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Mobile Site You Are Here > Home > Leaders & Records > Single-Season Strikeouts
Single-Season Leaders & Records for Strikeouts
+ - Indicates Hall of Famer. Bold indicates active player.
Only players who finished in the top 40 for the majors in a season will appear on this list.
Leaders from the current season are only included for rate stats after July 1st.
| Rank | Player (age that year) | Strikeouts | Year | Bats |
|---|---|---|---|---|
| 1. | Mark Reynolds (25) | 223 | 2009 | R |
| 2. | Mark Reynolds (26) | 211 | 2010 | R |
| 3. | Mark Reynolds (24) | 204 | 2008 | R |
| 4. | Adam Dunn (30) | 199 | 2010 | L |
| Ryan Howard (27) | 199 | 2007 | L | |
| Ryan Howard (28) | 199 | 2008 | L | |
| 7. | Jack Cust (29) | 197 | 2008 | L |
| 8. | Adam Dunn (24) | 195 | 2004 | L |
| 9. | Adam Dunn (26) | 194 | 2006 | L |
| 10. | Bobby Bonds (24) | 189 | 1970 | R |
| 11. | Jose Hernandez (32) | 188 | 2002 | R |
| 12. | Bobby Bonds (23) | 187 | 1969 | R |
| Preston Wilson (25) | 187 | 2000 | R | |
| 14. | Rob Deer (26) | 186 | 1987 | R |
| Ryan Howard (29) | 186 | 2009 | L | |
| 16. | Jack Cust (30) | 185 | 2009 | L |
| Jose Hernandez (31) | 185 | 2001 | R | |
| Pete Incaviglia (22) | 185 | 1986 | R | |
| Jim Thome (30) | 185 | 2001 | L | |
| 20. | Rickie Weeks (27) | 184 | 2010 | R |
| 21. | Cecil Fielder (26) | 182 | 1990 | R |
| Jim Thome (32) | 182 | 2003 | L | |
| 23. | Ryan Howard (26) | 181 | 2006 | L |
| Mo Vaughn (32) | 181 | 2000 | L | |
| 25. | Mike Schmidt+ (25) | 180 | 1975 | R |
| 26. | Rob Deer (25) | 179 | 1986 | R |
| 27. | Richie Sexson (26) | 178 | 2001 | R |
| 28. | Mark Bellhorn (29) | 177 | 2004 | B |
| Adam Dunn (29) | 177 | 2009 | L | |
| Jose Hernandez (33) | 177 | 2003 | R | |
| 31. | Mike Cameron (29) | 176 | 2002 | R |
| 32. | Jay Buhner (32) | 175 | 1997 | R |
| Jose Canseco (21) | 175 | 1986 | R | |
| Rob Deer (30) | 175 | 1991 | R | |
| Dave Nicholson (23) | 175 | 1963 | R | |
| Gorman Thomas (28) | 175 | 1979 | R | |
| 37. | Curtis Granderson (25) | 174 | 2006 | L |
| Sammy Sosa (28) | 174 | 1997 | R | |
| 39. | Bo Jackson (26) | 172 | 1989 | R |
| Adam LaRoche (30) | 172 | 2010 | L | |
| Jim Presley (24) | 172 | 1986 | R | |
| 42. | Reggie Jackson+ (22) | 171 | 1968 | L |
| Sammy Sosa (29) | 171 | 1998 | R | |
| Sammy Sosa (30) | 171 | 1999 | R | |
| Jim Thome (28) | 171 | 1999 | L | |
| Jim Thome (29) | 171 | 2000 | L | |
| Dan Uggla (28) | 171 | 2008 | R | |
| 48. | Adam Dunn (22) | 170 | 2002 | L |
| Brandon Inge (32) | 170 | 2009 | R | |
| Austin Jackson (23) | 170 | 2010 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Matt Kemp (25) | 170 | 2010 | R | |
| Gorman Thomas (29) | 170 | 1980 | R | |
| 53. | Rob Deer (32) | 169 | 1993 | R |
| Andres Galarraga (29) | 169 | 1990 | R | |
| Craig Wilson (27) | 169 | 2004 | R | |
| 56. | Adam Dunn (25) | 168 | 2005 | L |
| Pete Incaviglia (23) | 168 | 1987 | R | |
| Corey Patterson (24) | 168 | 2004 | L | |
| Juan Samuel (23) | 168 | 1984 | R | |
| Sammy Sosa (31) | 168 | 2000 | R | |
| Drew Stubbs (25) | 168 | 2010 | R | |
| 62. | Jim Edmonds (30) | 167 | 2000 | L |
| Richie Sexson (30) | 167 | 2005 | R | |
| Dan Uggla (27) | 167 | 2007 | R | |
| 65. | Gary Alexander (25) | 166 | 1978 | R |
| Steve Balboni (28) | 166 | 1985 | R | |
| Carlos Pena (30) | 166 | 2008 | L | |
| Cory Snyder (24) | 166 | 1987 | R | |
| 69. | Adam Dunn (27) | 165 | 2007 | L |
| Chris Young (24) | 165 | 2008 | R | |
| 71. | Jack Cust (28) | 164 | 2007 | L |
| Adam Dunn (28) | 164 | 2008 | L | |
| Derrek Lee (26) | 164 | 2002 | R | |
| B.J. Upton (25) | 164 | 2010 | R | |
| 75. | Donn Clendenon (32) | 163 | 1968 | R |
| Troy Glaus (23) | 163 | 2000 | R | |
| Carlos Pena (31) | 163 | 2009 | L | |
| 78. | Jason Bay (30) | 162 | 2009 | R |
| Pat Burrell (24) | 162 | 2001 | R | |
| Ron Gant (32) | 162 | 1997 | R | |
| Bill Hall (26) | 162 | 2006 | R | |
| Butch Hobson (25) | 162 | 1977 | R | |
| Juan Samuel (26) | 162 | 1987 | R | |
| 84. | Dick Allen (26) | 161 | 1968 | R |
| Reggie Jackson+ (25) | 161 | 1971 | L | |
| Brad Wilkerson (25) | 161 | 2002 | L | |
| David Wright (27) | 161 | 2010 | R | |
| 88. | Pat Burrell (28) | 160 | 2005 | R |
| Mike Cameron (34) | 160 | 2007 | R | |
| Henry Rodriguez (28) | 160 | 1996 | L | |
| Alfonso Soriano (30) | 160 | 2006 | R | |
| Mickey Tettleton (29) | 160 | 1990 | B | |
| 93. | Jay Buhner (31) | 159 | 1996 | R |
| Jose Canseco (33) | 159 | 1998 | R | |
| Ben Grieve (25) | 159 | 2001 | L | |
| Mark McGwire (33) | 159 | 1997 | R | |
| Richie Sexson (25) | 159 | 2000 | R | |
| 98. | Jeromy Burnitz (29) | 158 | 1998 | L |
| Jose Canseco (25) | 158 | 1990 | R | |
| Rob Deer (28) | 158 | 1989 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Andres Galarraga (28) | 158 | 1989 | R | |
| Troy Glaus (24) | 158 | 2001 | R | |
| Bo Jackson (24) | 158 | 1987 | R | |
| Melvin Nieves (24) | 158 | 1996 | B | |
| Carlos Pena (32) | 158 | 2010 | L | |
| 106. | Jose Canseco (22) | 157 | 1987 | R |
| Andres Galarraga (35) | 157 | 1996 | R | |
| Ryan Howard (30) | 157 | 2010 | L | |
| Melvin Nieves (25) | 157 | 1997 | B | |
| Jim Presley (25) | 157 | 1987 | R | |
| Alfonso Soriano (26) | 157 | 2002 | R | |
| Lee Stevens (33) | 157 | 2001 | L | |
| Danny Tartabull (23) | 157 | 1986 | R | |
| 114. | Tommie Agee (27) | 156 | 1970 | R |
| Tony Armas (30) | 156 | 1984 | R | |
| Jason Bay (27) | 156 | 2006 | R | |
| Mike Cameron (36) | 156 | 2009 | R | |
| Reggie Jackson+ (36) | 156 | 1982 | L | |
| Dave Kingman (33) | 156 | 1982 | R | |
| Danny Tartabull (30) | 156 | 1993 | R | |
| Jayson Werth (30) | 156 | 2009 | R | |
| Preston Wilson (24) | 156 | 1999 | R | |
| 123. | Jeff Burroughs (24) | 155 | 1975 | R |
| Mike Cameron (28) | 155 | 2001 | R | |
| Frank Howard (30) | 155 | 1967 | R | |
| Mark McGwire (34) | 155 | 1998 | R | |
| Grady Sizemore (24) | 155 | 2007 | L | |
| Brad Wilkerson (26) | 155 | 2003 | L | |
| 129. | Dean Palmer (23) | 154 | 1992 | R |
| Dean Palmer (24) | 154 | 1993 | R | |
| Larry Parrish (33) | 154 | 1987 | R | |
| Richie Sexson (31) | 154 | 2006 | R | |
| Willie Stargell+ (31) | 154 | 1971 | L | |
| B.J. Upton (22) | 154 | 2007 | R | |
| Mo Vaughn (28) | 154 | 1996 | L | |
| Mo Vaughn (29) | 154 | 1997 | L | |
| 137. | Pat Burrell (25) | 153 | 2002 | R |
| Rob Deer (27) | 153 | 1988 | R | |
| Andres Galarraga (27) | 153 | 1988 | R | |
| Pete Incaviglia (24) | 153 | 1988 | R | |
| Matt Kemp (23) | 153 | 2008 | R | |
| Dave Kingman (26) | 153 | 1975 | R | |
| Dean Palmer (30) | 153 | 1999 | R | |
| Grady Sizemore (23) | 153 | 2006 | L | |
| Sammy Sosa (32) | 153 | 2001 | R | |
| 146. | Jose Canseco (26) | 152 | 1991 | R |
| Larry Hisle (22) | 152 | 1969 | R | |
| Geoff Jenkins (29) | 152 | 2004 | L | |
| Jhonny Peralta (24) | 152 | 2006 | R | |
| George Scott (22) | 152 | 1966 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Nick Swisher (25) | 152 | 2006 | B | |
| B.J. Upton (24) | 152 | 2009 | R | |
| Justin Upton (22) | 152 | 2010 | R | |
| Brad Wilkerson (27) | 152 | 2004 | L | |
| 155. | Russell Branyan (26) | 151 | 2002 | L |
| Shin-Soo Choo (26) | 151 | 2009 | L | |
| Delino DeShields (22) | 151 | 1991 | L | |
| Cecil Fielder (27) | 151 | 1991 | R | |
| Cecil Fielder (28) | 151 | 1992 | R | |
| Ray Lankford (31) | 151 | 1998 | L | |
| Don Lock (26) | 151 | 1963 | R | |
| Greg Luzinski (24) | 151 | 1975 | R | |
| Jorge Posada (28) | 151 | 2000 | B | |
| Juan Samuel (27) | 151 | 1988 | R | |
| Richie Sexson (28) | 151 | 2003 | R | |
| 166. | Dick Allen (23) | 150 | 1965 | R |
| Jesse Barfield (29) | 150 | 1989 | R | |
| Jesse Barfield (30) | 150 | 1990 | R | |
| Jeromy Burnitz (32) | 150 | 2001 | L | |
| Nate Colbert (24) | 150 | 1970 | R | |
| Chris Davis (23) | 150 | 2009 | L | |
| Jim Edmonds (34) | 150 | 2004 | L | |
| Brandon Inge (30) | 150 | 2007 | R | |
| Ron Kittle (25) | 150 | 1983 | R | |
| Sammy Sosa (21) | 150 | 1990 | R | |
| Dan Uggla (29) | 150 | 2009 | R | |
| Mo Vaughn (27) | 150 | 1995 | L | |
| 178. | Hank Blalock (23) | 149 | 2004 | L |
| Russell Branyan (33) | 149 | 2009 | L | |
| Travis Fryman (22) | 149 | 1991 | R | |
| Alex Gonzalez (28) | 149 | 2001 | R | |
| Billy Grabarkewitz (24) | 149 | 1970 | R | |
| Fred McGriff (24) | 149 | 1988 | L | |
| Henry Rodriguez (29) | 149 | 1997 | L | |
| Mike Schmidt+ (26) | 149 | 1976 | R | |
| Dan Uggla (30) | 149 | 2010 | R | |
| 187. | Bobby Bonds (27) | 148 | 1973 | R |
| Miguel Cabrera (21) | 148 | 2004 | R | |
| Kelly Johnson (28) | 148 | 2010 | L | |
| Roberto Kelly (25) | 148 | 1990 | R | |
| Ray Lankford (33) | 148 | 2000 | L | |
| Colby Rasmus (23) | 148 | 2010 | L | |
| Mike Schmidt+ (33) | 148 | 1983 | R | |
| Gorman Thomas (32) | 148 | 1983 | R | |
| Preston Wilson (30) | 148 | 2005 | R | |
| 196. | Rob Deer (29) | 147 | 1990 | R |
| Benji Gil (22) | 147 | 1995 | R | |
| Andruw Jones (27) | 147 | 2004 | R | |
| Ray Lankford (25) | 147 | 1992 | L | |
| Phil Nevin (30) | 147 | 2001 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Manny Ramirez (29) | 147 | 2001 | R | |
| Cory Snyder (30) | 147 | 1993 | R | |
| Jim Thome (35) | 147 | 2006 | L | |
| Jim Thome (37) | 147 | 2008 | L | |
| Jayson Werth (31) | 147 | 2010 | R | |
| Brad Wilkerson (28) | 147 | 2005 | L | |
| 207. | Steve Balboni (29) | 146 | 1986 | R |
| Jesse Barfield (26) | 146 | 1986 | R | |
| Jay Buhner (27) | 146 | 1992 | R | |
| Nate Colbert (27) | 146 | 1973 | R | |
| Andres Galarraga (34) | 146 | 1995 | R | |
| Andres Galarraga (37) | 146 | 1998 | R | |
| Todd Hundley (27) | 146 | 1996 | B | |
| Pete Incaviglia (26) | 146 | 1990 | R | |
| Bo Jackson (25) | 146 | 1988 | R | |
| Deron Johnson (32) | 146 | 1971 | R | |
| Ryan Ludwick (29) | 146 | 2008 | R | |
| Dean Palmer (31) | 146 | 2000 | R | |
| Carlos Pena (26) | 146 | 2004 | L | |
| Jhonny Peralta (25) | 146 | 2007 | R | |
| Ed Sprague (28) | 146 | 1996 | R | |
| Jim Thome (26) | 146 | 1997 | L | |
| 223. | Mike Cameron (26) | 145 | 1999 | R |
| Jack Clark (33) | 145 | 1989 | R | |
| Bobby Darwin (29) | 145 | 1972 | R | |
| Troy Glaus (28) | 145 | 2005 | R | |
| Brad Hawpe (30) | 145 | 2009 | L | |
| Jose Hernandez (29) | 145 | 1999 | R | |
| Ray Lankford (34) | 145 | 2001 | L | |
| Lee May (29) | 145 | 1972 | R | |
| Dale Murphy (22) | 145 | 1978 | R | |
| David Ortiz (34) | 145 | 2010 | L | |
| Dean Palmer (27) | 145 | 1996 | R | |
| Jose Valentin (26) | 145 | 1996 | B | |
| Mo Vaughn (34) | 145 | 2002 | L | |
| Chris Young (26) | 145 | 2010 | R | |
| 237. | Dick Allen (27) | 144 | 1969 | R |
| Mark Bellhorn (27) | 144 | 2002 | B | |
| Jay Buhner (28) | 144 | 1993 | R | |
| Tony Clark (25) | 144 | 1997 | B | |
| Travis Fryman (23) | 144 | 1992 | R | |
| Troy Glaus (25) | 144 | 2002 | R | |
| Bobby Knoop (27) | 144 | 1966 | R | |
| Adam Lind (26) | 144 | 2010 | L | |
| Sammy Sosa (33) | 144 | 2002 | R | |
| Dick Stuart (30) | 144 | 1963 | R | |
| Jim Thome (33) | 144 | 2004 | L | |
| Mo Vaughn (30) | 144 | 1998 | L | |
| 249. | Jesse Barfield (25) | 143 | 1985 | R |
| Byron Browne (23) | 143 | 1966 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Mike Cameron (31) | 143 | 2004 | R | |
| Troy Glaus (22) | 143 | 1999 | R | |
| Juan Gonzalez (22) | 143 | 1992 | R | |
| Dave Kingman (28) | 143 | 1977 | R | |
| Nelson Mathews (22) | 143 | 1964 | R | |
| Rick Monday (22) | 143 | 1968 | L | |
| Jorge Posada (30) | 143 | 2002 | B | |
| Ruben Rivera (25) | 143 | 1999 | R | |
| Sammy Sosa (34) | 143 | 2003 | R | |
| Gorman Thomas (31) | 143 | 1982 | R | |
| 261. | Jason Bay (26) | 142 | 2005 | R |
| Pat Burrell (26) | 142 | 2003 | R | |
| Mike Cameron (33) | 142 | 2006 | R | |
| Mike Cameron (35) | 142 | 2008 | R | |
| Donn Clendenon (30) | 142 | 1966 | R | |
| Cito Gaston (26) | 142 | 1970 | R | |
| Carlos Gomez (22) | 142 | 2008 | R | |
| Adrian Gonzalez (26) | 142 | 2008 | L | |
| Shawn Green (25) | 142 | 1998 | L | |
| Reggie Jackson+ (23) | 142 | 1969 | L | |
| Andruw Jones (24) | 142 | 2001 | R | |
| Harmon Killebrew+ (26) | 142 | 1962 | R | |
| Adam LaRoche (29) | 142 | 2009 | L | |
| Lee May (26) | 142 | 1969 | R | |
| Dale Murphy (33) | 142 | 1989 | R | |
| Corey Patterson (22) | 142 | 2002 | L | |
| Carlos Pena (29) | 142 | 2007 | L | |
| Tim Salmon (28) | 142 | 1997 | R | |
| Juan Samuel (25) | 142 | 1986 | R | |
| Jim Wynn (27) | 142 | 1969 | R | |
| 281. | Jesse Barfield (27) | 141 | 1987 | R |
| Jason Bay (28) | 141 | 2007 | R | |
| Bobby Bonds (31) | 141 | 1977 | R | |
| Jack Clark (32) | 141 | 1988 | R | |
| Bobby Crosby (24) | 141 | 2004 | R | |
| Carlos Delgado (27) | 141 | 1999 | L | |
| Andres Galarraga (36) | 141 | 1997 | R | |
| Curtis Granderson (26) | 141 | 2007 | L | |
| Curtis Granderson (28) | 141 | 2009 | L | |
| Frank Howard (31) | 141 | 1968 | R | |
| Reggie Jackson+ (38) | 141 | 1984 | L | |
| Mark McGwire (35) | 141 | 1999 | R | |
| Dale Murphy (29) | 141 | 1985 | R | |
| Dale Murphy (30) | 141 | 1986 | R | |
| Scott Rolen (23) | 141 | 1998 | R | |
| Juan Samuel (24) | 141 | 1985 | R | |
| Darryl Strawberry (24) | 141 | 1986 | L | |
| Jim Thome (25) | 141 | 1996 | L | |
| Jim Thome (27) | 141 | 1998 | L | |
| Jake Wood (24) | 141 | 1961 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Chris Young (23) | 141 | 2007 | R | |
| 302. | Michael Bourn (26) | 140 | 2009 | L |
| Jason Giambi (32) | 140 | 2003 | L | |
| Adrian Gonzalez (25) | 140 | 2007 | L | |
| Corey Hart (28) | 140 | 2010 | R | |
| Jose Hernandez (28) | 140 | 1998 | R | |
| Brandon Inge (28) | 140 | 2005 | R | |
| Reggie Jackson+ (37) | 140 | 1983 | L | |
| Dave Kingman (23) | 140 | 1972 | R | |
| Evan Longoria (23) | 140 | 2009 | R | |
| Greg Luzinski (26) | 140 | 1977 | R | |
| Preston Wilson (27) | 140 | 2002 | R | |
| David Wright (26) | 140 | 2009 | R | |
| 314. | Steve Balboni (27) | 139 | 1984 | R |
| Casey Blake (30) | 139 | 2004 | R | |
| Pat Burrell (23) | 139 | 2000 | R | |
| Jack Clark (31) | 139 | 1987 | R | |
| Carlos Delgado (24) | 139 | 1996 | L | |
| Carlos Delgado (26) | 139 | 1998 | L | |
| Jim Edmonds (35) | 139 | 2005 | L | |
| Cecil Fielder (32) | 139 | 1996 | R | |
| Chase Headley (26) | 139 | 2010 | B | |
| Larry Hisle (23) | 139 | 1970 | R | |
| Matt Kemp (24) | 139 | 2009 | R | |
| Kevin Kouzmanoff (26) | 139 | 2008 | R | |
| Ron LeFlore (27) | 139 | 1975 | R | |
| Alex Rodriguez (29) | 139 | 2005 | R | |
| Alex Rodriguez (30) | 139 | 2006 | R | |
| Tim Salmon (31) | 139 | 2000 | R | |
| Jared Sandberg (24) | 139 | 2002 | R | |
| Nick Swisher (29) | 139 | 2010 | B | |
| Mickey Tettleton (32) | 139 | 1993 | B | |
| Jim Thome (31) | 139 | 2002 | L | |
| Jose Valentin (34) | 139 | 2004 | B | |
| Preston Wilson (28) | 139 | 2003 | R | |
| 336. | Bobby Abreu (32) | 138 | 2006 | L |
| Dick Allen (22) | 138 | 1964 | R | |
| Casey Blake (36) | 138 | 2010 | R | |
| Jose Cruz (27) | 138 | 2001 | B | |
| Ike Davis (23) | 138 | 2010 | L | |
| Kevin Elster (31) | 138 | 1996 | R | |
| Prince Fielder (25) | 138 | 2009 | L | |
| Prince Fielder (26) | 138 | 2010 | L | |
| George Foster (29) | 138 | 1978 | R | |
| Jeremy Hermida (24) | 138 | 2008 | L | |
| Eric Hinske (24) | 138 | 2002 | L | |
| Reggie Jackson+ (39) | 138 | 1985 | L | |
| Geoff Jenkins (30) | 138 | 2005 | L | |
| Andruw Jones (30) | 138 | 2007 | R | |
| Jim Lemon (28) | 138 | 1956 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Jerry Martin (33) | 138 | 1982 | R | |
| Scott Rolen (22) | 138 | 1997 | R | |
| Mike Schmidt+ (24) | 138 | 1974 | R | |
| Ian Stewart (24) | 138 | 2009 | L | |
| Matt Williams (24) | 138 | 1990 | R | |
| 356. | Bobby Abreu (27) | 137 | 2001 | L |
| Tommie Agee (26) | 137 | 1969 | R | |
| Shane Andrews (26) | 137 | 1998 | R | |
| Jason Bay (29) | 137 | 2008 | R | |
| Bobby Bonds (25) | 137 | 1971 | R | |
| Bobby Bonds (26) | 137 | 1972 | R | |
| Bobby Bonds (29) | 137 | 1975 | R | |
| Mike Cameron (30) | 137 | 2003 | R | |
| Bobby Darwin (30) | 137 | 1973 | R | |
| Carlos Delgado (31) | 137 | 2003 | L | |
| Kirk Gibson (28) | 137 | 1985 | L | |
| Alex Gordon (23) | 137 | 2007 | L | |
| Franklin Gutierrez (27) | 137 | 2010 | R | |
| Brad Hawpe (28) | 137 | 2007 | L | |
| Brook Jacoby (26) | 137 | 1986 | R | |
| Ron Kittle (26) | 137 | 1984 | R | |
| Don Lock (27) | 137 | 1964 | R | |
| Mike Marshall (25) | 137 | 1985 | R | |
| Mike Napoli (28) | 137 | 2010 | R | |
| Ruben Rivera (26) | 137 | 2000 | R | |
| Reggie Sanders (30) | 137 | 1998 | R | |
| Mickey Tettleton (31) | 137 | 1992 | B | |
| Mickey Tettleton (35) | 137 | 1996 | B | |
| Justin Upton (21) | 137 | 2009 | R | |
| Greg Vaughn (33) | 137 | 1999 | R | |
| Jim Wynn (25) | 137 | 1967 | R | |
| 382. | Dick Allen (24) | 136 | 1966 | R |
| Jay Bruce (23) | 136 | 2010 | L | |
| Pat Burrell (31) | 136 | 2008 | R | |
| Donn Clendenon (27) | 136 | 1963 | R | |
| Carlos Delgado (29) | 136 | 2001 | L | |
| Jim Edmonds (31) | 136 | 2001 | L | |
| Alex Gonzalez (29) | 136 | 2002 | R | |
| Pancho Herrera (26) | 136 | 1960 | R | |
| Pete Incaviglia (25) | 136 | 1989 | R | |
| Bobby Knoop (28) | 136 | 1967 | R | |
| Dale Murphy (31) | 136 | 1987 | R | |
| Mike Schmidt+ (23) | 136 | 1973 | R | |
| Richie Sexson (27) | 136 | 2002 | R | |
| Dick Stuart (32) | 136 | 1965 | R | |
| Danny Tartabull (24) | 136 | 1987 | R | |
| 397. | Jeff Bagwell (33) | 135 | 2001 | R |
| Carlos Beltran (25) | 135 | 2002 | B | |
| Bobby Bonds (33) | 135 | 1979 | R | |
| Bret Boone (35) | 135 | 2004 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Jeromy Burnitz (33) | 135 | 2002 | L | |
| Jose Canseco (34) | 135 | 1999 | R | |
| Jeff Conine (27) | 135 | 1993 | R | |
| Chili Davis (33) | 135 | 1993 | B | |
| Carlos Gonzalez (24) | 135 | 2010 | L | |
| Reggie Jackson+ (24) | 135 | 1970 | L | |
| Geoff Jenkins (25) | 135 | 2000 | L | |
| Andruw Jones (25) | 135 | 2002 | R | |
| Austin Kearns (26) | 135 | 2006 | R | |
| Harmon Killebrew+ (28) | 135 | 1964 | R | |
| Dave Kingman (27) | 135 | 1976 | R | |
| Greg Luzinski (22) | 135 | 1973 | R | |
| Greg Luzinski (27) | 135 | 1978 | R | |
| Lee May (28) | 135 | 1971 | R | |
| Fred McGriff (27) | 135 | 1991 | L | |
| Adolfo Phillips (24) | 135 | 1966 | R | |
| Tony Phillips (36) | 135 | 1995 | B | |
| Tim Salmon (24) | 135 | 1993 | R | |
| Sammy Sosa (24) | 135 | 1993 | R | |
| Nick Swisher (27) | 135 | 2008 | B | |
| Devon White (24) | 135 | 1987 | B | |
| Devon White (28) | 135 | 1991 | B | |
| 423. | Bobby Abreu (31) | 134 | 2005 | L |
| Bobby Bonds (28) | 134 | 1974 | R | |
| Phil Bradley (27) | 134 | 1986 | R | |
| Lou Brock+ (27) | 134 | 1966 | L | |
| Eric Davis (25) | 134 | 1987 | R | |
| Russ Davis (28) | 134 | 1998 | R | |
| Vince DiMaggio (25) | 134 | 1938 | R | |
| Mike Easler (33) | 134 | 1984 | L | |
| Jim Edmonds (32) | 134 | 2002 | L | |
| Prince Fielder (24) | 134 | 2008 | L | |
| Troy Glaus (29) | 134 | 2006 | R | |
| Brad Hawpe (29) | 134 | 2008 | L | |
| Brandon Inge (33) | 134 | 2010 | R | |
| Derrek Lee (34) | 134 | 2010 | R | |
| Candy Maldonado (29) | 134 | 1990 | R | |
| Raul Mondesi (28) | 134 | 1999 | R | |
| Dale Murphy (26) | 134 | 1982 | R | |
| Dale Murphy (28) | 134 | 1984 | R | |
| David Ortiz (33) | 134 | 2009 | L | |
| Dean Palmer (28) | 134 | 1997 | R | |
| Dean Palmer (29) | 134 | 1998 | R | |
| Jhonny Peralta (27) | 134 | 2009 | R | |
| Tony Perez+ (28) | 134 | 1970 | R | |
| Cory Snyder (26) | 134 | 1989 | R | |
| Sammy Sosa (26) | 134 | 1995 | R | |
| Sammy Sosa (27) | 134 | 1996 | R | |
| Jim Thome (36) | 134 | 2007 | L | |
| B.J. Upton (23) | 134 | 2008 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| 451. | Bobby Abreu (24) | 133 | 1998 | L |
| Mike Cameron (27) | 133 | 2000 | R | |
| Jack Clark (35) | 133 | 1991 | R | |
| Tony Clark (27) | 133 | 1999 | B | |
| Carlos Delgado (25) | 133 | 1997 | L | |
| Chase Headley (25) | 133 | 2009 | B | |
| Reggie Jackson+ (29) | 133 | 1975 | L | |
| Reggie Jackson+ (32) | 133 | 1978 | L | |
| Charles Johnson (29) | 133 | 2001 | R | |
| Jeff Kent (29) | 133 | 1997 | R | |
| Ray Lankford (29) | 133 | 1996 | L | |
| Dale Murphy (24) | 133 | 1980 | R | |
| David Ortiz (28) | 133 | 2004 | L | |
| Juan Samuel (30) | 133 | 1991 | R | |
| Kelly Shoppach (28) | 133 | 2008 | R | |
| Paul Sorrento (32) | 133 | 1998 | L | |
| Sammy Sosa (35) | 133 | 2004 | R | |
| Dale Sveum (23) | 133 | 1987 | B | |
| Gorman Thomas (27) | 133 | 1978 | R | |
| Robby Thompson (27) | 133 | 1989 | R | |
| Devon White (29) | 133 | 1992 | B | |
| Chris Young (25) | 133 | 2009 | R | |
| 473. | Bobby Abreu (36) | 132 | 2010 | L |
| Jay Bell (33) | 132 | 1999 | R | |
| Hank Blalock (24) | 132 | 2005 | L | |
| Russell Branyan (25) | 132 | 2001 | L | |
| Rico Brogna (29) | 132 | 1999 | L | |
| Jeff Francoeur (22) | 132 | 2006 | R | |
| Mike Jacobs (28) | 132 | 2009 | L | |
| Deron Johnson (31) | 132 | 1970 | R | |
| Fred McGriff (25) | 132 | 1989 | L | |
| Gary Pettis (28) | 132 | 1986 | B | |
| Tony Phillips (37) | 132 | 1996 | B | |
| Jorge Posada (29) | 132 | 2001 | B | |
| Grady Sizemore (22) | 132 | 2005 | L | |
| Lee Stevens (31) | 132 | 1999 | L | |
| Chase Utley (27) | 132 | 2006 | L | |
| 488. | Tony Armas (29) | 131 | 1983 | R |
| Jeff Bagwell (36) | 131 | 2004 | R | |
| Russell Branyan (34) | 131 | 2010 | L | |
| Pat Burrell (29) | 131 | 2006 | R | |
| Rob Deer (31) | 131 | 1992 | R | |
| Jack Hannahan (28) | 131 | 2008 | L | |
| Wes Helms (27) | 131 | 2003 | R | |
| Dave Henderson (30) | 131 | 1989 | R | |
| Akinori Iwamura (29) | 131 | 2008 | L | |
| Dave Kingman (30) | 131 | 1979 | R | |
| Adam LaRoche (27) | 131 | 2007 | L | |
| Derrek Lee (27) | 131 | 2003 | R | |
| Mark McGwire (23) | 131 | 1987 | R | |
| Rank | Player (age that year) | Strikeouts | Year | Bats |
| Lyle Overbay (33) | 131 | 2010 | L | |
| Tony Perez+ (27) | 131 | 1969 | R | |
| Doug Rader (29) | 131 | 1974 | R | |
| Manny Ramirez (27) | 131 | 1999 | R | |
| Alex Rodriguez (25) | 131 | 2001 | R | |
| Alex Rodriguez (28) | 131 | 2004 | R | |
| Mike Schmidt+ (32) | 131 | 1982 | R | |
| Darryl Strawberry (22) | 131 | 1984 | L | |
| Nick Swisher (26) | 131 | 2007 | B | |
| Mark Teahen (26) | 131 | 2008 | L | |
| Mickey Tettleton (30) | 131 | 1991 | B | |
| Jim Wynn (26) | 131 | 1968 | R |
Note that seasons prior to 1876 are not included in single-season marks, but are included in career marks.
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