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What is MicroSort?

Increase your chances of conceiving the gender you want through sperm sorting

It’s true. You can increase your chances of having a boy or a girl using MicroSort®—the only scientifically proven way to influence gender prior to conception.

MicroSort is a scientific method used before conception to separate sperm into two categories:

• Sperm that produces girls (X-bearing)
• Sperm that produces boys (Y-bearing)

Why does sperm sorting help gender selection?
Without assistance, most sperm samples are close to 50% X-bearing and 50% Y-bearing. On your own, your chances of having a boy are about equal to your chances of having a girl.

MicroSort can help you increase those odds—whichever way you choose—by producing a high percentage of either X-bearing (girl) or Y-bearing (boy) sperm.

How does MicroSort separate X- and Y-bearing sperm?
The process relies on a difference in the amount of genetic material in X- and Y-bearing sperm. X chromosomes have slightly more DNA than Y chromosomes. Therefore, X-bearing sperm are slightly larger than Y-bearing sperm. MicroSort distinguishes this size difference using a technique called “flow cytometry.”

Here’s how flow cytometry works:

1. Your sperm sample is dosed with a safe fluorescent dye, which temporarily attaches to its DNA. Because X-bearing sperm have slightly more DNA, more of the dye will bind to them than to Y-bearing sperm.
2. The dyed sperm are sent through the flow cytometer, where they travel single-file through a "sheath" fluid.
3. The sperm then pass through a laser, which makes the fluorescent dye glow. Brighter-glowing cells are sorted as X-bearing sperm.
4. The resulting enriched sample is not 100% X or Y, but has a significantly higher percentage of one or the other.

What happens after the sperm is sorted?
For most couples, the sorted sperm are used with simple intrauterine insemination (IUI) to achieve pregnancy. Couples needing additional assistance can use MicroSort with in vitro fertilization (IVF). Process details vary depending on which method you use.

View Flowchart of MicroSort Process

For IUI with MicroSort, simple cycle monitoring tests are performed to determine the time of ovulation. Insemination is performed very close to that time to maximize the opportunity for a pregnancy.

To achieve IUI pregnancy with MicroSort, on the day of ovulation the following steps are performed:

1. Your husband produces a sperm sample.
2. The sample is sorted for the desired gender.
3. Insemination with the sorted specimen occurs later that same day.

To achieve IVF/ICSI pregnancy with MicroSort, on the day of ovulation the following steps are performed:

1. Your husband produces a sperm sample.
2. The sample is sorted for the desired gender.
3. The sorted sample is sent to an embryology laboratory for egg fertilization.

Does MicroSort provide IUI or IVF procedures?
MicroSort only provides the sperm sorting service. You must work with a participating physician to complete conception with IUI or IVF procedures.

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