Philip Rivers threw for 392 yards and three touchdowns, the final one a 26-yarder to Seyi Ajirotutu with 24 seconds remaining, to give San Diego a 41-38 victory over the Kansas City Chiefs.
Tom Brady led an inspired New England Patriots team back from the brink as they reversed a 24-0 half-time deficit to beat the Denver Broncos in overtime.
Colin Kaepernick and the San Francisco 49ers (6-4) head east to take on Robert Griffin III and the rest of the Washington Redskins (3-7) at FedEx Field.
Tony Romo and the embattled Dallas Cowboys took this pivotal game and all but buried New York's play-off hopes.
Authorities say a woman jumped from the third level deck of the Oakland Raiders' home stadium, injuring herself and a man who tried to catch her.
The Packers' losing streak without Aaron Rodgers is over, though the frustration continues in Titletown. A tie did little to lift spirits in Green Bay. Matt Flynn threw for 218 yards and helped spark a rally from a 16-point deficit.
Tampa Bay is turning around its season, relying on a cool and calm rookie quarterback and an opportunistic defense.
The only time the brother vs. brother subplot got really physical was when Chris Long played the role of peacemaker.
Philip Rivers called it the kind of game that could save the Chargers' season. Seyi Ajirotutu called its defining play the greatest catch of his career.
Cam Newton angrily slapped his hands together and stared into the end-zone stands, watching Miami Dolphins fans celebrate his interception.
Carson Palmer threw two touchdown passes to Larry Fitzgerald, Karlos Dansby returned an interception 22 yards for a score and the Cardinals won their fourth in a row with a 40-11 rout of the Colts.
Their horrendous start has been long forgotten, erased with an equally unexpected turnaround. The Steelers are in contention, right back where they belong.
With one drive to determine whether Tennessee or Oakland would move right into the thick of the AFC playoff race, Ryan Fitzpatrick stepped up.
Eleven games into the season, the New York Jets have the kind of problems that are usually addressed in training camp.
When Jacksonville entered its bye week winless, the goal was to turn things around in the second half of the season. So far, so good.
There are overzealous celebrations, and then there is this. New Orleans Saints tight end Jimmy Graham bends the goalposts after scoring the decisive touchdown against their rivals, the Atlanta Falcons.
The New Orleans Saints strengthened their hold on the NFC South after seeing off their divisional rivals the Atlanta Falcons in a close game.
See American football games from every team for the 2013 season, and playoff games streaming live or on demand with an NFL Game Pass.
Kory Sheets ran for a record 197 yards and two touchdowns to leading the Saskatchewan Roughriders over the Hamilton Tiger-Cats 45-23 in the Canadian Football League's 101st Grey Cup championship game.
JAMIE REDKNAPP: Spurs are in a mess, Barkley and Gerrard would have been dreamy for England and why West Ham fans must stop booing Frank
MARTIN SAMUEL: Football League pickpockets are killing dreams
Damages applied to the likes of Blackburn and QPR could crush them
GRAHAM POLL'S WEEKEND VERDICT: Mike Riley may be looking up Mackay's phone number to apologise... Rooney HAD to go for kick
WHAT WE LEARNED THIS WEEKEND: Liverpool's corner strategy doesn't work and Turner's now the game's longest serving manager
JEFF POWELL: One punch too few... but do we really want one too many next time?
Neither Carl Froch nor George Groves wound up seriously hurt
FOOTBALL GRAPEVINE: Ronaldo's United move isn't dead yet, Benteke could be the answer to Arsene's problem, and Balotelli and Mourinho might be reunited
MARTIN SAMUEL VERDICT: England must find some street-fighter toughness and stand up to Johnson's bouncer or Ashes will be surrendered
BUMBLE: I could hear Warner on the stump microphone saying nasty, horrible stuff... it was unacceptable
DAVID LLOYD AT THE GABBA
GARY NEVILLE: I can now see how wrong I was to harass referees
Former Manchester United star on players' behaviour around our officials
Stand and deliver? 20 years after all-seater stadiums arrived in the wake of the Hillsborough disaster, pressure is growing to allow fans to stand again
'Miracle of Heysel' backs return of standing: 'Football is more beautiful that way'
Alessio Degrandi survived Heysel disaster as a 14-year-old boy
Even our WAGs are better looking! Aussie press taunt partners
England have taken a battering on the field... and now their WAGs have been mocked
The Fame Academy: Butt has gone from playing with the Class of '92 to nurturing United's next golden generation
Nicky Butt talks about the Class of '92
Even our sledging's a shambles! The six serious problems that England must address to get back in series
PETER HAYTER: Ashes verdict so far
JAMES ANDERSON: We definitely have character to bounce back
If we've ever lost a Test or been up against the wall, we nearly always bounce back pretty well
MONDAY NIGHT FOOTBALL PREVIEW: Kaepernick and RG3 clash under the lights
The San Francisco 49ers take on the Washington Redskins.
Rugby vow: no cover up! IRB chief promises to make research results public
Brett Gosper has restated his commitment to player welfare
Ten years on since THAT drop goal, Wilkinson has beaten World Cup demons
Ten years on from the night when his drop-goal won the World Cup
The fighter! How Adam Hollioake has rolled with life's punches and learned to be happy
Adam Hollioake rebuilt his life through boxing and cage fighting.
JAMIE CARRAGHER: I was a boy in blue, now I'm a man in red... but Liverpool as a city exists to win trophies and I worry it will be left behind
JAMIE REDKNAPP: Suarez and Baines make my Merseyside XI, but which other Everton and Liverpool stars are in there?
Composite Mersey XI
Barnes and Reid leave Suarez out in the cold as Dean, Rush and Ferguson pip him to Sportsmail's top-10 Merseyside strikers... but who's our No 1?
EXCLUSIVE: Quit? I'm taking on the best managers in Europe. This job is heaven, says Cardiff boss Mackay
Malky Mackay says he wants to stay at Cardiff
Dawson: Tottenham's medical team shouldn't have been criticised over Lloris KO (and pal Hart will bounce back)
Michael Dawson backs Joe Hart to shine
It's top secret! Bayern's Lahm on a treble, his love for the NBA and baking
Philipp Lahm reveals his career highlight and worst moment
JEFF POWELL: As German giants seize the mantle of world football, England caught short
Football never stops evolving but England are being left behind
MARK WEBBER EXCLUSIVE: Aussies will win Ashes 3-1, my love for Man United, and the best F1 driver I faced
Sportsmail caught up with the 37-year-old...
Kop that! Gerrard proves he's still Liverpool's main man
Liverpool captain has created more chances than any other player in the Premier League
Bobble heads, boots, golf clubs, gadgets, trainers... and a toaster! It's all here in our Christmas gift guide
Check out our must-have presents for this year
THE MIDLANDER: The transition was painful, but Lambert finally has Villa bursting with energy... will they keep progressing or stagnate?
We're off to Brazil! Your guide to all the teams who have qualified for World Cup
Sportsmail brings you the complete lowdown on the 32 heading out
She was the whistleblower who hauled him down, Lance Armstrong was the drug cheat - what happened when they were brought together by MailOnline?
Garrett Hartley kicked a 31-yarder as time expired to lift the Saints to victory over the 49ers. Meanwhile, Robbie Gould kicked a 38-yard field goal to lift Chicago to a 23-20 victory over Baltimore in a game delayed about two hours.
The Denver Broncos brought Kansas City's unbeaten start to an end by claiming a crucial victory over their AFC East rivals at Sports Authority Field.
The Seattle Seahawks rolled to their franchise-record 13th straight home win beating the Minnesota Vikings 41-20.
No overtime this time. The Cincinnati Bengals brushed aside their intrastate rival and strengthened their hold on the AFC North.
Cam Newton threw a game-winning touchdown pass to Ted Ginn late in the fourth quarter to seal a sixth straight win.
Nick Foles threw for 298 yards and spun free for a touchdown, LeSean McCoy ran for two scores and the Eagles snapped a 10-game losing skid at Lincoln Financial Field with a victory over Washington.
Backed up and fed up, Ben Roethlisberger provided a vivid reminder to his critics and the Detroit Lions of just how dangerous he remains.
Garrett Hartley kicked a 31-yarder as time expired to lift the New Orleans Saints to a 23-20 victory over the San Francisco 49ers.
Robbie Gould kicked a 38-yard field goal to lift the Chicago Bears to a 23-20 victory over Baltimore in a game delayed by a torrential downpour.
The New York Giants are not only back in the playoff hunt with a four-game winning streak, they're calling the plays that get them those wins.
Ryan Tannehill watched the final play from the sideline, hopping anxiously as an opponent's desperation heave hung in the air.
The Indianapolis Colts once again recovered from a poor first half to beat the Tennessee Titans in Nashville and take control of the AFC South.
For Bills safety Jairus Byrd, there was nothing like the sight of watching Matt Simms trot out on the field early in the fourth quarter.
Carson Palmer completed six passes to six receivers on the Arizona Cardinals' opening drive that led to a touchdown.
Bobby Rainey's never lacked confidence in himself. All he wants is an opportunity to show he can play in the NFL.
Oakland rookie Matt McGloin was so good in a win over the Texans that it raised questions about whether Terrelle Pryor will get his job back.
Keep up to date with all the fixtures and results during the 2013 National Football League season.
Keep up to date with the latest divisional standings during the 2013 National Football League season.
Want to learn more about American Football? Or simply brush up on your knowledge? Find out all there is to know about the game.
Published by Associated Newspapers Ltd
Part of the Daily Mail, The Mail on Sunday & Metro Media Group
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