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hypogammaglobulinemia (hi″po-gam″ә-glob″u-lĭ-neĀ“me-ә)   abnormally low levels of all classes of immunoglobulins, associated with heightened susceptibility to infectious diseases; see also agammaglobulinemia, dysglobulinemia, and immunodeficiency.

common variable hypogammaglobulinemia  common variable immunodeficiency.

physiologic hypogammaglobulinemia  a normal period of hypogammaglobulinemia seen in all infants at about 5–6 months of age as the level of transplacentally acquired maternal immunoglobulins declines before endogenous immunoglobulin synthesis rises to normal levels.

transient hypogammaglobulinemia of infancy  prolongation of the normal physiologic hypogammaglobulinemia of infancy caused by delayed development of endogenous immunoglobulin production and associated with increased susceptibility to infections.

X-linked hypogammaglobulinemia  X-linked agammaglobulinemia.

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