The designs on the various denominations of Clydesdale Bank notes portray eminent Scots and items connected to them, as follows:-
Robert Burns, the poet with a field mouse and wild rose prompted by two of his famous poems.
Mary Slessor, the missionary to West Africa. There is an illustration of Slessor's work in Calabar (Nigeria) including a map of the area and a lithographic vignette depicting her work with children.
In 2006 the bank issued a commemorative £10 note to mark its sponsorship of the Scottish Commonwealth Games team. The note displays the team logo on the front, while the rear shows a montage of all the events at the games.
Robert the Bruce, a Scottish warrior and King, who successfully fought to free Scotland from the English monarch. On the rear of this note is a representation of the statue to Robert the Bruce at Bannockburn (the location of a defeat of the army of King Edward I of England in 1314), the Monymusk reliquary, Stirling Castle and the monument to William Wallace. The Bank also issued a new style £20 in Dec 2005. The front of the note has been updated with the Bank’s new logo while the rear combines an image of the Bank’s new Exchange building with some artwork from the Head Office building
In 1999, to mark Glasgow's celebrations as UK City of Architecture and Design, Clydesdale Bank issued a £20 with a portrait of Alexander "Greek" Thomson, one of the city's famous architects. On the rear of the note is a drawing of the "Lighthouse" building designed by another Glasgow architect, Charles Rennie Mackintosh, plus a representation of the dome in Holmwood House, another example of "Greek" Thomson's work.
In 2006 the Bank issued a commemorative £20 to mark the 700th anniversary of Robert the Bruce’s coronation. The front of the new note displays the Coat of Arms used by Robert the Bruce on his personal seal. The rear displays a narrative commemorating the anniversary.
Adam Smith the economist and author of "The Wealth of Nations". On the reverse is a montage of eighteenth century engineering and agricultural machinery with Kirkcaldy Harbour in the background.
Lord Kelvin the researcher and inventor. He is shown with the improved mariner's compass which he invented and a map with the route of the first commercially successful transatlantic cable. Lord Kelvin was the engineer in charge of the project. On the reverse of the note is his university lecture room.