HEI's website is regularly updated with the latest news and
results. Thank you for visiting!
Fall 2004 HEI Update now online!
about an upcoming review of the current science on the possible health
effects of mobile-source related air toxics; a soon-to-be published study of
the effects of ultrafine carbon particles on human airways; three new studies
of air pollution and health in India; several reports that will be published
soon; this year's winners of our new investigator awards, and much more.
To download the newsletter, click
here (PDF, 870 KB).
HEI issues Fall 2004 Research Agenda –
HEI has issued Requests for Applications on Measuring the Health Impacts of Actions
to Improve Air Quality (Accountability), the New Investigator
Award, and Preliminary Applications on the Health Effects of Air Pollution on
HEI's funding page. The RFA booklet is now available for downloading.
PM Workshop presentations available – October 2004
part of its initiative to implement a systematic approach to a key PM research
need looking forward, HEI held a workshop "Research to Investigate the
Characteristics and Sources of PM Associated with Toxicity" in August
2004 in Baltimore MD. The Agenda and Presentations
from the workshop are now available. Please click
here to read about the workshop and access the presentations.
HEI publishes report on Health
Effects of Particles in Rats with Features of Asthma or Bronchitis –
HEI investigators at Michigan
State University and the University of Michigan have just completed this
report on their study to evaluate the short-term effects of inhaling
concentrated ambient particles derived from the air in an area of Detroit,
Michigan on rats with some features of asthma and bronchitis. The study took
place in a Detroit neighborhood that has a high incidence of childhood asthma.
The investigators assessed two key features of asthma: airway inflammation and
hypersecretion of mucus in groups of rats that had been sensitized with the
allergen ovalbumin to induce some features of asthma; and in rats pretreated
with endotoxin to have some features of mild bronchitis.
to download Research Report 120, Effects of Concentrated
Ambient Particles on Normal and Hypersecretory Airways in Rats (including
the Commentary of the HEI Review Committee), or the HEI Statement (a short synopsis) for each report.
publishes Part III of the National Morbidity, Mortality and Air Pollution
Report 94, Part
III: Concentration–Response Curves and Thresholds for the 20 Largest US
on work by Dr Michael J Daniels and others (Dr Jonathan Samet, Principal
Investigator) of Johns Hopkins Bloomberg School of Public Health, Baltimore
latest report from the National Morbidity, Mortality, and Air Pollution Study examines the
question of whether there is a
threshold below which there does not appear to be an association between
particulate matter levels and mortality. It presents as well the
perspective of the HEI Review Committee on the results. Click here to download Report
94 Part III or the HEI Statement.
Now available: Special Report 15 – May 2004
Health Effects of Outdoor
Air Pollution in Developing Countries of Asia
first publication to come from HEI's Public Health and Air Pollution in
Asia (PAPA) Program was undertaken to help inform the Clean Air
Initiative for Asian Cities. This special report has identified and
summarized more than 135 studies of air pollution and health conducted across Asia.
In addition, it critically reviews for the first time a key subset of
these studies: 28 studies of daily mortality. To download the report or
an executive summary please click here.
HEI publishes report on Manganese
Transport into the Brain – January 2004
This report describes a study on manganese, a component of the fuel additive MMT.
Manganese is an essential nutrient and part of the daily diet, but also causes neurotoxic symptoms in workers that inhale
high concentrations. The
investigators studied the mechanism by which manganese may enter and leave the
brain of laboratory rats across its protective blood-brain barrier to try to understand whether
there are mechanisms that would allow or, alternatively, prevent accumulation
of manganese in the brain with prolonged exposure to low levels in the
environment. Click here to download
Report 119, Manganese Toxicokinetics at the Blood-Brain Barrier, or the HEI Statement (a short synopsis).
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» Dan Greenbaum
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Last updated November 08, 2004