Submissions tagged with interactome
(4 documents)
Disordered proteins and network disorder in network descriptions of protein structure, dynamics and function. Hypotheses and a comprehensive review
During the last decade, network approaches became a powerful tool to describe protein structure and dynamics. Here we review the links between disordered proteins and the associated networks, and d…
Received 31 January 2011 14:29 UTC; Posted 31 January 2011
Posted to: Bioinformatics
Charting the NF-kB pathway interactome map
One of the phenomena observed in human aging is the progressive increase of a systemic inflammatory state, a condition referred to as “inflammaging”, negatively correlated with longevity. The five …
Received 16 November 2010 15:15 UTC; Posted 16 November 2010
Posted to: Genetics & Genomics, Immunology, Bioinformatics
Evolutionary descent of prion genes from a ZIP metal ion transport ancestor
In the more than 20 years since its discovery, both the phylogenetic origin and cellular function of the prion protein (PrP) have remained enigmatic. Insights into the function of PrP may be obtain…
Received 10 February 2009 21:16 UTC; Posted 10 February 2009
Posted to: Genetics & Genomics, Molecular Cell Biology, Evolutionary Biology
M. tuberculosis interactome analysis unravels potential pathways to drug resistance
Drug resistance is a major problem for combating tuberculosis. Lack of understanding of how resistance emerges in bacteria upon drug treatment limits our ability to counter resistance. By analysis …
Received 11 March 2008 04:34 UTC; Posted 11 March 2008
Posted to: Microbiology, Bioinformatics
