Robert Gentleman

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Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Program in Computational Biology
HeadAppointed: 2004
Harvard University
Adjunct Associate ProfessorAppointed: 2005
University of Washington
College of Arts and Sciences
Adjunct ProfessorAppointed: 2004

Mailing Address

Program in Computational Biology
Division of Public Health Sciences
1100 Fairview Ave. N, M2-B876
P.O. Box 19024
Seattle, Washington 98109-1024
United States

Contact Information

Phone: (206) 667-7700


Ph.D., University of Washington, Statistics, 1988.
M.Sc., University of Washington, Statistics, 1986.
B.Sc., University of British Columbia, Mathematics, 1984.


COS Keywords:

Cancer Or Carcinogenesis, Computational Biology, Public Health.

Previous Positions

2000-2004, Associate Professor, Dana-Farber Cancer Institute and Harvard University, Department of Biostatistics
1999-2000, Visiting Scholar, Harvard University, School of Public Health, Department of Biostatistics
1998-2000, Senior Research Fellow, University of Auckland, Clinical Trials Research Unit, Department of Medicine
1996-2000, Senior Lecturer, University of Auckland, Department of Statistics
1992-1996, Lecturer, University of Auckland, Department of Mathematics and Statistics
1988-1992, Assistant Professor, University of Waterloo, Department of Statistics and Actuarial Science


  • Scholtens D, Vidal M, Gentleman R (Sep 2005) Local modeling of global interactome networks., Bioinformatics (oxford, England), 21 (17), 3548-57 Abstract
  • Gurvich N, Berman MG, Wittner BS, Gentleman RC, Klein PS, Green JB (Jul 2005) Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo., The Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology., 19 (9), 1166-8 Abstract
  • Tadesse MG, Ibrahim JG, Gentleman R, Chiaretti S, Ritz J, Foa R (Jun 2005) Bayesian error-in-variable survival model for the analysis of GeneChip arrays., Biometrics, 61 (2), 488-97 Abstract
  • Tadesse MG, Ibrahim JG, Vannucci M, Gentleman R (Mar 2005) Wavelet thresholding with bayesian false discovery rate control., Biometrics, 61 (1), 25-35 Abstract
  • Carey VJ, Gentry J, Whalen E, Gentleman R (Jan 2005) Network structures and algorithms in Bioconductor., Bioinformatics (oxford, England), 21 (1), 135-6 Abstract
  • Balasubramanian R, LaFramboise T, Scholtens D, Gentleman R (Dec 2004) A graph-theoretic approach to testing associations between disparate sources of functional genomics data., Bioinformatics (oxford, England), 20 (18), 3353-62 Abstract
  • Tengs T, LaFramboise T, Den RB, Hayes DN, Zhang J, DebRoy S, Gentleman RC, O'Neill K, Birren B, Meyerson M (Aug 2004) Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments., Nucleic Acids Research, 32 (15), e121 Abstract
  • Huber W, Gentleman R (Jul 2004) matchprobes: a Bioconductor package for the sequence-matching of microarray probe elements., Bioinformatics (oxford, England), 20 (10), 1651-2 Abstract
  • Chiaretti S, Li X, Gentleman R, Vitale A, Vignetti M, Mandelli F, Ritz J, Foa R (Apr 2004) Gene expression profile of adult T-cell acute lymphocytic leukemia identifies distinct subsets of patients with different response to therapy and survival., Blood, 103 (7), 2771-8 Abstract
  • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J (2004) Bioconductor: open software development for computational biology and bioinformatics., Genome Biology, 5 (10), R80 Abstract
  • Christopher K, Mueller TF, DeFina R, Liang Y, Zhang J, Gentleman R, Perkins DL (Sep 2003) The graft response to transplantation: a gene expression profile analysis., Physiological Genomics, 15 (1), 52-64 Abstract
  • Dudoit S, Gentleman RC, Quackenbush J (Mar 2003) Open source software for the analysis of microarray data., Biotechniques, Suppl, 45-51 Abstract
  • Zhang J, Carey V, Gentleman R (Jan 2003) An extensible application for assembling annotation for genomic data., Bioinformatics (oxford, England), 19 (1), 155-6 Abstract
  • Mutter GL, Baak JP, Fitzgerald JT, Gray R, Neuberg D, Kust GA, Gentleman R, Gullans SR, Wei LJ, Wilcox M (Nov 2001) Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation., Gynecologic Oncology, 83 (2), 177-85 Abstract
  • Gentleman RC, Lawless JF, Lindsey JC, Yan P (Apr 1994) Multi-state Markov models for analysing incomplete disease history data with illustrations for HIV disease., Statistics in Medicine, 13 (8), 805-21 Abstract
  • Gentleman R, Crowley JJ (1992) A graphical approach to the analysis of censored data., Breast Cancer Research and Treatment, 22 (3), 229-40 Abstract
  • Gentleman R, Crowley J (Dec 1991) Local full likelihood estimation for the proportional hazards model., Biometrics, 47 (4), 1283-96 Abstract

Profile Details

Last Updated: 9/12/2006

COS Expertise ID #1221830
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