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Neuroscience News

NIH Neuroscience Blueprint to Shape Intra-Agency Research Cooperation
Sunday, October 24, 2004
National Institutes of Health Director Elias A. Zerhouni, M.D., today announced a new intra-agency partnership to accelerate neuroscience research. Dubbed the NIH Blueprint for Neuroscience Research, the agreement reinforces ongoing NIH efforts to increase collaborative research and information-sharing among 14 NIH Institutes and Centers that conduct or support research on the brain and nervous system.  
 

A montage of four images of the development of a single neuron over a two-week period. The neuron was transfected with green flourescent protein and a microscope imaged the neuron 3 hours, 64 hours, 113 hours, and 137 hours later. Study Using Robotic Microscope Shows How Mutant Huntington's Disease Protein Affects Neurons
Wednesday, October 13, 2004
Using a specially designed robotic microscope to study cultured cells, researchers have found evidence that abnormal protein clumps called inclusion bodies in neurons from people with Huntington's disease (HD) prevent cell death. The finding helps to resolve a longstanding debate about the role of these inclusion bodies in HD and other disorders and may help investigators find effective treatments for these diseases.   Fact Sheet
 

Brain Imaging May Identify High Risk Stroke Patients
Thursday, October 07, 2004
By using sophisticated magnetic resonance imaging (MRI) technology, researchers have been able to study early changes in the blood-brain barrier (BBB), a semi-permeable membrane that surrounds and protects the brain, to predict a stroke patient's outcome. This study showed that the patients who had disruption in the BBB were more likely to experience bleeding in the brain and have a poor clinical outcome. The researchers say this technique could help identify patients who are most likely to do the best with thrombolytic therapy, and to help clinicians offer additional therapies to those who might suffer complications.   Fact Sheet
 

Reorganization of the Brain Allows Blind Individuals to Process Speech More Effectively
Monday, October 04, 2004
The portion of the brain devoted to vision may play a prominent role in processing the spoken word in blind people. Research conducted by the NIH's National Institute of Neurological Disorders and Stroke (NINDS) shows that the "sight" region of the brain is essentially reorganized in blind individuals to help them process spoken words more effectively. The findings yield important information about the brain's ability to compensate for lost function.  
 

Gene Silencing Prevents Brain Disease in Mice
Thursday, September 23, 2004
Scientists studying a mouse model of spinocerebellar ataxia 1 (SCA1) have found an effective way to "silence" the mutant gene allele or variant that causes the disorder while leaving the normal gene allele unaffected.   Fact Sheet
 

Gene for Rapid-Onset Dystonia Parkinsonism Found
Thursday, September 23, 2004
Investigators funded in part by the National Institute of Neurological Disorders and Stroke (NINDS) have identified the gene responsible for a rare form of dystonia known as rapid-onset dystonia parkinsonism (RDP).   Fact Sheet
 
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