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Toxicological Profile

Toxicological Profile

August 1995

Dinitrophenols Toxicological Profile PDF PDF Version, 5.9 MB

CAS#: 2,4-Dinitrophenol 51-28-5

Toxicological Profile Information

The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. The complete list of topics covered (chapter titles) is shown at the left and in more detail further down this page.

The focus of the profile is on health and toxicologic information. Therefore, each profile begins with a Public Health Statement that summarizes in nontechnical language, a substance's relevant properties.

A useful two page information sheet, the ToxFAQs, is also available.

Toxicological Profile Access

In order to access the ATSDR toxicological profiles' PDF files below, you must have Adobe Acrobat Reader .

You may download that program for free from this link to Adobe Exiting the ATSDR Web Site. and then use it to access (open) the files below that are labeled as PDF files.

Toxicological Profile PDF Complete Profile, 5.9 MB

The table of contents and list of individual PDF files are given below.

Preface PDF Preface, 489 KB

Public Health Statement PDF 1. Public Health Statement, 142 KB

1.1 What is this substance?
1.2 What happens to it when it enters the environment?
1.3 How might I be exposed to it?
1.4 How can it enter and leave my body?
1.5 How can it affect my health?
1.6 Is there a medical test to determine whether I have
been exposed to it?
1.7 What recommendations has the federal government
made to protect human health?
1.8 Where can I get more information?

Relevance to Public Health PDF 2. Health Effects, 3.6 MB

2.1 Introduction
2.2 Discussion of health effects by route of exposure
2.3 Toxicokinetics
2.4 Mechanisms of action
2.5 Relevance to public health
2.6 Biomarkers of exposure and effect
2.7 Interactions with other substances
2.8 Populations that are unusually susceptible
2.9 Methods for reducing toxic effects
2.10 Adequacy of the database

Health Effects PDF 3. Chemical and Physical Information, 378 KB

3.1 Chemical Identity
3.2 Physical and Chemical Properties

Chemical and Physical Information PDF 4. Production, Import, Use, and Disposal, 224 KB

4.1 Production
4.2 Import / Export
4.3 Use
4.4 Disposal

Production, Import, Use, and Disposal PDF 5. Potential for Human Exposure, 510 KB

5.1 Overview
5.2 Releases to the environment
5.3 Environmental fate
5.4 Levels monitored or estimated in the environment
5.5 General population and occupational exposure
5.6 Populations with potentially high exposure
5.7 Adequacy of the database

Potential for Human Exposure PDF 6. Analytical Methods, 336 KB

6.1 Biological materials
6.2 Environmental samples
6.3 Adequacy of the database

Analytical Methods PDF 7. Regulations and Advisories, 429 KB

Regulations and Advisories PDF 8. References, 194 KB

References PDF 9. Glossary, 166 KB

Appendices PDF Appendices, 358 KB

A. Minimal risk level worksheets
B. User's guide
C. Acronyms, abbreviations, and symbols


Agency for Toxic Substances and Disease Registry (ATSDR). 1995. Toxicological profile for Dinitrophenols. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service.


All ATSDR toxicological profile PDF files are electronic conversions from paper copy or other electronic ASCII text files. This conversion may have resulted in character translation or format errors. Users are referred to the original paper copy of the toxicological profile for the official text, figures, and tables. Original paper copies can be obtained via the directions on the toxicological profile home page, which also contains other important information about the profiles.

Where can I get more information?

ATSDR can tell you where to find occupational and environmental health clinics. Their specialists can recognize, evaluate, and treat illnesses resulting from exposure to hazardous substances. You can also contact your community or state health or environmental quality department if you have any more questions or concerns.

For more information, contact:
Agency for Toxic Substances and Disease Registry
Division of Toxicology and Environmental Medicine
1600 Clifton Road NE, Mailstop F-32
Atlanta, GA 30333
Phone: 1-800-CDC-INFO • 888-232-6348 (TTY) 
This page was updated on 10/01/2007