Neurobiology

Programs Offered

• Program in Neuroscience
• Affiliated Graduate Programs

Program in Neuroscience

The Department faculty are committed to training leaders of the next generation of neuroscientists. Candidates for the Ph.D. in Neurobiology are admitted to the graduate Program in Neuroscience. This interdepartmental training program links the Department of Neurobiology with faculty in the Harvard affiliated hospitals and with faculty in other basic science departments. The Program, established in 1981, now includes about 90 investigators who participate in the training of Ph.D. candidates. Approximately fifteen students are accepted each year so that the steady state enrollment is usually about 80-90. This Program in Neuroscience attracts superb students with a broad range of interests from all areas of the globe.

The goals of our training are to produce scientists who have explored one area and one level of analysis in great depth, but who are familiar with the full scope of neuroscience. They should be able to move from one level to another in a critical and creative manner. We also try to develop an appreciation for translational research that bears on human brain disease.

During the first one and a half to two years, Ph.D. students select from a series of graduate level courses. Current offerings include:

• Introduction to Neurobiology
  Spans modern neuroscience from molecular neurobiology to perception and cognition.
• Cellular Neurophysiology
  Introduction to the physiology of neurons and muscle cells.
• Molecular Neurobiology
  Introduction to the molecular biology and genetics of the nervous system.
• Developmental Neurobiology
  Development of the nervous system.
  Neuro Course 207
• Neurobiology of Disease
  Patient presentations and core lectures describing clinical aspects of a disease or disorder, the pathology, and the basic science information needed to help in understanding the diseases or disorder.
• Central Nervous System Neurophysiology
  Introduction to the physiology of circuits in the vertebrate central nervous system.
• Advanced Topics in Neuroscience
  A series of reading and discussion seminars on selected topics in neuroscience.

In addition to the seminars offered within the Department of Neurobiology, students expand their horizons by taking courses in subjects that are not closely related to their area of specialization. In the recent past, our students have selected courses in biochemistry, immunology, genetics, applied mathematics, electronics, embryology, or computer science offered at Harvard College, MIT, or in any of the other graduate programs at the medical school.

Laboratory rotations of at least three months duration are designed to provide hands-on experience in diverse techniques and approaches. Students are expected to complete two rotations. These experiences often serve as the basis for selecting a thesis advisor.

Selected recent Ph.D. theses that illustrate the diversity of research in the Department of Neurobiology:

• Doris Tsao
  Margaret Livingstone, Advisor
  Stereopsis
• Jonathan Trinidad
  Jonathan Cohen, Advisor
  The Localization and Function of Neuregulin and the ErbB Receptors at the Neuromuscular Junction
• Hien Tran
  Michael Greenberg, Advisor
  A Role for Forkheads in the Response to Stress
• Fu-Chia Yang
  Charles Weitz, Advisor
  The Potential Role for the EGF Receptor System in the Circadian Regulation of Locomotor Activity
• Bruce Altevogt
  David Paul, Advisor
  Analysis of Connexinx in Myelination
• Heather Heerssen
  Rosalind Segal, Advisor
  Mechanisms of Trk Receptor Retrograde Transport and Signaling
• Sarah Webster
  Gary Yellen, Advisor
  Structures and Mechanisms of Gating in Shaker Voltage-Dependent Potassium Channels
• Michael Do
  Bruce Bean, Advisor
  Generation and Regulation of Pacemaking in Subthalamic Neuron

The Program in Neuroscience is one of four programs administered by the Division of Medical Sciences (DMS). DMS, located at the medical school, is a division of the Faculty of Arts and Sciences of Harvard University.

For further information about applications and life within the Program, contact:

Karen Harmin ,
Administrator
Program in Neuroscience,
Department of Neurobiology,
Harvard Medical School, 220 Longwood Avenue, Boston, MA 02115
Phone: (617) 432-0912
Email: neurosciPhD@hms.harvard.edu

Neuroscience Web Site
Applications to the Program can also be obtained from:
Division of Medical Sciences
Harvard Medical School
260 Longwood Avenue
Boston, MA 02115

Phone: (617) 432-0162
Email: dms@hms.harvard.edu