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siRNA and RNAi resource
Introduction to miRNAs

Definition and Overview

miRNA Processing

miRNA Function

Expression & Targets

Exploration: Introduction to microRNAs

Workflow: miRNA Expression Analysis

Ambion Resources

miRNA Database
Find information and products

miRNA Array Resource

miRNA Research Guide (PDF)
[Request a hardcopy]

New Ambion Articles

Tips from the Bench: The Optimal Thickness of FFPE Sections for miRNA Isolation

Gene Expression Profiling and miRNA Discovery in a Carcinoma Model

Tips from the Bench: Stability of miRNA at Sub-Zero Temperatures

Simple, Rapid, Quantitative, and Sensitive Tools for miRNA Profiling

Research Highlight: Identification of Tropomyosin 1 as a Downstream Target of mir-21

[more...]

Ambion Products

All miRNA Products

Product Citations

NEW Product!
TaqMan® MicroRNA Cells-to-CT™ Kit
The TaqMan MicroRNA Cells-to-CT Kit makes it possible to perform microRNA (miRNA) expression profiling directly from cultured cells without RNA purification. The kit is the first to offer a simple, complete workflow for miRNA expression analysis from a few samples, or it can easily be incorporated into automated, high throughput applications.

Ambion Publications

Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ. The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells. Cancer Res. 2007 Aug 15;67(16):7713-22. [Abstract]

Shingara J, Keiger K, Shelton J, Laosinchai-Wolf W, Powers P, Conrad R, Brown D, Labourier E. An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA. 2005 Jul 25; [Epub ahead of print] [Abstract]

Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ. RAS is regulated by the let-7 microRNA family. Cell. 2005 Mar 11;120(5):635-47. [Abstract]

Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 2005 Mar 1;33(4):1290-7. [Abstract]

Ambion Webinar
microRNAs: Applying the Latest microRNA Analytical Tools to Study the Involvement of microRNAs in Human Cancer

Presented live on
July 20, 2006

[View]

External Web Resources

Bio.com InFocus Webcast: "miRNAs in Stem Cell Development"
Broadcast October 26, 2006

miRBase: The Home of microRNA Data

A Uniform System for microRNA Annotation


miRNA in the News

MicroRNAs, EMT and Cancer Progression - 3/31/08

Replacing Absent MicroRNAs Could Make Tumors Less Invasive, More Treatable - 3/31/08

MicroRNAs Make Big Impression in Disease After Disease - 3/28/08

Accurate Identification of Tumor Origin Using MicroRNAs is Published by Rosetta Genomics' Scientists and Collaborators in Nature Biotechnology - 3/25/08

Yale Scientists Show That A microRNA Can Reduce Lung Cancer Growth - 3/20/08

MicroRNAs Help Zebrafish Regenerate Fins - 3/16/08

Low Micro-RNA Level Linked to High Gene Activity in AML - 3/6/08

Gladstone Scientists Identify Role of Tiny RNAs in Controlling Stem Cell Fate - 3/5/08

Short RNA Strand Helps Exposed Skin Cells Protect Body from Bacteria, Dehydration and Even Cancer - 3/2/08

 
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