Additional Sources


The following are citations of medical reports and articles relating to the adverse effects (including Serotonin Syndrome) and the withdrawal syndrome associated with Venlafaxine. Some are linked to directly from this site (see Research Links), others are referred to in the Social Audit table:

  1. Randomski JW - An explanatory approach to the serotonin syndrome: an update of clinical phenomenology and revised diagnostic criteria - Med Hypothesis 2000 Sep;55(3):218-224
  2. Bjorvatn B - Venlafaxine and its interaction with WAY 100635 - Eur J Pharmacol 2000 Sep 15;404(1-2):121-132
  3. Mason PJ - Serotonin Syndrome. Presentation of 2 cases and review of the literature - Medicine (Baltimore) 2000 Jul;79(4):201-9
  4. Prost N - St. Johns wort - venlafaxine interaction - Presse Med 2000 Jul 1;29(23):1285-6
  5. Cassidy EM - Neuroleptic malignant syndrome after venlafaxine - Lancet 2000 Jun 17;355(9221):2164-5
  6. Black K - SSRI discontinuation syndrome: proposed diagnostic criteria - J Psychiatry Neurosci 2000 May;25(3):255-61
  7. Pinzani V - Report on six cases of withdrawal symptoms on venlafaxine discontinuation - Rev Med Interne 2000 Mar;21(3):282-4
  8. Cardona X - Venlafaxine associated hepatitis - Annals of Internal Medicine 2000 Mar;7132(5):417
  9. Fleish MC - Eosinophilic pneumonia and respiratory failure associated with venlafaxine treatment - European Respiratory Journal 2000 Jan;15(1):205-8
  10. Nimmagadda SR - Neuroleptic malignant syndrome after venlafaxine - The Lancett 2000 Jan 22;355(9200):289-90
  11. Michael A - Venlafaxine - induced painful ejaculation - Br J Psychiatry 2000 177:282-283
  12. Sierra Santos L - Venlafaxine and it's discontinuation syndrome - Aten Primaria 1999 Dec;24(10)-617-8
  13. Mackay FJ - Antidepressants and the serotonin syndrome in general practice - Br J Gen Pract 1999 Nov;49(448):871-4
  14. Schwartz TL - Diaphoresis and pruritus with extended release venlafaxine - Ann Pharmacother 1999 Sep;33(9):1009
  15. Reznik I - An acute ischaemic event associated with the use of venlafaxine: a case report and proposed pathophysiological mechanisms - Journal of Psychopharmacology (Oxf) 1999;13(2):193-5
  16. Horsmans Y - Venlafaxine associated hepatitis - Annals of Internal Medicine 1999 Jun 1;130(11):944
  17. Blythe D - Cardiovascular and neurological toxicity of venlafaxine - Hum Exp Toxicol 1999 May;18(5):309-13
  18. Kim KY - Acute liver damage possibly related to sertraline and venlafaxine ingestion - Ann Pharmacother 1999 Mar;33(3):381-2
  19. Dewan MJ - Evaluating the tolerability of the newer antidepressants - J Nerv Ment Dis 1999 Feb;187(2):96-101
  20. Jaffe PD - A study involving venlafaxine overdoses: comparison of fatal and therapeutic concentrations in postmortem specimens - J Forensic Sci 1999 Jan;44(1):193-6
  21. Banham ND - Fatal venlafaxine overdose - Medical Journal of Australia 1998 Oct 19;169(8):445,448
  22. Dailal A - Withdrawal and rebound symptoms associated with abrupt discontinuation of venlafaxine - Journal of Clinical Psychopharmacology 1998 Aug;18(4):343-4
  23. Settle EC Jr. - Antidepressant Drugs: distrurbing and potentially dangerous adverse effects - Journal of Clinical Psychiatry 1998; 59 Suppl 16:25-30
  24. Raby WN. - Treatment of venlafaxine discontinuation symptoms with ondansetron - Journal of Clinical Psychiatry - 1998 Nov;59(11):621-2
  25. Daniels RJ. - Serotonin syndrome due to venlafaxine overdose - Journal of Accident and Emergency Medicine 1998 Sep; 15(5):333-4
  26. Boyd IW. - Venlafaxine withdrawal reactions - Medical Journal of Australia 1998 Jul 20; 169(2):91-2
  27. Zedkova L - Severe anticholinergic side effects with venlafaxine-fluoxetine combination - Canadian Journal of Psychiatry 1998 Jun;43(5):523
  28. Coorey AN - Venlafaxine overdose - Medical Journal of Australia 1998 May18;168(10):523
  29. Benazzi F - Venlafaxine drug-drug interactions in clinical practice - J Psychiatry Neuroscience 1998 May;23(3):181-2
  30. Macbeth R. Rajagopalan M. - Venlafaxine withdrawal syndrome - Australia and New Zealand Journal of Medicine 1998 Apr;28(2):218
  31. Aragona M - Increased ocular pressure in two patients with narrow angle glaucoma treated with venlafaxine - Clin Neuropharmacol 1998 Mar-Apr;21(2):130-1
  32. Bhatara VS - Serotonin syndrome induced by venlafaxine and fluoxetine: a case study in polypharmacy and potential pharmacodynamic and pharmacokinetic mechanisms - Ann Pharmacother 1998 Apr;32(4):432-6
  33. Weiner LA - Serotonin syndrome secondary to phenelzine-venlafaxine interaction - Pharmacotherapy 1998 Mar-Apr;18(2):399-403
  34. Benazzi F - Anticholinergic toxic syndrome with venlafaxine-desipramine combination - Pharmacopsychiatry 1998 Jan;31(1):36-7
  35. Leaf EV - Comment: venlafaxine overdose and seizure - Ann Pharmacother 1998 Jan;32(1):135-6
  36. Masood GR - Hyponatremia with venlafaxine - Ann Pharmacother 1998 Jan;32(1):49-51
  37. Mekler G. Woggon B. - A case of serotonin syndrome caused by venlafaxine and lithium - Pharmacopsychiatry 1997 Nov;30(6) 272-3
  38. Benazzi F - Severe anticholigernic side effects with venlafaxine-fluoxetine combination - Can J Psychiatry 1997 Nov;42(9):980-1
  39. Zhalkovsky B - Seizure activity and enzyme elevations after venlafaxine overdose - J Clin Psychopharmacol 1997 Dec;17(6):490-1
  40. Amchin J - Clinical considerations in managing nausea associated with venlafaxine - J Clin Psychopharmacol 1997 Dec;17(6):489-90
  41. Wolfe RM - Antidepressant withdrawal reactions - American Family Physician 1997 Aug;56(2):455-62
  42. Kolecki P. - Isolated venlafaxine induced serotonin syndrome - Journal of Emergency Medicine 1997 Jul-Aug;15(4):491-3
  43. Adesenya A - Overdose of venlafaxine - a newer antidepressant - Med J Australia 1997 Jul 7;167(1):54
  44. Meynaar IA - Syndrome of inappropriate ADH secretion attributed to the serotonin re-uptake inhibitors, venlafaxine and paroxetine - Neth J Med 1997 Jun;50(6):243-5
  45. Durback LF - Comment: seizure resulting from venlafaxine overdose - Ann Pharmacother 1997 Jun;31(6):790-1
  46. Gupta AK - Venlafaxine induced hyponatremia - J Clin Psychopharmacol 1997 Jun;17(3):223-5
  47. Lane R - SSRI induced serotonin syndrome: review - J Clin Psychopharmacol 1997 Jun;17(3):208-21
  48. Dagg PK - Toxicity in venlafaxine overdose - J Psychiatry Neurosci 1997 May;22(3):201-2
  49. Ravsten DV - Spontaneous male orgasm in association with venlafaxine - Am Fam Physician 1997 Apr;55(5): 1561, 1564, 1574
  50. Rosenbaum JF. Zajeka J. - Clinical management of antidepressant discontinuation - Journal of Clinical Psychiatry 1997; 58 Suppl 7::37-40
  51. Haddad P. - Newer antidepressants and the discontinuation syndrome - Journal of Clinical Psychiatry 1997; 58 Suppl 7:17-21
  52. Cavanuagh GL - Venlafaxine and urinary incontinence: possible association - Ann Pharmacother 1997 Mar;31(3):372
  53. White CM - Seizure resulting from a venlafaxine overdose - Ann Pharmacother 1997 Feb;31(2):178-80
  54. Parsons AT - Two fatal cases of venlafaxine poisoning - J Anal Toxicol. 1996 Jul-Aug;20(4):266-8
  55. Ereshefsky L - Drug-drug interactions involving antidepressants: focus on venlafaxine - J Clin Psychpharmacol 1996 Jun;16(3 suppl 2):37S-50S;discussion 50S-53S. Review.
  56. Rudolph RL - The safety and tolerability of venlafaxine hydrochloride: analysis of the clinical trials database - J Clin Psychpharmacol 1996 Jun;16(3 suppl 2):54S-59S;discussion 59S-61S. Review.
  57. Russell JL - Relatively low doses of cisapride in the treatment of nausea in patients treated with venlafaxine for treatment-refractory depression - J Clin Psychopharmacol 1996 Feb;16(1):35-7
  58. Heisler MA - Serotonin syndrome induced by administration of venlafaxine and phenelzine - Ann Pharmacother 1996 Jan;30(1):84
  59. Ahmad S - Venlafaxine and severe tinnitus - Am Fam Physician 1995 Jun;51(8):1830
  60. Fantaskey A - A case report of venlafaxine toxicity - J Toxicol Clin Toxicol 1995;33(4):359-61



Return to Table of Contents

Last Updated 2 October 2000 by Steve Whiting