Please keep wiki links as wiki links, use external links only if there is no existing page for the IDE.

Reviews

Python Development Environments (IDEs) part1, part2 (Ian Ozsvald, 2007-05-14)
ShowMeDo Blog: Choosing a Python IDE (Jeremy Jones, 2007-03-08)
September 2005 Review of 6 Python IDEs (PyDev, Eric3, Boa, BlackAdder, Komodo, Wing) and the February 2006 follow-up review of 4 (PyDev, SPE, Komodo, Wing)
Charming Python: Review of Python IDEs (David Mertz, 2003-12-11)
Charming Python: A review of Python IDEs (David Mertz, 2001-05-01)
A New Harvest of Python IDEs (Boudewijn Rempt, 2000-11-27)

and these ShowMeDo videos for Wing 3 Professional SPE, PyDev (inside Eclipse) and IPython.

IDEs with introspection-based code completion and integrated debugger

Name	Platform	Updated	Notes
Komodo	Windows/Linux/Mac OS X	2008	Multi-language IDE. Available as Komodo IDE (commercial) and Komodo Edit (open source, as part of the OpenKomodo project)
NetBeans	Linux, Mac, Solaris, Windows	2009	Python/Jython support in NetBeans -- Allows Python and Jython Editing, code-completion, debugger, refactoring, templates, syntax analysis, etc.; see also http://wiki.netbeans.org/Python
PyDev	Eclipse	2008	Open source plugin for Eclipse -- Allows Python and Jython Editing, code-completion, debugger, refactoring, templates, syntax analysis, etc.; see also PyDev Extensions
WingIde	Windows/Linux/Mac OS X/Unix	2008	Commercial with networked debugger, integrated unit testing, source browser, and syntax coloring/auto-completing editor. Free of charge license for non-commercial open-source developers with an established project.

Name	Platform	Updated	Notes
BlackAdder	Windows/Linux	2004	Commercial; integrated debugger; interfaces with Qt Designer
eric	Python + PyQt + QScintilla	2008	Open Source ,interfaces with Qt Designer, Qt Linguist, unittest; integrated debugger
PIDA	Python + GTK	2007	Integrated source control, debugger, and profiler
PyScripter	Windows	2008	Integrated debugger. Requires Python 2.3 or later to be installed
SPE	Windows, Linux, MacOsX, FreeBSD, more	2008	Open-source with wxPython interface. Code completion, call tips, class explorer, source index, auto todo list, Blender support, integrated PyChecker (source code doctor) and Kiki (regex console). Download instructions
Pida	Linux, FreeBSD, ..., (Windows in progress)	2007 (2008 dev)	Open-source with GTK interface, written in Python. Supports different languages, python trough rope and pyflakes as well as rpdb2. Support different Editors (Vim, Medit, Emacs) Current Repos

Name	Platform	Updated	Notes
BoaConstructor	Python + wxPython	2007	RAD GUI building IDE for wxPython, similar to Delphi.
PythonCard	Python + wxPython	2006	RAD GUI building IDE
Xcode	Mac OS X 10.5 and later	2008	Apple's free of charge IDE now with full Python GUI making. Requires free developer registration for download.

Take a look at PythonEditors if you prefer something lightweight. IDEs that don't integrate anything Python-specific are also listed here.