A man has been charged with murder after a bar brawl in which another man was killed in Sydney's south-west.

The 43-year-old Lansvale man is due to appear at Liverpool Local Court this morning.

A 34-year-old man died in hospital today from critical head injuries he suffered during the brawl last night at a registered club on Fairview Road at Cabramatta.

Police said the man's family had his life support turned off at Liverpool Hospital about 6am (AEST) today.

A fight broke out between a number of patrons at the club around  9pm last night, police said.

During the fight, the man struck his head on a bar stool as he fell to the ground.

Police are continuing their inquiries.

AAP