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Mr Vaile said he still expected protests, but had been assured by police that the new site was more easily secured.
He stressed that the meeting, to be held from November 14-15, would be small and informal, with no decision-making role and with an agenda devoted substantially to trade problems facing the poorest nations.
The meeting must find solutions to several problems for which a deadline of December31 was set at the last round of negotiations.
Among them is the humanitarian problem of access to medicines by the poorest countries.
It already has been agreed that, under some circumstances, drug companies may be forced to license pharmaceutical patents to other manufacturers, if they themselves have no manufacturing base in the country concerned. However, a means has yet to be agreed to get vital drugs to those countries that have no pharmaceutical manufacturing capacity.
The Sydney meeting will also consider "special and differential treatment" of developing countries.
"Seventeen of the 25 countries attending are developing countries. Their presence will ensure this meeting can give close attention to their interests," Mr Vaile said.
He said that representatives of "a number" of non-government organisations concerned about the impacts of globalisation would be "invited to share their views with ministers".
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