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siRNA and RNAi resource
Introduction to miRNAs

Definition and Overview

miRNA Processing

miRNA Function

Expression & Targets

Exploration: Introduction to microRNAs

Workflow: miRNA Expression Analysis

Ambion Resources

miRNA Database
Find information and products

miRNA Array Resource

miRNA Research Guide (PDF)
[Request a hardcopy]

New Ambion Articles

Tips from the Bench: The Optimal Thickness of FFPE Sections for miRNA Isolation

Gene Expression Profiling and miRNA Discovery in a Carcinoma Model

Tips from the Bench: Stability of miRNA at Sub-Zero Temperatures

Simple, Rapid, Quantitative, and Sensitive Tools for miRNA Profiling

Research Highlight: Identification of Tropomyosin 1 as a Downstream Target of mir-21

[more...]

Ambion Products

All miRNA Products

Product Citations

NEW Product!
TaqMan® MicroRNA Cells-to-CT™ Kit
The TaqMan MicroRNA Cells-to-CT Kit makes it possible to perform microRNA (miRNA) expression profiling directly from cultured cells without RNA purification. The kit is the first to offer a simple, complete workflow for miRNA expression analysis from a few samples, or it can easily be incorporated into automated, high throughput applications.

Ambion Publications

Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ. The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells. Cancer Res. 2007 Aug 15;67(16):7713-22. [Abstract]

Shingara J, Keiger K, Shelton J, Laosinchai-Wolf W, Powers P, Conrad R, Brown D, Labourier E. An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA. 2005 Jul 25; [Epub ahead of print] [Abstract]

Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ. RAS is regulated by the let-7 microRNA family. Cell. 2005 Mar 11;120(5):635-47. [Abstract]

Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 2005 Mar 1;33(4):1290-7. [Abstract]

Ambion Webinar
microRNAs: Applying the Latest microRNA Analytical Tools to Study the Involvement of microRNAs in Human Cancer

Presented live on
July 20, 2006

[View]

External Web Resources

Bio.com InFocus Webcast: "miRNAs in Stem Cell Development"
Broadcast October 26, 2006

miRBase: The Home of microRNA Data

A Uniform System for microRNA Annotation


miRNA in the News

Expression Patterns of MicroRNAs Appear Altered in Colon Cancer, and Associated with Poor Outcomes - 1/30/08

2 MicroRNAs Promote Spread of Tumor Cells - 1/28/08

MIT Reports New Twist in MicroRNA Biology - 1/13/08

Small RNAs Can Prevent Spread of Breast Cancer - 1/9/08

MicroRNA Regulates Cancer Stem Cells - 12/13/07

Silencing Small But Mighty Cancer Inhibitors - 12/10/07

Scientists Discover New Role for miRNA in Leukemia - 12/9/07

Massive MicroRNA Scan Uncovers Leads to Treating Muscle Degeneration - 10/17/07

MicroRNAs May Be Key to HIV's Ability to Hide, Evade Drugs, Jefferson Scientists Find - 9/30/07

Tiny RNAs, Big Problems - 9/26/07

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