| gene |
geneID |
siRNA strand |
reference |
| AhR |
NM_001621 |
1416 - 1434 |
Mol Pharmacol 2003 Jun;63(6):1373-81 Aryl Hydrocarbon
Receptor Gene Silencing with Small Inhibitory RNA Differentially Modulates
Ah-Responsiveness in MCF-7 and HepG2 Cancer Cells. Abdelrahim
M, Smith R 3rd, Safe S. |
| ARNT |
|
|
Mol Pharmacol 2003 Jun;63(6):1373-81 Aryl Hydrocarbon
Receptor Gene Silencing with Small Inhibitory RNA Differentially Modulates
Ah-Responsiveness in MCF-7 and HepG2 Cancer Cells. Abdelrahim
M, Smith R 3rd, Safe S. |
| Prnp |
NM_011170 |
GCCCAGCAAACCAAAAACC-dTdT |
J
Cell Sci 2003 May 20
Specific inhibition of pathological prion protein accumulation
by small interfering RNAs.
Daude N, Marella M, Chabry J. |
| eRF1 |
|
ggagaucuggaagaucaagTT
guugaucuuccagaucuccTT |
RNA
2003 Jun;9(6):648-653
Stop codon suppression via inhibition of eRF1 expression.
Carnes J, Jacobson M, Leinwand L, Yarus M. |
| eRF1 |
|
uggcaccagcaugauaucaTT
ugauaucaugcuggugccaTT |
RNA
2003 Jun;9(6):648-653
Stop codon suppression via inhibition of eRF1 expression.
Carnes J, Jacobson M, Leinwand L, Yarus M. |
| eRF1 |
|
cacaagaagggucucaguuTT
aacugagacccuucuugugTT |
RNA
2003 Jun;9(6):648-653
Stop codon suppression via inhibition of eRF1 expression.
Carnes J, Jacobson M, Leinwand L, Yarus M. |
| MAPK14 |
BT006933 |
CCTACAGAGAACTGCGGTT-dTdT
ATGTGATTGGTCTGTTGGA-dTdT
TTCTCCGAGGTCTAAAGTA-dTdT
TAATTCACAGGGACCTAAA-dTdT
CCAGTGGCCGATCCTTATG-dTdT
TGCCTACTTTGCTCAGTAC-dTdT
GTCATCAGCTTTGTGCCAC-dTdT |
Nat
Biotechnol 2003 May 18
Expression profiling reveals off-target gene regulation
by RNAi.
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M,
Li B, Cavet G, Linsley PS.
|
| IGF1R |
NM_000875 |
GCTCACGGTCATTACCGAG-dTdT |
Nat
Biotechnol 2003 May 18
Expression profiling reveals off-target gene regulation
by RNAi.
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li
B, Cavet G, Linsley PS. |
| HBV |
|
cauuguucaccucaccauaTT
uauggugaggugaacaaugTT |
FEBS
Lett 2003 May 22;543(1-3):51-4
Short interfering RNA-directed inhibition of hepatitis
B virus replication.
Hamasaki K, Nakao K, Matsumoto K, Ichikawa T, Ishikawa H, Eguchi K. |
| GFP |
|
ggcuacguccaggagcgcacc
ugcgcuccuggacguagccTT |
FEBS
Lett 2003 May 22;543(1-3):51-4
Short interfering RNA-directed inhibition of hepatitis
B virus replication.
Hamasaki K, Nakao K, Matsumoto K, Ichikawa T, Ishikawa H, Eguchi K. |
| GTSE |
|
|
J
Biol Chem 2003 May 15
The cell-cycle regulated protein human GTSE-1 controls
DNA-damage induced apoptosis by affecting p53 function.
Monte M, Benetti R, Buscemi G, Sandy P, Del Sal G, Schneider C. |
| Chk1 |
|
|
Proc
Natl Acad Sci U S A 2003 May 13
Specificity of short interfering RNA determined through
gene expression signatures.
Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW. |
| AKT1 |
NM_005163 |
CGTGAGGCTCCCCTCAACA-dTdT |
Proc
Natl Acad Sci U S A 2003 May 13
Specificity of short interfering RNA determined through
gene expression signatures.
Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW. |
| Rb |
|
|
Proc
Natl Acad Sci U S A 2003 May 13
Specificity of short interfering RNA determined through
gene expression signatures.
Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW. |
| Plk1 |
NM_005030 |
CCAGTGGTTCGAGAGACAG-dTdT |
Proc
Natl Acad Sci U S A 2003 May 13
Specificity of short interfering RNA determined through
gene expression signatures.
Semizarov D, Frost L, Sarthy A, Kroeger P, Halbert DN, Fesik SW. |
| FADD |
aatgcgttctccttctctgtgcctgtc |
|
J
Biol Chem 2003 May 12
cFLIP-L inhibits p38 MAPK activation: An additional anti-apoptotic
mechanism in bile acid-mediated apoptosis.
Grambihler A, Higuchi H, Bronk SF, Gores GJ. |
| AR |
|
ccacaaauaccuggcuauaTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| AR |
|
aaauccauguaaugcagaaTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| HB-EGF |
|
gugaaguugggcaugacuaTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| HB-EGF |
|
uacaaggacuucugcauccTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| TGFÉø |
|
aacacugugaguggugccgTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| TGFÉø |
|
gaagcaggccaucaccgccTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| TACE |
|
aguuugcuuggcacaccuuTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| TACE |
|
aguaaggcccaggaguguuTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| TACE |
|
cauagagccacuuuggagaTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| ADAM12 |
|
ccucgcugcaaagaaugugTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| ADAM12 |
|
cguacgcggaauacuucgaTT |
EMBO
J 2003 May 15;22(10):2411-2421
TACE cleavage of proamphiregulin regulates GPCR-induced
proliferation and motility of cancer cells.
Gschwind A, Hart S, Fischer OM, Ullrich A. |
| human HCF-1 |
aaggagctcatcgtggtgttt |
|
EMBO
J 2003 May 15;22(10):2360-9
Proteolytic processing is necessary to separate and ensure
proper cell growth and cytokinesis functions of HCF-1.
Julien E, Herr W. |
| mouse HCF-1 |
aaggagcttatagtggtgttt |
|
EMBO
J 2003 May 15;22(10):2360-9
Proteolytic processing is necessary to separate and ensure
proper cell growth and cytokinesis functions of HCF-1.
Julien E, Herr W. |
| hamster HCF-1 |
aaggagctcatagtggtgttt |
|
EMBO
J 2003 May 15;22(10):2360-9
Proteolytic processing is necessary to separate and ensure
proper cell growth and cytokinesis functions of HCF-1.
Julien E, Herr W. |
| Akt1 |
|
ugcccuucuacaaccaggaTT
uccugguuguagaagggcaTT |
J
Biol Chem 2003 May 6
Use of RNA-interference-mediated gene silencing and adenoviral
overexpression to Elucidate the roles of AKT/PKB-isoforms in insulin actions.
Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi
K, Shiota H, Ebina Y. |
| Akt2 |
|
acucuuccacaucugagauTT
aucucagauguggaagaguTT |
J
Biol Chem 2003 May 6
Use of RNA-interference-mediated gene silencing and adenoviral
overexpression to Elucidate the roles of AKT/PKB-isoforms in insulin actions.
Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi
K, Shiota H, Ebina Y. |
| Akt3 |
|
auaauauuggagaggaagaTT
ucuuccucuccaauauuauTT |
J
Biol Chem 2003 May 6
Use of RNA-interference-mediated gene silencing and adenoviral
overexpression to Elucidate the roles of AKT/PKB-isoforms in insulin actions.
Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi
K, Shiota H, Ebina Y. |
| GFP |
|
cuggaguugucccaauuccTT
agaauugggacaacuccagTT |
J
Biol Chem 2003 May 6
Use of RNA-interference-mediated gene silencing and adenoviral
overexpression to Elucidate the roles of AKT/PKB-isoforms in insulin actions.
Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi
K, Shiota H, Ebina Y. |
| p73 |
|
|
Cancer
Cell 2003 Apr;3(4):403-10
Chemosensitivity linked to p73 function.
Irwin MS, Kondo K, Marin MC, Cheng LS, Hahn WC, Kaelin WG. |
| TRPC1 |
X89066 |
AAGCTTTTCTTGCTGGCGTGC-dTdT |
Biochem
J 2003 Apr 29
Evidence that TRPC1 forms a Ca 2+ permeable channel linked
to the regulation of cell volume in liver cells obtained using siRNA targeted
against TRPC1.
Chen J, Barritt GJ. |
| HDAC6 |
NM_006044 |
AAGACCTAATCGTGGGACTGC-dTdT |
Mol
Cell 2003 Apr;11(4):1043-54
p300 Transcriptional Repression Is Mediated by SUMO Modification.
Girdwood D, Bumpass D, Vaughan OA, Thain A, Anderson LA, Snowden AW,
Garcia-Wilson E, Perkins ND, Hay RT. |
| Y14 |
AF299118 |
AACGCTCTGTTGAAGGCTGGA-dT-dT |
Mol
Cell 2003 Apr;11(4):939-49
Y14 and hUpf3b Form an NMD-Activating Complex.
Gehring NH, Neu-Yilik G, Schell T, Hentze MW, Kulozik AE. |
| CRIF1 |
aagaacgcgaatggtacccga |
|
J
Biol Chem 2003 Apr 25
CR6 interacting factor 1 (CRIF1) interacts with Gadd45
family proteins and modulates the cell cycle.
Chung H, Yi YW, Jung NC, Kim D, Suh JM, Kim H, Park KC, Song JH, Kim
DW, Hwang ES, Yoon SH, Bae YS, Kim JM, Bae I, Shong M. |
| CRIF1 |
aagatgccacagatgattgtg |
|
J
Biol Chem 2003 Apr 25
CR6 interacting factor 1 (CRIF1) interacts with Gadd45
family proteins and modulates the cell cycle.
Chung H, Yi YW, Jung NC, Kim D, Suh JM, Kim H, Park KC, Song JH, Kim
DW, Hwang ES, Yoon SH, Bae YS, Kim JM, Bae I, Shong M. |
| CRIF1 |
aagcgcctcaaggaggaaaaa |
|
J
Biol Chem 2003 Apr 25
CR6 interacting factor 1 (CRIF1) interacts with Gadd45
family proteins and modulates the cell cycle.
Chung H, Yi YW, Jung NC, Kim D, Suh JM, Kim H, Park KC, Song JH, Kim
DW, Hwang ES, Yoon SH, Bae YS, Kim JM, Bae I, Shong M. |
| CRIF1 |
aaaaacagaaacggaagaagg |
|
J
Biol Chem 2003 Apr 25
CR6 interacting factor 1 (CRIF1) interacts with Gadd45
family proteins and modulates the cell cycle.
Chung H, Yi YW, Jung NC, Kim D, Suh JM, Kim H, Park KC, Song JH, Kim
DW, Hwang ES, Yoon SH, Bae YS, Kim JM, Bae I, Shong M. |
| hDAB2 |
|
|
FEBS
Lett 2003 Apr 24;541(1-3):21-7
Disabled-2 small interfering RNA modulates cellular adhesive
function and MAPK activity during megakaryocytic differentiation of K562
cells.
Tseng CP, Huang CL, Huang CH, Cheng JC, Stern A, Tseng CH, Chiu DT. |
| RhoA |
aagaaaaagtccgggtgccttcctgtctc |
|
Dev
Dyn 2003 May;227(1):35-47
RhoA is highly up-regulated in the process of early heart
development of the chick and important for normal embryogenesis.
Kaarbo M, Crane DI, Murrell WG. |
| p27Kip1 |
aagtacgagtggcaagaggtg |
|
J
Biol Chem 2003 Apr 16
The role of cyclin-dependent kinase inhibitor p27Kip1 in
anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.
Le XF, Claret FX, Lammayot A, Tian L, Deshpande D, LaPushin R, Tari AM,
Bast RC Jr. |
| p27Kip1 |
aagcactgcagagacatggaa |
|
J
Biol Chem 2003 Apr 16
The role of cyclin-dependent kinase inhibitor p27Kip1 in
anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.
Le XF, Claret FX, Lammayot A, Tian L, Deshpande D, LaPushin R, Tari AM,
Bast RC Jr. |
| hILK |
|
|
J
Biol Chem 2003 Apr 8
Conditional knock-out of integrin-linked kinase (ILK) demonstrates
an essential role in PKB/Akt activation.
Troussard AA, Mawji NN, Ong C, Mui A, St Arnaud R, Dedhar S. |
| beta-catenin |
|
agcugauauugauggacagTT |
Clin
Cancer Res 2003 Apr;9(4):1291-300
Small Interfering RNAs Directed against beta-Catenin Inhibit
the in Vitro and in Vivo Growth of Colon Cancer Cells.
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. |
| beta-catenin |
|
caguugugguuaagcucuuAC |
Clin
Cancer Res 2003 Apr;9(4):1291-300
Small Interfering RNAs Directed against beta-Catenin Inhibit
the in Vitro and in Vivo Growth of Colon Cancer Cells.
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. |
| APC |
|
gcaacagaagcagagagguTT |
Clin
Cancer Res 2003 Apr;9(4):1291-300
Small Interfering RNAs Directed against beta-Catenin Inhibit
the in Vitro and in Vivo Growth of Colon Cancer Cells.
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. |
| NF-kappaB |
|
gcccuaucccuuuacgucaTT |
Clin
Cancer Res 2003 Apr;9(4):1291-300
Small Interfering RNAs Directed against beta-Catenin Inhibit
the in Vitro and in Vivo Growth of Colon Cancer Cells.
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. |
| HTLV-1 Tax |
|
gauggacgcguuaucggcuTT |
Clin
Cancer Res 2003 Apr;9(4):1291-300
Small Interfering RNAs Directed against beta-Catenin Inhibit
the in Vitro and in Vivo Growth of Colon Cancer Cells.
Verma UN, Surabhi RM, Schmaltieg A, Becerra C, Gaynor RB. |
| murine RASA1 |
NM_002890 |
AAGATGAAGCCACTACCCTATTT-dTdT |
Nat
Biotechnol 2003 Apr 7
Transgenic RNA interference in ES cell-derived embryos
recapitulates a genetic null phenotype.
Kunath T, Gish G, Lickert H, Jones N, Pawson T, Rossant J. |
| hRASA1 |
|
|
Nat
Biotechnol 2003 Apr 7
Transgenic RNA interference in ES cell-derived embryos
recapitulates a genetic null phenotype.
Kunath T, Gish G, Lickert H, Jones N, Pawson T, Rossant J. |
| Chk1 |
aactgaagaagcagtcgcagt |
|
J
Biol Chem 2003 Apr 3
Chk1 mediates S and G2 arrests through Cdc25Adegradation
in response to DNA damaging agents.
Xiao Z, Chen Z, Gunasekera AH, Sowin TJ, Rosenberg SH, Fesik S, Zhang
H. |
| Chk1 scramble |
aacaagtgaagcagtcgcagt |
|
J
Biol Chem 2003 Apr 3
Chk1 mediates S and G2 arrests through Cdc25Adegradation
in response to DNA damaging agents.
Xiao Z, Chen Z, Gunasekera AH, Sowin TJ, Rosenberg SH, Fesik S, Zhang
H. |
| p120(ctn) |
|
|
Gastroenterology
2003 Apr;124(4):949-60
Up-regulation, nuclear import, and tumor growth stimulation
of the adhesion protein p120 in pancreatic cancer.
Mayerle J, Friess H, Buchler MW, Schnekenburger J, Weiss FU, Zimmer KP,
Domschke W, Lerch MM. |
| ATM |
|
TGTATCAGCCTCAACACAAGCCTCCAGGCAG-dTdT |
Cancer
Res 2003 Apr 1;63(7):1550-4
Enhanced Radiation and Chemotherapy-mediated Cell Killing
of Human Cancer Cells by Small Inhibitory RNA Silencing of DNA Repair Factors.
Collis SJ, Swartz MJ, Nelson WG, DeWeese TL. |
| ATR |
NM_001184 |
CCATGATCCCCGCCCTGCGGGAGCTGGGCAG-dTdT |
Cancer
Res 2003 Apr 1;63(7):1550-4
Enhanced Radiation and Chemotherapy-mediated Cell Killing
of Human Cancer Cells by Small Inhibitory RNA Silencing of DNA Repair Factors.
Collis SJ, Swartz MJ, Nelson WG, DeWeese TL. |
| DNA-PKcs |
|
|
Cancer
Res 2003 Apr 1;63(7):1550-4
Enhanced Radiation and Chemotherapy-mediated Cell Killing
of Human Cancer Cells by Small Inhibitory RNA Silencing of DNA Repair Factors.
Collis SJ, Swartz MJ, Nelson WG, DeWeese TL. |
| telomerase |
|
uugucuaacccuaacugagTT
cucaguuaggguuagacaaTT |
Mol
Cancer Ther 2003 Mar;2(3):209-16
Inhibition of telomerase activity in human cancer cells
by RNA interference.
Kosciolek BA, Kalantidis K, Tabler M, Rowley PT. |
| telomerase |
|
ggcuucuccggaggcacccTT
gggugccuccggagaagccTT |
Mol
Cancer Ther 2003 Mar;2(3):209-16
Inhibition of telomerase activity in human cancer cells
by RNA interference.
Kosciolek BA, Kalantidis K, Tabler M, Rowley PT. |
| hTERT |
|
caagguggaugugacgggcTT
gcccgucacauccacguugTT |
Mol
Cancer Ther 2003 Mar;2(3):209-16
Inhibition of telomerase activity in human cancer cells
by RNA interference.
Kosciolek BA, Kalantidis K, Tabler M, Rowley PT. |
| Chk1 |
|
gaagcagucgcagugaagaTT
ucuucacugcgacugguucTT |
J
Biol Chem 2003 Mar 24
Questioning the role of Chk2 in the p53 DNA Damage Response.
Ahn J, Urist M, Prives C. |
| Chk2 |
|
gaaccugaggaccaagaac
guucuugguccucagguuc |
J
Biol Chem 2003 Mar 24
Questioning the role of Chk2 in the p53 DNA Damage Response.
Ahn J, Urist M, Prives C. |
| TNF |
|
gugccuaugucucagccucuu |
Mol
Biol 2003 Apr 4;327(4):761-6
Gene Silencing by Systemic Delivery of Synthetic siRNAs
in Adult Mice.
Sorensen DR, Leirdal M, Sioud M. |
| TNF |
|
gaucaucuucucaaaauucuu |
Mol
Biol 2003 Apr 4;327(4):761-6
Gene Silencing by Systemic Delivery of Synthetic siRNAs
in Adult Mice.
Sorensen DR, Leirdal M, Sioud M. |
| TNF |
|
gacaaccaacuaguggugcuu |
Mol
Biol 2003 Apr 4;327(4):761-6
Gene Silencing by Systemic Delivery of Synthetic siRNAs
in Adult Mice.
Sorensen DR, Leirdal M, Sioud M. |
| TNF |
|
ggagaaagucaaccuccucuu |
Mol
Biol 2003 Apr 4;327(4):761-6
Gene Silencing by Systemic Delivery of Synthetic siRNAs
in Adult Mice.
Sorensen DR, Leirdal M, Sioud M. |
| TNF |
|
ggccuuccuaccuucagacuu |
Mol
Biol 2003 Apr 4;327(4):761-6
Gene Silencing by Systemic Delivery of Synthetic siRNAs
in Adult Mice.
Sorensen DR, Leirdal M, Sioud M. |
| cyclin G |
|
aagucaguugccaaugggacaTT |
Oncogene
2003 Mar 20;22(11):1678-87
Modulation of p53 and p73 levels by cyclin G: implication
of a negative feedback regulation.
Ohtsuka T, Ryu H, Minamishima YA, Ryo A, Lee SW. |
| lamin A/C |
aactggacttccagaagaaca |
|
Proc
Natl Acad Sci U S A 2003 Jan 7;100(1):235-40
Clearance of replicating hepatitis C virus replicon RNAs
in cell culture by small interfering RNAs.
Randall G, Grakoui A, Rice CM. |
| HCV |
aacctcaaagaaaaaccaaac |
|
Proc
Natl Acad Sci U S A 2003 Jan 7;100(1):235-40
Clearance of replicating hepatitis C virus replicon RNAs
in cell culture by small interfering RNAs.
Randall G, Grakoui A, Rice CM. |
| HCV-Con1 |
aaggtgcttgtggatattttg |
|
Proc
Natl Acad Sci U S A 2003 Jan 7;100(1):235-40
Clearance of replicating hepatitis C virus replicon RNAs
in cell culture by small interfering RNAs.
Randall G, Grakoui A, Rice CM. |
| HCV-C/LB |
aaggcgcttgtggacattctg |
|
Proc
Natl Acad Sci U S A 2003 Jan 7;100(1):235-40
Clearance of replicating hepatitis C virus replicon RNAs
in cell culture by small interfering RNAs.
Randall G, Grakoui A, Rice CM. |
| GABP |
aaggatgctcgagactgtatt |
|
Biol Chem 2003 Mar 4
Purification and mass spectrometric identification of GABP
as the functional pituitary Ets factor binding to the basal transcription
element of the prolactin promoter.
Schweppe RE, Melton AA, Brodsky KS, Aveline LD, Resing KA, Ahn NG, Gutierrez-Hartmann
A. |
| GABP |
aacatatggcaagccctcaat |
|
Biol Chem 2003 Mar 4
Purification and mass spectrometric identification of GABP
as the functional pituitary Ets factor binding to the basal transcription
element of the prolactin promoter.
Schweppe RE, Melton AA, Brodsky KS, Aveline LD, Resing KA, Ahn NG, Gutierrez-Hartmann
A. |
| MDC1 |
|
gucucccagaagacagugaTT |
Nature
2003 Feb 27;421(6926):961-6
MDC1 is a mediator of the mammalian DNA damage checkpoint.
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ. |
| MDC1 |
|
acaguuguccccacagcccTT |
Nature
2003 Feb 27;421(6926):961-6
MDC1 is a mediator of the mammalian DNA damage checkpoint.
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ. |
| EMCV-IRES |
|
cgucuaggcccccgaaccacTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| NS3 |
|
cucguccccuccggccguaccTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| NS3 |
|
gggggggaggcaccucauuuuTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| NS5b |
|
ggagaugaaggcgaaggcgucTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| NS5b |
|
gacacugagacaccaauugacTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| NS5b |
|
gggcagaacugcggcuaucgcTT |
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference blocks gene expression and RNA synthesis
from hepatitis C replicons propagated in human liver cells.
Wilson JA, Jayasena S, Khvorova A, Sabatinos S, Rodrigue-Gervais IG,
Arya S, Sarangi F, Harris-Brandts M, Beaulieu S, Richardson CD. |
| influenza virus |
|
|
Proc
Natl Acad Sci U S A 2003 Feb 19
RNA interference of influenza virus production by directly
targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription.
Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J. |
| GFP |
|
p-ggcuacguccaggagcgcaTT
p-ugcgcuccuggacguagccTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| GFP |
|
p-ggcuacguccaggagcgcacc
p-ugcgcuccuggacguagccuu |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-aagccgaaugucgcagaacTT
p-guucugcgacauucggcuuTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-auacaucccgagaauugcuTT
p-agcaauucucgggauguauTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-aucgccuaugguuguugacTT
p-gucaacaaccauaggcgauTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-ggauuauaucaaggaggccTT
p-ggccuccuugauauaauccTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-agccgaaugucgcagaaccTT
p-gguucugcgacauucggcuTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| Fas |
|
p-gugcaagugcaaaccagacTT
p-gucugguuugcacuugcacTT |
Nat
Med 2003 Feb 10
RNA interference targeting Fas protects mice from fulminant
hepatitis.
Song E, Lee SK, Wang J, Ince N, Ouyang N, Min J, Chen J, Shankar P, Lieberman
J. |
| insulin recepter |
|
tataccatgaattccagcaacTT |
J
Biol Chem 2003 Feb 3
Cdc42 is a Rho GTPase family member which can mediate insulin
signaling to glucose transport in 3T3-L1 adipocytes.
Usui I, Imamura T, Huang J, Satoh H, Olefsky JM. |
| SMRT |
|
cgagaguucucgcuggacuTT |
J
Biol Chem 2003 Feb 3
Cdc42 is a Rho GTPase family member which can mediate insulin
signaling to glucose transport in 3T3-L1 adipocytes.
Usui I, Imamura T, Huang J, Satoh H, Olefsky JM. |
| cdc42 |
|
guuauccacagacagauguTT |
J
Biol Chem 2003 Feb 3
Cdc42 is a Rho GTPase family member which can mediate insulin
signaling to glucose transport in 3T3-L1 adipocytes.
Usui I, Imamura T, Huang J, Satoh H, Olefsky JM. |
| p75NTR |
|
AAGGAGACATGTTCCACAGGCAT-dtdT |
Biochem
Biophys Res Commun 2003 Feb 14;301(3):804-9
Functional inhibition of the p75 receptor using a small
interfering RNA.
Higuchi H, Yamashita T, Yoshikawa H, Tohyama M. |
| EGFP |
aagctgaccctgaagttcatc |
|
Biochem
Biophys Res Commun 2003 Feb 14;301(3):704-10
Mammalian actin binding protein 1 is essential for endocytosis
but not lamellipodia formation: functional analysis by RNA interference.
Mise-Omata S, Montagne B, Deckert M, Wienands J, Acuto O |
| hDok2 |
aaagaaatggcgccgcttcgg |
|
Biochem
Biophys Res Commun 2003 Feb 14;301(3):704-10
Mammalian actin binding protein 1 is essential for endocytosis
but not lamellipodia formation: functional analysis by RNA interference.
Mise-Omata S, Montagne B, Deckert M, Wienands J, Acuto O |
| hmAbp1 |
aagtccccgaccgactgggct |
|
Biochem
Biophys Res Commun 2003 Feb 14;301(3):704-10
Mammalian actin binding protein 1 is essential for endocytosis
but not lamellipodia formation: functional analysis by RNA interference.
Mise-Omata S, Montagne B, Deckert M, Wienands J, Acuto O. |
| mATM |
|
aaugucuuugaguaguaugTT
cauacuacucaaagacauuTT |
J
Biol Chem 2003 Jan 21
Single-stranded DNA induces ATM/p53-dependent DNA damage
and apoptotic signals.
Nur-E-Kamal A, Tsai-Kun L, Zhang A, Qi H, Hars E, Liu LF. |
| TonEBP |
|
|
J
Am Soc Nephrol 2003 Feb;14(2):283-8
Silencing of TonEBP/NFAT5 transcriptional activator by
RNA interference.
Na KY, Woo SK, Lee SD, Kwon HM. |
| hMLK3 |
aagaccctgaagatcaccgactt |
|
Mol
Biol Cell 2003 Jan;14(1):156-72
A New Identity for MLK3 as an NIMA-related, Cell Cycle-regulated
Kinase That Is Localized near Centrosomes and Influences Microtubule Organization.
Swenson KI, Winkler KE, Means AR. |
| xMiRP2 |
aagggaaccacacggacgcca |
|
J
Biol Chem 2003 Jan 15
RNAi reveals endogenous Xenopus MiRPs govern mammalian
K+ channel function in oocyte expression studies.
Anantharam A, Lewis A, Panaghie G, Gordon E, McCrossan ZA, Lerner DJ,
Abbott GW. |
| p110É¿ |
|
aaauuccagugguucauuccaTT
uggaaugaaccacuggaauuuTT |
Nucleic
Acids Res 2003 Jan 15;31(2):670-82
Functional studies of the PI(3)-kinase signalling pathway
employing synthetic and expressed siRNA.
Czauderna F, Fechtner M, Aygun H, Arnold W, Klippel A, Giese K, Kaufmann
J. |
| p110 |
|
auauuccugagcuugauaccaTT
ugguaucaagcucaggaauauTT |
Nucleic
Acids Res 2003 Jan 15;31(2):670-82
Functional studies of the PI(3)-kinase signalling pathway
employing synthetic and expressed siRNA.
Czauderna F, Fechtner M, Aygun H, Arnold W, Klippel A, Giese K, Kaufmann
J. |
| akt1 |
|
acgaggggaguacaucaagacaa-
aagucuugauguacuccccucgu |
Nucleic
Acids Res 2003 Jan 15;31(2):670-82
Functional studies of the PI(3)-kinase signalling pathway
employing synthetic and expressed siRNA.
Czauderna F, Fechtner M, Aygun H, Arnold W, Klippel A, Giese K, Kaufmann
J. |
| akt2 |
|
cuccuucauuggguacaaggaaaa-
aaaaaaaauccuuguacccaaugaaggag |
Nucleic
Acids Res 2003 Jan 15;31(2):670-82
Functional studies of the PI(3)-kinase signalling pathway
employing synthetic and expressed siRNA.
Czauderna F, Fechtner M, Aygun H, Arnold W, Klippel A, Giese K, Kaufmann
J. |
| hTF167i |
|
gcgcuucaggcacuacaaaua
uuuguagugccugaagcgccg |
Nucleic
Acids Res 2003 Jan 15;31(2):589-95
Tolerance for mutations and chemical modifications in a
siRNA.
Amarzguioui M, Holen T, Babaie E, Prydz H. |
| EGFP |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| DsRed |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| firefly luc |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| human dicer |
NM_153402 |
ATTGATGTCTACCTCTATGAAGT-dTdT |
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| mouse dicer |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| human eIF2C4 |
NM_153177 |
TATGGTGCGGCACTTCAAGATGC-dTdT |
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| human eIF2C3 |
NM_153402 |
ATTGATGTCTACCTCTATGAAGT-dTdT |
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| mouse eIF2C3 |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| human eIF2C4 |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| mouse eIF2C4 |
|
|
Curr
Biol 2003 Jan 8;13(1):41-6
Short-Interfering-RNA-Mediated Gene Silencing in Mammalian
Cells Requires Dicer and eIF2C Translation Initiation Factors.
Doi N, Zenno S, Ueda R, Ohki-Hamazaki H, Ui-Tei K, Saigo K. |
| mPEN-1 |
aaggctatgtttggcgctcag |
|
J
Biol Chem 2003 Jan 8
PEN-2 and APH-1 coordinately regulate proteolytic processing
of presenilin 1.
Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, Thinakaran G, Kim TW, Yu
G, Xu H. |
| APH-1a |
aaggcagatgagggcttagca |
|
J
Biol Chem 2003 Jan 8
PEN-2 and APH-1 coordinately regulate proteolytic processing
of presenilin 1.
Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, Thinakaran G, Kim TW, Yu
G, Xu H. |
| hPEN-1 |
aaaggctatgtctggcgctca |
|
J
Biol Chem 2003 Jan 8
PEN-2 and APH-1 coordinately regulate proteolytic processing
of presenilin 1.
Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, Thinakaran G, Kim TW, Yu
G, Xu H. |
| POSH |
|
gucagacuucuggauggcaTC |
EMBO
J 2003 Jan 15;22(2):252-61
POSH acts as a scaffold for a multiprotein complex that
mediates JNK activation in apoptosis.
Xu Z, Kukekov NV, Greene LA. |
| OPA1 |
AB011139 |
AAGTTATCAGTCTGAGCCAGG-dTdT |
J Biol Chem 2002 Dec 31 Loss of OPA1 perturbates
the mitochondrial inner membrane structure and integrity, leading to cytochrome
c release and apoptosis. Olichon A, Baricault L, Gas N,
Guillou E, Valette A, Belenguer P, Lenaers G. |
| kinesin Eg5 |
|
|
Biotechniques 2002 Dec;33(6):1244-8 Targeting the
kinesin Eg5 to monitor siRNA transfection in mammalian cells.
Weil D, Garcon L, Harper M, Dumenil D, Dautry F, Kress M. |
| CD54 |
|
|
J
Biol Chem 2002 Dec 23
Efficient reduction of target RNA's by siRNA and RNase
H dependent antisense agents: A comparative analysis.
Vickers TA, Koo S, Bennett CF, Crooke ST, Dean NM, Baker BF. |
| PTEN |
|
|
J
Biol Chem 2002 Dec 23
Efficient reduction of target RNA's by siRNA and RNase
H dependent antisense agents: A comparative analysis.
Vickers TA, Koo S, Bennett CF, Crooke ST, Dean NM, Baker BF. |
| DLP1 |
|
|
J
Biol Chem 2002 Dec 23
The dynamin-like protein DLP1 is involved inperoxisomal
fission.
Koch A, Thiemann M, Grabenbauer M, Yoon Y, McNiven MA, Schrader M. |
| DNMT1 |
aagcatgagcaccgttctcc |
|
Nat
Genet 2002 Dec 23
DNMT1 is required to maintain CpG methylation and aberrant
gene silencing in human cancer cells.
Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod
AR. |
| CPI-17 |
aagtggatcgacggatgcttg |
|
Neuron
2002 Dec 19;36(6):1145-1158
Cerebellar Long-Term Synaptic Depression Requires PKC-Mediated
Activation of CPI-17, a Myosin/Moesin Phosphatase Inhibitor.
Eto M, Bock R, Brautigan DL, Linden DJ. |
| PHI-1 |
|
|
Neuron
2002 Dec 19;36(6):1145-1158
Cerebellar Long-Term Synaptic Depression Requires PKC-Mediated
Activation of CPI-17, a Myosin/Moesin Phosphatase Inhibitor.
Eto M, Bock R, Brautigan DL, Linden DJ. |
| PLC-gamma1 |
aaacaaccggctcttcgtc |
|
Cell
2002 Nov 15;111(4):529-41
Phospholipase C-gamma is required for agonist-induced Ca2+
entry.
Patterson RL, van Rossum DB, Ford DL, Hurt KJ, Bae SS, Suh PG, Kurosaki
T, Snyder SH, Gill DL. |
| PCL-gamma2 |
aatcctgacttccgggaaa |
|
Cell
2002 Nov 15;111(4):529-41
Phospholipase C-gamma is required for agonist-induced Ca2+
entry.
Patterson RL, van Rossum DB, Ford DL, Hurt KJ, Bae SS, Suh PG, Kurosaki
T, Snyder SH, Gill DL. |
| RasGRP4 |
|
|
J
Biol Chem 2002 Dec 18
RasGRP4 regulates the expression of prostaglandin D2 in
human and rat mast cell lines.
Li L, Yang Y, Stevens RL. |
| epicardin/capsulin/Pod-1 |
aaggccttctccagactcaag |
|
J
Biol Chem 2002 Dec 19
Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1
suppresses differentiation by negative regulation of transcription.
Funato N, Ohyama K, Kuroda T, Nakamura M. |
| DP97 |
|
gaagaagucuggaggcuucTT
gaagccuccagacuucuucTT |
J
Biol Chem 2002 Dec 3
Regulation of nuclear receptor transcriptional activity
by a novel DEAD box RNA helicase (DP97).
Rajendran RR, Nye AC, Frasor J, Balsara RD, Martini PG, Katzenellenbogen
BS. |
| HuR |
|
guugaaucugcaaaacuuaTT
uaaguuuugcagauucaacTT |
Genes
Dev 2002 Dec 1;16(23):3087-99
ELAV/Hu proteins inhibit p27 translation via an IRES element
in the p27 5'UTR.
Kullmann M, Gopfert U, Siewe B, Hengst L. |
| HuR |
|
ugugaaagugauccgcgacTT
gucgcggaucacuuucacaTT |
Genes
Dev 2002 Dec 1;16(23):3087-99
ELAV/Hu proteins inhibit p27 translation via an IRES element
in the p27 5'UTR.
Kullmann M, Gopfert U, Siewe B, Hengst L. |
| rat MafK |
aaggaggaggtaactcggctg |
|
J
Neurosci 2002 Oct 15;22(20):8971-80
The basic region and leucine zipper transcription factor
MafK is a new nerve growth factor-responsive immediate early gene that regulates
neurite outgrowth.
Torocsik B, Angelastro JM, Greene LA. |
| PP2A |
aaatgtgcaagaggttcgttg |
augugcaagagguucguugTT
caacgaaccucuugcacauTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| PP2A |
aatgtctgcgaaagtatggga |
ugucugcgaaaguaugggaTT
ucccauacuuucgcagacaTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| PP2A |
aattggtgtcatgatcggaat |
uuggugucaugaucggaauTT
auuccgaucaugacaccaaTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| PP4 |
aaggccagagagatcttggta |
ggccagagagaucuugguaTT
uaccaagaucucucuggccTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| PP4 |
aatcgaccgaaagcaagaggt |
ucgaccgaaagcaagagguTT
accucuugcuuucggucgaTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| PP4 |
aagtggcacttcaatgagacg |
guggcacuucaaugagacgTT
cgucucauugaagugccacTT |
J
Biol Chem 2002 Nov 19
Protein phosphatase 2A and phosphoprotein SET regulate
androgen production by P450c17.
Pandey AV, Mellon SH, Miller WL. |
| DNA-PKcs |
|
gaucgcaccuuacucuguuTT
aacagaguaaggugcgaucTT |
Cancer
Res 2002 Nov 15;62(22):6400-4
Silencing Expression of the Catalytic Subunit of DNA-dependent
Protein Kinase by Small Interfering RNA Sensitizes Human Cells for Radiation-induced
Chromosome Damage, Cell Killing, and Mutation.
Peng Y, Zhang Q, Nagasawa H, Okayasu R, Liber HL, Bedford JS. |
| DNA-PKcs |
|
cuuuaugguggccauggagTT
cuccauggccaccauaaagTT |
Cancer
Res 2002 Nov 15;62(22):6400-4
Silencing Expression of the Catalytic Subunit of DNA-dependent
Protein Kinase by Small Interfering RNA Sensitizes Human Cells for Radiation-induced
Chromosome Damage, Cell Killing, and Mutation.
Peng Y, Zhang Q, Nagasawa H, Okayasu R, Liber HL, Bedford JS. |
| CD4 |
|
|
Small interfering RNA-mediated gene silencing in T lymphocytes.
J Immunol. 2002 Nov 15;169(10):5754-60.
http://www.jimmunol.org/cgi/content/full/169/10/5754
McManus MT, Haines BB, Dillon CP, Whitehurst CE, van Parijs
L, Chen J, Sharp PA.
|
| CD8alpha |
|
|
Small interfering RNA-mediated gene silencing in T lymphocytes.
J Immunol. 2002 Nov 15;169(10):5754-60.
McManus MT, Haines BB, Dillon CP, Whitehurst CE, van Parijs
L, Chen J, Sharp PA.
|
| p21Cip1/Waf1 |
aacggtggaactttgacttcg |
|
Genes
Dev 2002 Nov 15;16(22):2923-34
Cdk4 disruption renders primary mouse cells resistant to
oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X, Ray D, Aziyu A, Christov K, Boiko AD, Gudkov AV, Kiyokawa H. |
| KLF4 |
|
|
J
Biol Chem 2002 Nov 8
Kruppel-like factor 4 mediates p53-dependent G1/S cell
cycle arrest in response to DNA damage.
Yoon HS, Chen X, Yang VW. |
| luciferase |
|
ucgaaguauuccgcguacgug
cguacgcggaauacuucgauu |
Mol
Cell 2002 Sep;10(3):537-48
Evidence that siRNAs Function as Guides, Not Primers, in
the Drosophila and Human RNAi Pathways.
Schwarz DS, Hutvagner G, Haley B, Zamore PD. |
| GFP |
|
gcagcacgacuucuucaagTT
cuugaagaagucgugcugcTT |
Mol
Cell 2002 Sep;10(3):549-61
RNAi in Human Cells. Basic Structural and Functional Features
of Small Interfering RNA.
Chiu YL, Rana TM. |
| RFP |
|
gugggagcgcgugaugaacTT
guucaucacgcgcucccacTT |
Mol
Cell 2002 Sep;10(3):549-61
RNAi in Human Cells. Basic Structural and Functional Features
of Small Interfering RNA.
Chiu YL, Rana TM. |
| ADAR2 |
|
uacaugagugaucguggccuu
ggccacgaucacucauguauu |
Proc
Natl Acad Sci U S A 2002 Oct 24
Replicating hepatitis delta virus RNA is edited in the
nucleus by the small form of ADAR1.
Wong SK, Lazinski DW. |
| ADAR1 |
|
ccagcacagcggagugguauu
uaccacuccgcugugcugguu |
Proc
Natl Acad Sci U S A 2002 Oct 24
Replicating hepatitis delta virus RNA is edited in the
nucleus by the small form of ADAR1.
Wong SK, Lazinski DW. |
| ADAR1 |
|
gacccgcggaguuucccguuu
acgggaaacuccgcgggucug |
Proc
Natl Acad Sci U S A 2002 Oct 24
Replicating hepatitis delta virus RNA is edited in the
nucleus by the small form of ADAR1.
Wong SK, Lazinski DW. |
| hACBP |
|
|
Biochem
J 2002 Oct 23
Acyl-CoA binding protein is an essential protein in mammalian cell lines.
Faergeman NJ, Knudsen J. |
| bcr-abl |
|
gcagaguucaaaagcccuuTT
aagggcuuuugaacucugcTT |
Blood
2002 Sep 26
Specific inhibition of bcr-abl gene expression by small
interfering RNA.
Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M. |
| bcr-abl |
|
agcagaguucaaaagcccuTT
agggcuuuugaacucugcuTT |
Blood
2002 Sep 26
Specific inhibition of bcr-abl gene expression by small
interfering RNA.
Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M. |
| luciferase |
|
cauucuauccucuagaggaugTT |
J
Immunol 2002 Nov 1;169(9):5196-5201
Inhibition of HIV-1 Infection by Small Interfering RNA-Mediated
RNA Interference.
Capodici J, Kariko K, Weissman D. |
| HXB2 |
|
gagaaccaaggggaagugacaTT |
J
Immunol 2002 Nov 1;169(9):5196-5201
Inhibition of HIV-1 Infection by Small Interfering RNA-Mediated
RNA Interference.
Capodici J, Kariko K, Weissman D. |
| hSPK1 |
|
gggcaaggccttgcagctcTT |
Mol
Cell Biol 2002 Nov 15;22(22):7758-7768
Sphingosine Kinase Mediates Vascular Endothelial Growth
Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases.
Shu X, Wu W, Mosteller RD, Broek D. |
| |
|
|
|
| |
|
|
McManus MT, Haines BB, Dillon CP, Whitehurst CE, van Parijs L, Chen J,
Sharp PA.
Related Articles, Links
Small interfering RNA-mediated gene s |
| hSPK2 |
|
gccaggccccggggtggccTT |
Mol
Cell Biol 2002 Nov 15;22(22):7758-7768
Sphingosine Kinase Mediates Vascular Endothelial Growth
Factor-Induced Activation of Ras and Mitogen-Activated Protein Kinases.
Shu X, Wu W, Mosteller RD, Broek D. |
| GS15 |
|
|
Mol
Biol Cell 2002 Oct;13(10):3493-3507
GS15 Forms a SNARE Complex with Syntaxin 5, GS28, and Ykt6
and Is Implicated in Traffic in the Early Cisternae of the Golgi Apparatus.
Xu Y, Martin S, James DE, Hong W. |
| GS15 |
|
|
Mol
Biol Cell 2002 Oct;13(10):3493-3507
GS15 Forms a SNARE Complex with Syntaxin 5, GS28, and Ykt6
and Is Implicated in Traffic in the Early Cisternae of the Golgi Apparatus.
Xu Y, Martin S, James DE, Hong W. |
| BRF1 |
|
caagaugcucaacuauaguTT
acuauaguugagcaucuugTT |
EMBO
J 2002 Sep 2;21(17):4709-18
Functional cloning of BRF1, a regulator of ARE-dependent
mRNA turnover.
Stoecklin G, Colombi M, Raineri I, Leuenberger S, Mallaun M, Schmidlin
M, Gross B, Lu M, Kitamura T, Moroni C. |
| murineIL-3 |
|
ccagaacguugaauugcagTT
cugcaauucaacguucuggTT |
EMBO
J 2002 Sep 2;21(17):4709-18
Functional cloning of BRF1, a regulator of ARE-dependent
mRNA turnover.
Stoecklin G, Colombi M, Raineri I, Leuenberger S, Mallaun M, Schmidlin
M, Gross B, Lu M, Kitamura T, Moroni C. |
| hERAAP |
agctagtaatggagactca |
|
Nature
2002 Oct 3;419(6906):480-3
ERAAP customizes peptides for MHC class I molecules in
the endoplasmic reticulum.
Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. |
| mERAAP |
cgtagtgatgggacaccat |
|
Nature
2002 Oct 3;419(6906):480-3
ERAAP customizes peptides for MHC class I molecules in
the endoplasmic reticulum.
Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N |
| PKCdelta |
|
gaugaaggaggcgcucagTT |
J
Biol Chem 2002 Oct 10;107(1)
Activation of SAPK/JNK signaling by protein kinase C delta
in response to DNA damage.
Kiyotsugu K, Miki Y, Kufe D. |
| PKCdelta |
|
ggcugaguucuggcuggacTT |
J
Biol Chem 2002 Oct 10;107(1)
Activation of SAPK/JNK signaling by protein kinase C delta
in response to DNA damage.
Kiyotsugu K, Miki Y, Kufe D. |
| EZH2 |
|
|
Nature
2002 Oct 10;419(6907):624-9
The polycomb group protein EZH2 is involved in progression
of prostate cancer.
Varambally S, Dhanasekaran SM, Zhou M, Barrette TR, Kumar-Sinha C, Sanda
MG, Ghosh D, Pienta KJ, Sewalt RG, Otte AP, Rubin MA, Chinnaiyan AM. |
| p8 |
|
ggacguaccaagagagaagCT
cuucucucuugguacguccTT |
EMBO
J 2002 Oct 15;21(20):5427-5436
Signaling pathways and late-onset gene induction associated
with renal mesangial cell hypertrophy.
Goruppi S, Bonventre JV, Kyriakis JM. |
| 53BP1 |
|
gccagguucuagaggaugaTT
ucauccucuagaaccuggcTT |
Science
2002 Oct 3
53BP1, a Mediator of the DNA Damage Checkpoint.
Wang B, Matsuoka S, Carpenter PB, Elledge SJ. |
| 53BP1 |
|
gauacuccuugccugauaaTT
uuaucaggcaaggaguaucTT |
Science
2002 Oct 3
53BP1, a Mediator of the DNA Damage Checkpoint.
Wang B, Matsuoka S, Carpenter PB, Elledge SJ. |
| lacZ |
|
cguacgcggaauacuucgaTT
ucgaaguauuccgcguacgTT |
Science
2002 Oct 3
53BP1, a Mediator of the DNA Damage Checkpoint.
Wang B, Matsuoka S, Carpenter PB, Elledge SJ. |
| GFP |
|
gacccgcgccgaggugaaguu
cuucaccucggcgcgggucuu |
Science
2002 Oct 3
53BP1, a Mediator of the DNA Damage Checkpoint.
Wang B, Matsuoka S, Carpenter PB, Elledge SJ. |
| Btk |
ttggtaaacgatcaaggag |
uugguaaacgaucaaggagTT
cuccuugaucguuuaccaaTT |
FEBS
Lett 2002 Sep 11;527(1-3):274
Silencing of Bruton's tyrosine kinase (Btk) using short
interfering RNA duplexes (siRNA).
Heinonen J, Smith C, Nore B. |
| Btk |
gggaaagaaggaggtttca |
gggaaagaaggagguuucaTT
ugaaaccuccuucuuucccTT |
FEBS
Lett 2002 Sep 11;527(1-3):274
Silencing of Bruton's tyrosine kinase (Btk) using short
interfering RNA duplexes (siRNA).
Heinonen J, Smith C, Nore B. |
| Btk |
gaagcttaaaacctgggag |
gaagcuuaaaaccugggagTT
cucccaccuuuuaagcuucTT |
FEBS
Lett 2002 Sep 11;527(1-3):274
Silencing of Bruton's tyrosine kinase (Btk) using short
interfering RNA duplexes (siRNA).
Heinonen J, Smith C, Nore B. |
| Bmx |
aaagaaggagcatttatgg |
aaagaaggagcauuuauggTT
ccauaaaugcuccuucuuuTT |
FEBS
Lett 2002 Sep 11;527(1-3):274
Silencing of Bruton's tyrosine kinase (Btk) using short
interfering RNA duplexes (siRNA).
Heinonen J, Smith C, Nore B. |
| EGFP |
ggagttgtcccaattcttg |
ggaguugucccaauucuugTT
caagaauugggacaacuccTT |
FEBS
Lett 2002 Sep 11;527(1-3):274
Silencing of Bruton's tyrosine kinase (Btk) using short
interfering RNA duplexes (siRNA).
Heinonen J, Smith C, Nore B. |
| luciferase |
cacttacgctgagtacttcgaaa |
cuuacgcugaguacuucgaTT
ucgaaguacucagcguaagTT |
Nat
Genet 2002 Sep;32(1):107-108
Efficient delivery of siRNA for inhibition of gene expression
in postnatal mice.
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. |
| EGFP |
gcgacgtaaacggccacaagttc |
gacguaaacggccacaaguuc
acuuguggccguuuacgucgc |
Nat
Genet 2002 Sep;32(1):107-108
Efficient delivery of siRNA for inhibition of gene expression
in postnatal mice.
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. |
| SEAP |
caagggcaacttccagaccattg |
agggcaacuuccagaccauTT
auggucuggaaguugcccuTT |
Nat
Genet 2002 Sep;32(1):107-108
Efficient delivery of siRNA for inhibition of gene expression
in postnatal mice.
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. |
| Hepatitis B virus antigen |
aatcactcaccaacctcttgtcc |
ucacucaccaaccucuuguTT
acaagagguuggugagugaTT |
Nat
Genet 2002 Sep;32(1):107-108
Efficient delivery of siRNA for inhibition of gene expression
in postnatal mice.
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. |
| pBluescript |
cggtaagacacgacttatcgcca |
guaagacacgacuuaucgcTT
gcgauaagucgugucuuacTT |
Nat
Genet 2002 Sep;32(1):107-108
Efficient delivery of siRNA for inhibition of gene expression
in postnatal mice.
Lewis DL, Hagstrom JE, Loomis AG, Wolff JA, Herweijer H. |
| luciferase |
cgtacgcggaatacttcga |
cguacgcggaauacuucgaTT
ucgaaguauuccgcguacgTT |
J
Biol Chem 2002 Jul 30
Physical and functional interaction between MCL1 and fortilin.
The potential role of MCL1 as a fortilin chaperone.
Zhang D, Li F, Weidner D, Mnjoyan ZH, Fujise K. |
| laminB1 |
aacgcgcttggtagaggtgga |
|
Oncogene
2002 Jul 18;21(31):4715-27
p53 induces the expression of its antagonist p73 Delta
N, establishing an autoregulatory feedback loop.
Kartasheva NN, Contente A, Lenz-Stoppler C, Roth J, Dobbelstein |
| p73 |
aaccacgagctcgggagggac |
|
Oncogene
2002 Jul 18;21(31):4715-27
p53 induces the expression of its antagonist p73 Delta
N, establishing an autoregulatory feedback loop.
Kartasheva NN, Contente A, Lenz-Stoppler C, Roth J, Dobbelstein |
| GFP |
|
caagcugacccugaaguucuu
gaacuucagggucagcuugug |
Proc
Natl Acad Sci U S A 2002 Aug 21
RNAi functions in cultured mammalian neurons.
Krichevsky AM, Kosik KS. |
| dsRed2 |
|
aguuccaguacggcuccaauu
uuggagccguacuggaacuug |
Proc
Natl Acad Sci U S A 2002 Aug 21
RNAi functions in cultured mammalian neurons.
Krichevsky AM, Kosik KS. |
| MAP2 |
|
cgagaggaaagacgaaggauu
uccuucgucuuuccucucgug |
Proc
Natl Acad Sci U S A 2002 Aug 21
RNAi functions in cultured mammalian neurons.
Krichevsky AM, Kosik KS. |
| YB-1 |
|
cagggcaccuauucagauauu
uaucugaauaggugcccugug |
Proc
Natl Acad Sci U S A 2002 Aug 21
RNAi functions in cultured mammalian neurons.
Krichevsky AM, Kosik KS. |
| ORC6 |
aatggtagccacatccggtgt |
|
Science
2002 Aug 9;297(5583):1026-31
Orc6 involved in DNA replication, chromosome segregation,
and cytokinesis.
Prasanth SG, Prasanth KV, Stillman B
|
| ORC6 |
aagattggacagcaggtcgac |
|
Science
2002 Aug 9;297(5583):1026-31
Orc6 involved in DNA replication, chromosome segregation,
and cytokinesis.
Prasanth SG, Prasanth KV, Stillman B |
| Fortilin |
aaggtaacattgatgactcgc |
gguaacauugaugacucgcTT
gcgagucaucaauguuaccTT |
J
Biol Chem 2002 Jul 30
Physical and functional interaction between MCL1 and fortilin.
The potential role of MCL1 as a fortilin chaperone.
Zhang D, Li F, Weidner D, Mnjoyan ZH, Fujise K. |
| MCL1 |
aataacaccagtacggacggg |
uaacaccaguacggacgggTT
cccguccguacugguguuTT |
J
Biol Chem 2002 Jul 30
Physical and functional interaction between MCL1 and fortilin.
The potential role of MCL1 as a fortilin chaperone.
Zhang D, Li F, Weidner D, Mnjoyan ZH, Fujise K. |
| Luciferase |
|
cuuacgcugaguacuucgaTT
ucgaaguacucagcguaagTT |
Nature
2002 Jul 4;418(6893):38-9
RNA interference in adult mice.
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. |
| NS5B |
|
cugugagaucuacggagccugTT
caggcuccguagaucucacagTT |
Nature
2002 Jul 4;418(6893):38-9
RNA interference in adult mice.
McCaffrey AP, Meuse L, Pham TT, Conklin DS, Hannon GJ, Kay MA. |
| hKIS |
aagcagttcttgccgccagga |
|
EMBO
J 2002 Jul 1;21(13):3390-401
A growth factor-dependent nuclear kinase phosphorylates
p27(Kip1) and regulates cell cycle progression.
Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel
EG. |
| mKIS |
aagcagttcctgcctcgggga |
|
EMBO
J 2002 Jul 1;21(13):3390-401
A growth factor-dependent nuclear kinase phosphorylates
p27(Kip1) and regulates cell cycle progression.
Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel
EG. |
| hPlk1 |
aagggcggctttgccaagtgctt |
|
Proc
Natl Acad Sci U S A 2002 Jun 25;99(13):8672-6
Activation of Cdc2/cyclin B and inhibition of centrosome
amplification in cells depleted of Plk1 by siRNA.
Liu X, Erikson RL. |
| CD4 |
|
gaucaagagacuccucaguGA
acugaggagucucuugaucTG |
Nat
Med 2002 Jul;8(7):681-6
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman
RG, Lieberman J, Shankar P, Sharp PA. |
| p24 |
|
gauuguacugagagacaggcu
ccugucucucaguacaaucuu |
Nat
Med 2002 Jul;8(7):681-6
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman
RG, Lieberman J, Shankar P, Sharp PA. |
| GFP |
|
ggcuacguccaggagcgcacc
ugcgcuccuggacguagccuu |
Nat
Med 2002 Jul;8(7):681-6
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman
RG, Lieberman J, Shankar P, Sharp PA. |
| HPRT |
|
gugucauuagugaaacuggaa
ccaguuucacuaaugacacaa |
Nat
Med 2002 Jul;8(7):681-6
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman
RG, Lieberman J, Shankar P, Sharp PA. |
| CD19 |
|
uaguaggaggcaggccccaga
gaaucauccuccguccggggu |
Nat
Med 2002 Jul;8(7):681-6
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman
RG, Lieberman J, Shankar P, Sharp PA. |
| hRad9 |
aagtctttcctgtctgtcttc |
|
J
Biol Chem 2002 Jul 12;277(28):25722-7
A role of the C-terminal region of human Rad9 (hRad9) in
nuclear transport of the hRad9 checkpoint complex.
Hirai I, Wang HG. |
| GFP |
aagacccgcgccgaggtgaag |
|
J
Biol Chem 2002 Jul 12;277(28):25722-7
A role of the C-terminal region of human Rad9 (hRad9) in
nuclear transport of the hRad9 checkpoint complex.
Hirai I, Wang HG. |
| MBD2 |
aagaggattgcccggcc |
|
J
Biol Chem 2002 Jun 21;277(25):22573-80
Methyl-CpG binding domain protein 2 represses transcription
from hypermethylated pi-class glutathione S-transferase gene promoters in
hepatocellular carcinoma cells.
Bakker J, Lin X, Nelson WG. |
| MeCP2 |
aagcatgagcccgtgcagcca |
|
J
Biol Chem 2002 Jun 21;277(25):22573-80
Methyl-CpG binding domain protein 2 represses transcription
from hypermethylated pi-class glutathione S-transferase gene promoters in
hepatocellular carcinoma cells.
Bakker J, Lin X, Nelson WG. |
| lamin A |
aaggacctggaggctctgctg |
|
J
Biol Chem 2002 Jun 21;277(25):22573-80
Methyl-CpG binding domain protein 2 represses transcription
from hypermethylated pi-class glutathione S-transferase gene promoters in
hepatocellular carcinoma cells.
Bakker J, Lin X, Nelson WG. |
| hMps1 |
|
|
EMBO
J 2002 Apr 2;21(7):1723-32
Human Mps1 kinase is required for the spindle assembly
checkpoint but not for centrosome duplication.
Stucke VM, Sillje HH, Arnaud L, Nigg EA. |
| h/m-shc |
|
cuacuugguucgguacauggg
cauguaccgaaccaaguagga |
Biochem
J 2002 Apr 1;363(Pt 1):1-5
Isoform-specific knockdown and expression of adaptor protein
ShcA using small interfering RNA.
Kisielow M, Kleiner S, Nagasawa M, Faisal A, Nagamine Y. |
| p66-shc |
|
gaaugagucucugucaucguc
cgaugacagagacucauuccg |
Biochem
J 2002 Apr 1;363(Pt 1):1-5
Isoform-specific knockdown and expression of adaptor protein
ShcA using small interfering RNA.
Kisielow M, Kleiner S, Nagasawa M, Faisal A, Nagamine Y. |
| Cdc14A |
gcacagtaaatacccactatt |
|
Nat
Cell Biol 2002 Apr;4(4):318-22
Deregulated human Cdc14A phosphatase disrupts centrosome
separation and chromosome segregation.
Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J. |
| NuMA |
NM_006185 |
AGCAACAGTGCCAGAGCTGCAGA-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| GAS41 |
NM_006530 |
AAGAAAAGAGAAGAAGATGGGCA-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| SV40 T-antigen |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| laminA/C |
NM_005572 |
TCGGCTGAAGGACCTGGAGGCTC-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| lamin B1 |
NM_005573 |
AAGCTGCAGATCGAGCTGGGCAA-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| lamin B2 |
M94362 |
AAGAGGAGGAGGAAGCCGAGTTT-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| LAP2 |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| emerin |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| Nup153 |
NM_005124 |
AGTGTTCAGTATGCTGTGTTTCT-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| beta-actin |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| beta-actin |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| ARC21 |
AF006086 |
TGTCTTCTTCAAAAACTATGAAA-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| mouse zyxin |
X99063 |
TCAGAGGCAGAGCGTGGCAGTGA-dTdT |
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| mouse vinculin |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| VASP |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| vimentin |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| keratin18 |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| Eg5 |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| CENP-E |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| cytoplasmic dynein 1 heavy chain |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| cdk1 |
|
|
J
Cell Sci 2001 Dec;114(Pt 24):4557-65
Identification of essential genes in cultured mammalian
cells using small interfering RNAs.
Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. |
| SK-1 |
|
gagcugcaaggccuugcccTT
gggcaaggccuugcagcucTT |
J
Biol Chem 2002 Feb 22;277(8):6667-75
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine
1-phosphate generation and the induction of angiogenic vascular maturation.
Ancellin N, Colmont C, Su J, Li Q, Mittereder N, Chae SS, Stefansson
S, Liau G, Hla T. |
| GL-2, GL-3 luciferase |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
| pRL-TK |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
| lamin A/C |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
| laminB1 |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
| NyMA |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
| vimentin |
|
|
Nature
2001 May 24;411(6836):494-8
Duplexes of 21-nucleotide RNAs mediate RNA interference
in cultured mammalian cells.
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. |
|
|
|
|