The Oxford Chamber of Commerce is a business alliance of over 300 businesses. Started in 1979, the primary goal of the Chamber was to act as an advocate for small business. By the turn of the century, the Chamber has evolved into a much more comprehensive organization.

The Board of Directors and the Executive Director, along with many volunteers, strive to build a well-rounded benefits package for its members, to provide a library of information on various business topics, to organize workshops and seminars to assist small business and larger firms, to provide advertising opportunities as they become available, and to act as a liaison between Oxford area businesses and government.