ramos EO

Jamu – See:

Ann Acad Med Singapore 1986 Jan;15(1):118-21 Drug eruptions from phenylbutazone in Jamu. Giam YC, Tham SN, Tan T, Lim A

Jin bu huan – See: Lycopodium serratum, Lycopodiaceae

Kan-mokutsu: (Presumably this is Caulis mutong, but the entry in Bensky at page 135 refers to 3 species in 3 different families --- typical confusion)

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Kava kava. See: Piper methysticum, Piperaceae

Klamath weed – See: Hypericum perforatum, Guttiferaceae

Kombucha tea – See: Acetobacter xylinum (bacteria) and various unidentified yeast species

Larrea tridentata, Zygophyllaceae

South Med J 1999 Nov;92(11):1095-7 Acute hepatitis after ingestion of herbs. Shad JA, Chinn CG, Brann OS

Arch Intern Med 1997 Apr 28;157(8):913-9 Chaparral-associated hepatotoxicity. Sheikh NM, Philen RM, Love LA

JAMA 1995 Feb 8;273(6):489-90 Chaparral ingestion. The broadening spectrum of liver injury caused by herbal medications. Gordon DW, Rosenthal G, Hart J, Sirota R, Baker AL

J Clin Gastroenterol 1994 Oct;19(3):242-7 Cholestatic hepatitis after ingestion of chaparral leaf: confirmation by endoscopic retrograde cholangiopancreatography and liver biopsy. Alderman S, Kailas S, Goldfarb S, Singaram C, Malone DG

MMWR Morb Mortal Wkly Rep 1992 Oct 30;41(43):812-4 Chaparral-induced toxic hepatitis--California and Texas, 1992. [no author cited]

J Clin Gastroenterol 1990 Apr;12(2):203-6 Herbal hepatitis: subacute hepatic necrosis secondary to chaparral leaf. Katz M, Saibil F

Lepiota helveola, Lepiotaceae (a mushroom).

Liver 1994 Jun;14(3):158-60 Liver transplantation for severe Lepiota helveola poisoning. Meunier B, Messner M, Bardaxoglou E, Spiliopoulos G, Terblanche J, Launois B

Licorice – See: Glycyrrhiza glabra, Fabaceae

Liquorice – See: Glycyrrhiza glabra, Fabaceae

Lycopodium serratum, Lycopodiaceae

J Hepatol 1998 Jan;28(1):165-7 Chronic hepatitis induced by Jin Bu Huan. Picciotto A, Campo N, Brizzolara R, Giusto R, Guido G, Sinelli N, Lapertosa G, Celle G

Arch Intern Med 1996 Apr 22;156(8):899-903 The clinical spectrum of Jin Bu Huan toxicity. Horowitz RS, Feldhaus K, Dart RC, Stermitz FR, Beck JJ.

Ann Intern Med 1994 Nov 15;121(10):729-35 Acute hepatitis associated with the Chinese herbal product jin bu huan. Woolf GM, Petrovic LM, Rojter SE, Wainwright S, Villamil FG, Katkov WN, Michieletti P, Wanless IR, Stermitz FR, Beck JJ, et al

MMWR Morb Mortal Wkly Rep 1993 Aug 27;42(33):633-6 Jin bu huan toxicity in children--Colorado, 1993.

Ma Huang – See: Ephedra sinica, Ephedraceae

Mandrake – See: Mandragora officinarum, Solanaceae

Mandragora officinarum, Solanaceae -- (hallucinogen) confused with Podophyllum peltatum – (podophyllotoxin toxicity)

Arch Intern Med 1997 Sep 22;157(17):2007-9 Mandrake toxicity. A case of mistaken identity. Frasca T, Brett AS, Yoo SD

Mate (yerba mate) – See: Ilex paraguariensis, Aquifoliaceae

Medicago sativa, Fabaceae (ssp. sativa)

FDA Special Nutritionals Adverse Event Monitoring System (SN/AEMS) Report on Alfalfa

Food Chem Toxicol 1984 Jul;22(7):583-7 Elimination of toxicity from diets containing alfalfa seeds. Malinow MR, McLaughlin P, Bardana EJ Jr, Craig S

Science 1982 Apr 23;216(4544):415-7 Systemic lupus erythematosus-like syndrome in monkeys fed alfalfa sprouts: role of a nonprotein amino acid. Malinow MR, Bardana EJ Jr, Pirofsky B, Craig S, McLaughlin P

Melaleuca alternifolia, Myrtaceae -- (cyclic terpene toxicity)

Contact Dermatitis 2001 Aug;45(2):65-67 Safety, efficacy and provenance of tea tree (Melaleuca alternifolia) oil. Carson CF, Riley TV.

Phytother Res 2000 Dec;14(8):623-9 Pharmacological and antimicrobial studies on different tea-tree oils (Melaleuca alternifolia, Leptospermum scoparium or Manuka and Kunzea ericoides or Kanuka), originating in Australia and New Zealand. Lis-Balchin M, Hart SL, Deans SG.

Am J Contact Dermat 2000 Dec;11(4):238-42 Allergic contact dermatitis to tea tree oil with erythema multiforme-like id reaction. Khanna M, Qasem K, Sasseville D

J Hosp Infect 2000 Nov;46(3):236-7 Tea tree oil as an alternative topical decolonization agent for methicillin-resistant Staphylococcus aureus. Caelli M, Porteous J, Carson CF, Heller R, Riley TV.

Audiol Neurootol 2000 Mar-Apr;5(2):64-8 A study of tea tree oil ototoxicity. Zhang SY, Robertson D.

Forsch Komplementarmed Klass Naturheilkd 2000 Feb;7(1):17-20 Tea tree oil: a systematic review of randomized clinical trials. Ernst E, Huntley A.

Am J Contact Dermat 1999 Jun;10(2):68-77 Degradation products of monoterpenes are the sensitizing agents in tea tree oil. Hausen BM, Reichling J, Harkenthal M.

Messybeast.com 1995, 1999 Tea Tree Oil – Toxic to Cats, Sarah Hartwell

Journal of Veterinary Diagnostic Investigation 10, 208 (1998) Australian tea tree (Melaleuca alternifolia) Oil Poisoning in three purebred cats. Bischoff K, Guale F

Toxicology 1996 Feb 22;107(2):99-109 Toxic effects of some conifer resin acids and tea tree oil on human epithelial and fibroblast cells. Soderberg TA, Johansson A, Gref R

Vet Hum Toxicol 1995 Dec;37(6):557-8 Melaleuca oil poisoning in a 17-month-old. Del Beccaro MA

Australas J Dermatol 1998 Nov;39(4):244-7 Tea tree oil allergy: what is the offending agent? Report of three cases of tea tree oil allergy and review of the literature. Rubel DM, Freeman S, Southwell IA.

Burns 1997 Jun;23(4):349-51 Does tea tree oil have a place in the topical treatment of burns? Faoagali J, George N, Leditschke JF

Vet Hum Toxicol 1994 Apr;36(2):139-42 Toxicity of melaleuca oil and related essential oils applied topically on dogs and cats .Villar D, Knight MJ, Hansen SR, Buck WB

Ned Tijdschr Geneeskd 1994 Apr 16;138(16):823-5 [Allergic contact eczema due to 'tea tree' oil] [Article in Dutch] van der Valk PG, de Groot AC, Bruynzeel DP, Coenraads PJ, Weijland JW.

J Am Acad Dermatol 1994 Mar;30(3):423-7 Melaleuca oil (tea tree oil) dermatitis. Knight TE, Hausen BM.

J Toxicol Clin Toxicol 1994;32(4):461-4 Melaleuca oil poisoning. Jacobs MR, Hornfeldt CS

Australas J Dermatol 1992;33(3):145-9 Tea tree oil in the treatment of tinea pedis. Tong MM, Altman PM, Barnetson RS.

Menispernum spp., Menispermaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Milk Thistle – See Silybum marianum, Asteraceae

Mokutsu: (Presumably this is Caulis mutong, but the entry in Bensky at page 135 refers to 3 species in 3 different families --- typical confusion)

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Monk’s Hood – See: Aconitum spp., Ranunculaceae

Monotes glaber, Dipterocarpaceae

Environ Mol Mutagen 1995;25(1):77-82 Frameshift mutations in Salmonella induced by the extracts of medicinal herbs Lannea edulis (Sond.) Engl. and Monotes glaber Sprague. Sohni YR, Davis CL, DesChamps AB, Kale PG

Mu tong

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Nettle – See: Urtica dioica, Urticaceae

Packera candidissima (Senecio candidissimus), Asteraceae– (pyrrolizidine alkaloid and terpene toxicity)

J Ethnopharmacol 1994 Jun;43(1):19-30 Hepatotoxic pyrrolizidine alkaloids in the Mexican medicinal plant Packera candidissima (Asteraceae: Senecioneae). Bah M, Bye R, Pereda-Miranda R

Panax ginseng and Panax quinquefolius, Araliaceae (Asian and American Ginseng)

Drug Saf 2002;25(5):323-44 Panax ginseng: A Systematic Review of Adverse Effects and Drug Interactions. Coon JT, Ernst E.

http://www.hc-sc.gc.ca/english/protection/warnings/2002/2002_09e.htm

Health Canada warns public not to use Hua Fo.Health Canada, February 15, 2002

Product Review: Asian and American Ginseng, ConsumerLab.com, 2000.

Health Care Reality Check FAQ – Ginseng.Maida Taylor, Helen Coleman

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Sports Med 2000 Feb;29(2):113-33 Evaluation of the ergogenic properties of ginseng: an update. Bahrke MS, Morgan WR.

Passiflora incarnata, Passifloraceae – (unidentified toxin)

Tidsskr Nor Laegeforen 1997 Mar 20;117(8):1140-1 [Nature medicine as intoxicant]. [Article in Norwegian] Solbakken AM, Rorbakken G, Gundersen T

Pausinystalia yohimba, Rubiaceae (yohimbe) (yohimbine toxicity)

Urology 1993 Apr;41(4):343-5 Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Sandler B, Aronson P.

Pennyroyal Oil – See: Hedeoma pulegioides, Lamiaceae & Mentha pulegium, Lamiaceae

Pimpinella anisum, Apiaceae

FDA Special Nutritionals Adverse Event Monitoring System (SN/AEMS) Report on Anise

Piper methysticum, Piperaceae (kava kava)

Dtsch Med Wochenschr 1998 Nov 20;123(47):1410-4 [Necrotizing hepatitis after taking herbal remedies]. [Article in German] Strahl S, Ehret V, Dahm HH, Maier KP

Hautarzt 1996 Jun;47(6):459-61 [Hematogenous contact eczema cause by phytogenic drugs exemplified by kava root extract] [Article in German] Suss R, Lehmann P.

Clin Exp Pharmacol Physiol 1990 Jul;17(7):509-14 Positive interaction of ethanol and kava resin in mice. Jamieson DD, Duffield PH.

Piyan Ping 999 ointment (adulteration of) – See:

Ned Tijdschr Geneeskd. 1997 Aug 16;141(33):1626. Dutch.[Dexamethasone in a non-registered ointment from the Far East]. de Smet PA, Wagenaar HW, Smeets OS.

Podophyllum emodi, Berberidaceae (as an adulterant):

J Trop Med Hyg. 1994 Dec;97(6):371-4. Herbal poisoning caused by adulterants or erroneous substitutes. But PP.

J Toxicol Clin Toxicol 1982 Mar;19(1):35-44 Podophyllum toxicity: a report of a fatal case and a review of the literature. Cassidy DE, Drewry J, Fanning JP

Polygonum multiflorum, Polygonaceae

Vet Hum Toxicol. 1996 Aug;38(4):280-2.Hepatitis related to the Chinese medicine Shou-wu-pian manufactured from Polygonum multiflorum. But PP, Tomlinson B, Lee KL.

Pteridium aquilinum, Dennstaedtiaceae. (Bracken fern)

Toxicol Lett 1982 Feb;10(2-3):183-8 Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes. Garrett BJ, Cheeke PR, Miranda CL, Goeger DE, Buhler DR

Ragwort – See: Senecio spp., Asteraceae

Ranunculus bulbosus, Ranunculaceae

Vet Hum Toxicol 1992 Jun;34(3):238-9 Suspected buttercup (Ranunculus bulbosus) toxicosis with secondary photosensitization in a Charolais heifer. Kelch WJ, Kerr LA, Adair HS, Boyd GD

Red Clover – See: Trifolium pratense, Fabaceae

Relaxir – See: Passiflora incarnata, Passifloraceae

Rosemary – See: Rosmarinus officinalis, Lamiaceae

Rosmarinus officinalis, Lamiaceae

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Rutae Herba – See: Ruta spp., Rutaceae

Ruta spp.,Rutaceae -- (furoquinoline alkaloid toxicity)

Mutagenesis 1989 Nov;4(6):467-70 The SCE-inducing potency of the furoquinoline alkaloid, gamma-fagarine, and a gamma-fagarine-containing tincture from Rutae Herba, in cultured human lymphocytes. Schimmer O, Leimeister U

Sage – See: Salvia officinalis, Lamiaceae

Salvia fruticosa, Lamiaceae

J Ethnopharmacol 1998 May;61(1):67-74 Published erratum appears in J Ethnopharmacol 1998 Dec;63(3):265 Reproductive toxicity potentials of Salvia fruticosa (Labiatae) in rats. Al-Hamood MH, Elbetieha A, Alkofahi A, Bataineh H

Salvia officinalis, Lamiaceae – (terpene and camphor toxicity)

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Planta Med 1991 Jun;57(3):237-41 Studies on the genotoxic properties of essential oils with Bacillus subtilis rec-assay and Salmonella/microsome reversion assay. Zani F, Massimo G, Benvenuti S, Bianchi A, Albasini A, Melegari M, Vampa G, Bellotti A, Mazza P

Rev Electroencephalogr Neurophysiol Clin 1979 Jan-Mar;9(1):12-8 [Experimental study of the toxic convulsant properties of commercial preparations of essences of sage and hyssop]. [Article in French] Millet Y, Tognetti P, Lavaire-Perlovisi M, Steinmetz MD, Arditti J, Jouglard J

Saw Palmetto – See: Serenoa repens or (Serenoa serrulata), Arecaceae

Scullcap – See: Scutellaria spp., Lamiaceae

Scutellaria spp., Lamiaceae

Reprod Toxicol 1993;7(1):73-9 Teratogenicity study of Scutellariae Radix in rats. Kim SH, Kim YH, Han SS, Roh JK

Senecio spp., Asteraceae. (pyrrolizidine alkaloid toxicity: senecionine, seneciphylline, jacoline, jaconine, jacobine, and jacozine -- potentially carcinogenic, mutagenic, and teratogenic toxins.)

From “Indiana Plants Poisonous to Livestock and Pets” Website,Purdue University, School of Veterinary Medicine.

Vet Hum Toxicol 1999 Jun;41(3):129-33 Interactions in sheep between tall fescue ergot alkaloids and hepatotoxic carbon tetrachloride and Senecio pyrrolizidine alkaloids. Debessai WT, Huan J, Cheeke PR

J Nat Toxins 1998 Feb;7(1):87-93 Pyrrolizidine alkaloids from Senecio nevadensis. Bourauel T, Plassmeier C, Roeder E

Schweiz Med Wochenschr 1996 Jun 22;126(25):1085-98 [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. [Article in German] Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B, Meier-Abt PJ

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Vet Hum Toxicol 1984 Apr;26(2):108-11 Large scale extraction of pyrrolizidine alkaloids from tansy ragwort (Senecio jacobaea). Craig AM, Sheggeby G, Wicks Ce

J Anim Sci 1984 May;58(5):1245-54 Mutagenic responses of tansy ragwort (Senecio jacobaea) plant, pyrrolizidine alkaloids and metabolites in goat milk with the Salmonella/mammalian-microsome mutagenicity test. White RD, Krumperman PH, Cheeke PR, Deinzer ML, Buhler DR

J Anim Sci 1984 Apr;58(4):1029-39 Teratogens in plants. Keeler RF

Equine Vet J 1983 Jul;15(3):248-50 Outbreak of ragwort (Senecio jacobaea) poisoning in horses. Giles CJ

J Anim Sci 1982 Dec;55(6):1411-6 Effect of dietary Senecio jacobaea and injected Senecio alkaloids and monocrotaline on guinea pigs. Swick RA, Cheeke PR, Goeger DE, Buhler DR

Toxicol Lett 1982 Feb;10(2-3):183-8 Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes. Garrett BJ, Cheeke PR, Miranda CL, Goeger DE, Buhler DR

Toxicol Lett 1980 May;5(6):369-74 The effect of pyrrolizidine alkaloids (Senecio vulgaris) on the liver mixed-funcion oxidase system. Eastman DF, Segall HJ

Ann Pharm Fr 1979;37(1-2):13-20 [Senecio vulgaris L. (Compositae) toxicity for liver]. [Article in French] Delaveau P, Ferry S, Barbagelatta M, Casper C

Am J Vet Res 1978 Sep;39(9):1542-4 Tolerance of cattle to tansy ragwort (Senecio jacobaea). Johnson AE

Gastroenterology 1977 Aug;73(2):349-52 Hepatic veno-occlusive disease due to pyrrolizidine (Senecio) poisoning in Arizona. Stillman AS, Huxtable R, Consroe P, Kohnen P, Smith S

Science 1977 Feb 4;195(4277):497-9 Pyrrolizidine alkaloids: their occurrence in honey from tansy ragwort. Deinzer ML, Thomson PA, Burgett DM, Isaacson DL

S Afr Med J 1976 Jul 3;50(28):1096-9 Herb use and necrodegenerative hepatitis. Mokhobo KP

Am J Vet Res 1976 Jan;37(1):107-10 Changes in calves and rats consuming milk from cows fed chronic lethal doses of Senecio jacobaea (tansy ragwort). Johnson AE

S Afr Med J 1972 Jul 22;46(30):1039-43 Senecio species: toxic plants used as food and medicine in the Transkei. Rose EF

Trop Geogr Med 1972 Jun;24(2):194-8 Prevention or cure? Use of toxic herbs and geographic pathology. [No abstract available.] Schoental R

Pharmacol Rev 1970 Dec;22(4):429-83 The toxic actions of pyrrolizidine (senecio) alkaloids. [Review – no abstract available] McLean EK

Trop Geogr Med 1970 Jun;22(2):201-10 Hepatotoxicity of Senecio abyssinicus. Experimental and ultrastructural studies. [No abstract available.] Williams AO, Schoental R

Aust J Exp Biol Med Sci 1970 Feb;48(1):93-103 A method for the assessment of the chronic hepatoxicity of pyrrolizidine alkaloids. [No abstract available] Jago MV

Am J Pathol 1969 Sep;56(3):405-21 The development of the hepatic megalocytosis of chronic pyrrolizidine alkaloid poisoning. [No abstract available] Jago MV

Rev Fr Etud Clin Biol 1969 Feb;14(2):192-212 [Toxic hepatitis]. [No abstract available.] [Article in French] Sicot C, Bismuth C, Frejaville JP, Berthelot P, Rueff B, Benhamou JP

J Comp Pathol 1968 Apr;78(2):207-18 Serum changes following the feeding of ragwort (Senecio jacobaea) to calves. [No abstract available.] Ford EJ, Ritchie HE, Thorpe E

J Comp Pathol 1968 Apr;78(2):195-205 Development of hepatic lesions in calves fed with ragwort (Senecio jacobea) . [No abstract available.] Thorpe E, Ford EJ

Am J Pathol 1966 Jul;49(1):129-51 Delayed hepatitis and cirrhosis in weanling rats following a single small dose of the senecio alkaloid, lasiocarpine. [No abstract available] Nolan JP, Scheig RL, Klatskin G

Serona Repens (or Serona Serrulata), Arecaceae

Product Review: Saw Palmetto, Consumerlab.com, 2000

Silybum marianum, Asteraceae

Health Care Reality Check FAQ – Milk Thistle. Maida Taylor, Helen Coleman

MJA 1999; 170: 218-219 An adverse reaction to the herbal medication milk thistle (Silybum marianum)

Nurses' Drug Alert 23(7):51, 1999.Adverse Reaction : Milk Thistle-Associated Toxicity

Sinomenium spp., Menispermaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Shou-Wu-Pian – See: Polygonum multiflorum, Polygonaceae

St. John’s Wort – See: Hypericum perforatum, Guttiferae

Stephania spp., Menispermaceae

FDA bulletin, May 31, 2000,Letter to Health Care Professionals - FDA Concerned About Botanical Products, Including Dietary Supplements, Containing Aristolochic Acid

Symphytum officinale, Boraginaceae – (pyrrolizidine alkaloid toxicity)

Public Health Nutr 2000 Dec;3(4A):501-8 The efficacy and safety of comfrey. Stickel F, Seitz HK.

Nat Toxins 1996;4(4):163-7 Analysis, separation, and bioassay of pyrrolizidine alkaloids from comfrey (Symphytum officinale). Couet CE, Crews C, Hanley AB

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Int J Exp Pathol 1993 Apr;74(2):211-7 Hepatocyte membrane injury and bleb formation following low dose comfrey toxicity in rats. Yeong ML, Wakefield SJ, Ford HC

Toxicol Lett 1982 Feb;10(2-3):183-8 Consumption of poisonous plants (Senecio jacobaea, Symphytum officinale, Pteridium aquilinum, Hypericum perforatum) by rats: chronic toxicity, mineral metabolism, and hepatic drug-metabolizing enzymes. Garrett BJ, Cheeke PR, Miranda CL, Goeger DE, Buhler DR

Experientia 1980 Apr 15;36(4):377-9 Structure and toxicity of the alkaloids of Russian comfrey (symphytum x uplandicum Nyman), a medicinal herb and item of human diet. Culvenor CC, Clarke M, Edgar JA, Frahn JL, Jago MV, Peterson JE, Smith LW

Tanacetum parthenium, Asteraceae – (feverfew) (parthenolide /sesquiterpene lactone contact allergic reaction)

Cochrane Database Syst Rev 2000;(3):CD00228 Feverfew for preventing migraine. Pittler MH, Vogler BK, Ernst E.

Acta Derm Venereol 1983;63(4):308-14 Contact allergy to parthenolide in Tanacetum parthenium (L.) Schulz-Bip. (feverfew, Asteraceae) and cross-reactions to related sesquiterpene lactone containing Compositae species. Hausen BM, Osmundsen PE

Tanacetum vulgare, Asteraceae (tansy) (thujone toxicity)

J Neurol 1999 Aug;246(8):667-70 Plant-induced seizures: reappearance of an old problem. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T.

Tansy – See: Tanacetum vulgare, Asteraceae

Tansy ragwort – See: Senecio jacobaea and other species of Senecio

Tea Tree Oil – See: Melaleuca alternifolia, Myrtaceae

Teucrium chamaedrys, Lamiaceae(germander, wild germander)

CMAJ 1996 Jun 1;154(11):1689-92 Hepatitis after the use of germander, a herbal remedy. Laliberte L, Villeneuve JP

Presse Med 1994 Apr 16;23(15):691-3 [Liver involvement in the course of phytotherapy]. [Article in French] Larrey D

Gastroenterol Clin Biol 1993;17(12):959-62 [Chronic active hepatitis and cirrhosis induced by wild germander. 3 cases]. [Article in French] Ben Yahia M, Mavier P, Metreau JM, Zafrani ES, Fabre M, Gatineau-Saillant G, Dhumeaux D, Mallat A

Gastroenterol Clin Biol 1992;16(10):798-800 [Liver damage induced by the ingestion of a product of phytotherapy containing wild germander. Four cases]. [Article in French] Mattei A, Bizollon T, Charles JD, Debat P, Fontanges T, Chevallier M, Trepo C

Ann Intern Med 1992 Jul 15;117(2):129-32 Hepatitis after germander (Teucrium chamaedrys) administration: another instance of herbal medicine hepatotoxicity. Larrey D, Vial T, Pauwels A, Castot A, Biour M, David M, Michel H

Gastroenterol Clin Biol 1992;16(1):92-5 [Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases]. [Article in French] Pauwels A, Thierman-Duffaud D, Azanowsky JM, Loiseau D, Biour M, Levy VG

Trifolium pratense, Fabaceae

Appl Environ Microbiol 1981 Dec;42(6):1067-73 Salivary syndrome in horses: identification of slaframine in red clover hay. Hagler WM, Behlow RF

Aust J Biol Sci 1985;38(1):109-13 Seasonal changes in LH secretion in normal ewes and ewes which grazed oestrogenic clover. Chamley WA, Clarke IJ, Moran AR

Tripterygium wilfordii, Celastraceae – (diterpene lactone epoxide toxicity)

Mol Pharmacol 2000 Mar;57(3):512-8 Hematotoxicity of the chinese herbal medicine Tripterygium wilfordii hook f in CD34-positive human bone marrow cells. Pyatt DW, Yang Y, Mehos B, Le A, Stillman W, Irons RD

Int J Cardiol 1995 Apr;49(2):173-7 Hypovolemic shock and mortality after ingestion of Tripterygium wilfordii hook F.: a case report. Chou WC, Wu CC, Yang PC, Lee YT

Contraception 1995 Jan;51(1):65-71 Adverse effect of Tripterygium wilfordii extract on mouse embryonic development. Chan WY, Ng TB

Arch Biochem Biophys 1993 May 15;303(1):165-71 The hydroxylation of plant diterpene analogues by the fungus Syncephalastrum racemosum. Milanova R, Moore M

Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1991 Dec;13(6):391-7 [Screening of active anti-inflammatory, immunosuppressive and antifertility components of Tripterygium wilfordii. III. A comparison of the antiinflammatory and immunosuppressive activities of 7 diterpene lactone epoxide compounds in vivo]. [Article in Chinese] Zheng J

Tussilago farfara, Asteraceae – (senkirkine toxicity)

Gann 1976 Feb;67(1):125-9 Carcinogenic activity of coltsfoot, Tussilago farfara l. Hirono I, Mori H, Culvenor CC

Urtica dioica, Urticaceae

Teratog Carcinog Mutagen 1996;16(2):125-38 An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. Basaran AA, Yu TW, Plewa MJ, Anderson D

Valerian - See: Valeriana officianalis, >Valerianaceae

Valeriana officianalis, Valerianaceae

Product Review – Valerian.ConsumerLab.com

Z Arztl Fortbild Qualitatssich 2001 Jan;95(1):33-4 [Phytochemicals as means to induce sleep]. [Article in German]. Volz HP.

Ceska Slov Farm 2000 Jul;49(4):162-7 [Interactions between herbal medicines and drugs]. [Article in Czech] Tumova L.

Arzneimittelforschung 1993 Jun;43(6):638-41 Characterisation of the central nervous depressant activity of a commercially available valerian root extract. Leuschner J, Muller J, Rudmann M.

Veratrum californicum, Asteraceae

Wild germander – See: Teucrium chamaedrys

Wikstroemia chamaedaphne, Thymelaeaceae – (unidentified carcinogen)

Shih Yen Sheng Wu Hsueh Pao 1991 Dec;24(4):307-15 [Effects of tumor promoting herb Wikstroemia chamaedaphne extract on V79 cells and WB liver cells: I. Correlation between cellular growth and gap junctional intercellular communication]. [Article in Chinese] Lin ZX, Lu GZ, Jiang SW, Zhou LX, Han YL

Yerba mate – See: Ilex paraguariensis, Aquifoliaceae

Yin-chen – See: Artemisia scoparia, Asteraceae and Coptis spp., Ranunculaceae. (This is another good example of a confusing Chinese name for two very unrelated species in different families.)

Yohimbe – See: Pausinystalia yohimba, Rubiaceae

Zigadenus spp., Melanthiaceae (Liliaceae s.l.)

Ann Emerg Med 1995 Feb;25(2):259-62 Zigadenus poisoning. Heilpern KL

Zingiber officinale, Zingiberaceae

Br J Anaesth 2000 Mar;84(3):367-71 Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Ernst E, Pittler MH

Anaesth Intensive Care. 1995 Aug;23(4):449-52. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Arfeen Z, Owen H, Plummer JL, Ilsley AH, Sorby-Adams RA, Doecke CJ.

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