Respiratory

Asthma

Asthma is a chronic condition that is currently estimated to affect more than 17 million Americans. Asthma accounts annually for more than 5,300 deaths, an estimated 3 million lost workdays for adults, and 10 million lost school days in children. Asthma ranks among the top ten prevalent conditions in the US, causing limitations of activity and health care costs that account for $12.7 billion annually.

Asthma is a chronic inflammatory disorder of the airways characterized by coughing, shortness of breath, and chest tightness. A variety of 'triggers' may initiate or worsen an asthma attack, including viral respiratory infections, exercise, and exposure to irritants. Typical treatments include both regularly taken medications to control the asthma and rescue treatments used for asthmatic attacks.

Entelos Asthma PhysioLab

Entelos Asthma PhysioLab is dynamic disease-simulation system that includes detailed modeling of the respiratory and immune systems. The asthma PhysioLab includes genetic, physiologic, environmental, and lifestyle factors that influence asthma, and represents therapeutic interventions currently on the market for the treatment of asthma.

Acknowledgements

Entelos would like to acknowledge the efforts of our Respiratory Advisory Board and Immunology Advisory Board for their help in the development and validation of Entelos Asthma PhysioLab:

  • Peter J. Barnes, MA, DM, DSc, FRCP
  • Jean Bousquet, MD
  • Stephen T. Holgate, MD, DSc, FRCP, FRCP(E), FRSA
  • Jay A. Nadel, MD
  • Abul Abbas, MBBS
  • Patrick G. Holt, DSc, FRCPath
  • Lewis L. Lanier, PhD