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Insulin Aspart (rDNA Origin) Injection

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Why is this medication prescribed?   Return to top

Insulin aspart is used to treat type 1 (insulin-dependent) diabetes (formerly called 'juvenile-onset'). It is also used to treat people with type 2 (noninsulin-dependent) diabetes (formerly called 'adult-onset') who need insulin to control their diabetes. Insulin aspart is a short-acting, man-made version of human insulin. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.

How should this medicine be used?   Return to top

Insulin aspart comes as a solution (liquid) to inject subcutaneously (under the skin). It is usually injected immediately before meals (5-10 minutes before eating). Insulin aspart can also be infused under the skin using an external insulin pump. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use insulin aspart injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Because insulin aspart is a short-acting insulin, it may be used as an injection in combination with some other longer-acting insulins. If insulin aspart is mixed with NPH human insulin, insulin aspart should be drawn into the syringe first, and the solution should be injected immediately after mixing. When insulin aspart is used in an insulin pump, it should not be diluted or mixed with any other insulin or solution.

Insulin aspart controls diabetes but does not cure it. Continue to use insulin aspart even if you feel well. Do not stop using insulin aspart without talking to your doctor. Do not switch to another brand or type of insulin or change the dose of any type of insulin you are using without talking to your doctor.

Insulin aspart comes in vials, cartridges that contain medication and are to be placed in dosing pens, and dosing pens that contain cartridges of medication. Be sure you know what type of container your insulin aspart comes in and what other supplies, such as needles, syringes, or pens, you will need to inject your medication.

If your insulin aspart comes in vials, you will need to use syringes to inject your dose. Ask your doctor or pharmacist if you have questions about the type of syringe you should use.

If your insulin aspart comes in cartridges, you will need to buy an insulin pen separately. Check the manufacturer's information for the patient to see what type of pen is right for the cartridge size you are using. Carefully read the instructions that come with your pen, and ask your doctor or pharmacist to show you how to use it. Ask your doctor or pharmacist if you have questions about the type of pen you should use.

If your insulin aspart comes in pens, be sure to read and understand the manufacturer's instructions. Ask your doctor or pharmacist to show you how to use the pen. Follow the directions carefully. Never remove the cartridge from the pen or attempt to add any other type of insulin to the cartridge.

Never reuse needles or syringes and never share needles, syringes, cartridges, or pens. If you are using an insulin pen, always remove the needle right after you inject your dose. Throw away needles and syringes in a puncture-resistant container. Ask your doctor or pharmacist how to dispose of the puncture resistant container.

Always look at your insulin aspart before you inject it. It should be as clear, colorless, and fluid as water. Do not use your insulin aspart if it is colored, cloudy, thickened, or contains solid particles, or if the expiration date on the bottle has passed.

If your insulin aspart comes in vials, follow these steps to prepare your dose:

To inject a prepared dose of insulin aspart using a syringe or pen, follow these steps:

Use a different site for each injection, about 1 inch away from the previous injection but in the same general area (for example, the thigh). Use all available sites in the same general area before switching to a different area (for example, the upper arm). Do not use the same injection site more often than once every month.

If you use insulin aspart in an insulin pump, change the tubing and needle and throw away any solution left in the reservoir at least every 48 hours. You should also change the injection site at least every 48 hours.

Other uses for this medicine   Return to top

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?   Return to top

Before using insulin aspart injection,

What special dietary instructions should I follow?   Return to top

Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. It is important to eat a healthy diet.

Alcohol may cause a decrease in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are using insulin aspart.

What should I do if I forget a dose?   Return to top

Insulin aspart must be injected shortly before or after a meal. If you remember your dose before or shortly after your meal, inject the missed dose right away. If some time has passed since your meal, call your doctor to find out whether you should inject the missed dose. Do not inject a double dose to make up for a missed one.

What side effects can this medication cause?   Return to top

This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.

You may experience hypoglycemia (low blood sugar) while you are taking this medication. Your doctor will tell you what you should do if you develop hypoglycemia. He or she may tell you to check your blood sugar, eat or drink a food or beverage that contains sugar, such as hard candy or fruit juice, or get medical care. Follow these directions carefully if you have any of the following symptoms of hypoglycemia:

If hypoglycemia is not treated, severe symptoms may develop. Be sure that your family, friends, and other people who spend time with you know that if you have any of the following symptoms, they should get medical treatment for you immediately.

Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar) :

If high blood sugar is not treated, a serious, life-threatening condition called diabetic ketoacidosis could develop. Call your doctor immediately if you have any of the these symptoms:

Insulin aspart injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

Insulin aspart may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?   Return to top

Store unopened insulin aspart vials, cartridges, and pens in the refrigerator. Do not freeze. Unopened refrigerated insulin aspart can be stored until the date shown on the company's label.

If no refrigerator is available (for example, when on vacation), store the vials or cartridges at room temperature and away from direct sunlight and extreme heat. Unrefrigerated vials, cartridges, and pens can be used within 28 days or they must be thrown away. Opened vials can be stored for 28 days at room temperature or in the refrigerator. Opened cartridges and pens may be stored at room temperature for up to 28 days; do not refrigerate them. Throw away any insulin aspart that has been exposed to extreme heat or cold.

When traveling, protect your insulin aspart vials, cartridges, and pens from bumps or other rough handling (wrap them in clothes in the middle of a suitcase). Do not keep insulin in hot areas of a car such as the glove compartment or trunk. When traveling by airplane, do not put insulin in checked luggage since the luggage may be lost. Always keep insulin with you or in carry-on luggage.

Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose   Return to top

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include the symptoms of hypoglycemia listed above and the following:

What other information should I know?   Return to top

Keep all appointments with your doctor and the laboratory. Your blood sugar and glycosylated hemoglobin (HbA1c) should be checked regularly to determine your response to insulin aspart.

To monitor the effectiveness of insulin aspart, measure the amount of sugar (glucose) in your blood or urine (when blood sugar is above a certain high level, you will have sugar in your urine). For measuring the amount of glucose in your blood, you can use a blood glucose meter. For the urine measurements, you will need special paper tapes, tablets, or plastic strips that change color depending on how much sugar is present. Your doctor also may ask you to test your urine for ketones (substances present when diabetes is not under control). Follow your doctor's directions for testing your urine and blood and for recording the results. If your blood sugar is high or if sugar or ketones are present in your urine, call your doctor.

Your dose of insulin aspart may need to be changed when you are ill (especially with fever, vomiting, or diarrhea), have emotional changes or stress, gain or lose weight, or change the amount of food you eat or amount of exercise you do. If any of these things happen, call your doctor.

See your dentist twice yearly; see your eye doctor regularly; get your blood pressure checked regularly.

If you travel across time zones, ask your doctor how to time your injections. When you travel, take extra insulin and supplies with you.

Keep yourself and your clothes clean. Wash cuts, scrapes, and other wounds quickly, and do not let them get infected. Wear medical alert identification (a bracelet or tag) that says you have diabetes.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names   Return to top

  • NovoLog®

Last Revised - 08/01/2006

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The MedMaster™ Patient Drug Information database provides information copyrighted by the American Society of Health-System Pharmacists, Inc., Bethesda, Maryland Copyright© 2007. All Rights Reserved.