She has a condition that left her deaf and now is robbing her of her sight. Yesterday, in our first extract from her new book, Jo Milne (left as a child and right today) told of the wonderful moment in 2014 she heard a human voice for the first time at 39. Here, in the final instalment, she recalls how she became a worldwide sensation, how she discovered music - and how she also changed the life of a man who years before had been so cruel to her.

Samantha Bourner, 33, from Kent, spent a traumatic 12 years trying to start a family with her partner David, 35 (the pair are pictured, right). She suffered seven miscarriages and gave up hope of ever having a child. Doctors diagnosed her with Antiphospholipid syndrome, which increases the chance of blood clots and raises the risk of miscarriage in pregnant women. Doctors prescribed daily aspiring and drugs to stop her blood clotting. They also put a stitch in her womb to stop it opening too early, so she could carry a baby to term. When she became pregnant again, she was thrilled, and was delighted to hear it was twins. She lost one of the babies at nine weeks old, and it was absorbed back into the womb. On December 3 2014 she gave birth to Noel Arthur Paul (pictured left), and couldn't be happier. She said: 'We are over the moon with Noel, he really is a miracle and I adore him.'

Pauline Potter, 51, was told that she could develop a fatal blood clot if she didn't get out of bed and start moving after her gastric bypass surgery. Although she claimed she was committed to shedding her excess weight, she said she was still in too much pain to start walking.

Emma Harvey, from Bromley, London, piled on the pounds after living a party lifestyle in Magaluf (left), downing tequila shots and eating fast-food for breakfast and consuming nothing but takeaways. The 23-year-old weighed 15st 4lb when she decided to battle her bulging waistline. Emma, who is now a six 6 (right), even managed to bag herself a personal trainer boyfriend, Leon Hodge (inset), 34, who she met on a night out. The accountant said: 'During those two summers in Magaluf I was eating absolute rubbish and doing no exercise whatsoever. I would wake up at 2pm and have a kebab for breakfast with a shot of tequila. The alcohol there is practically free and I was drinking at least 10 glasses of vodka and lemonade and 12 shots of Sambuca a night. I don't think I had a single glass of water while I was out there.'

Winnie Shapland, 4, of Bideford, Devon, was diagnosed just months after her brother Alfie was diagnosed with leukemia in September 2014. Four months into his chemotherapy treatment, the childrens' mother, Tamar Leat, noticed Winnie had developed a squint. She demanded doctors treating Alfie assess her daughter, and scans revealed a plum-sized non-cancerous tumour in her brain. After 10 hour surgery to remove it, Winnie is now recovering in hospital - and her brother is responding well to chemotherapy. Mrs Leat said: 'It's all been horrendous and I often just burst into tears. Having this happen to one of your children is every parent's worst nightmare - to have it happen to our two beautiful twins is just unthinkable. But Alfie and Winnie have both been amazing. They just take it all in their stride.'

Joanne Richards and Barry Ricketts from Stourbridge, West Midlands, had been overweight since school. The turning point came when Joanne was told she wouldn't make it to 40. The 31-year-old tipped the scales at 24st 5lbs and wore a size 32, while her long-term partner Mr Ricketts, 43, was 21st and wore a six XXXL trouser (pictured left). It was not until Miss Richards' periods stopped and they were both warned that their size was putting a strain on their bodies, that the couple, paired up to lose weight (right). 'I was told I would die by the time I was 40 if I kept going the way I was,' Miss Richards says.

Jack Bristow, nine, from Basingstoke, is fighting for his life after being diagnosed with the disease, which usually affects men three or four times his age. He was taken to see doctors after his right testicle began to swell after he suffered a groin injury playing football. Tests revealed abnormal cells in Jack's testicle and specialists told his parents he was thought to be the youngest person to be diagnosed with testicular cancer. He has had his testicle removed, and undergone two rounds of chemotherapy, causing him to lose his hair. His parents Dan and Joanne (pictured with Jack), hope their son has good chance of surviving after doctors said the cancer is among the most treatable forms of the disease.

Jo Milne, 39, from Gateshead, suffers from Usher syndrome. As well as being deaf, the syndrome also affects her ability to see and Jo has been going blind since her late 20s. Last year she had a risky operation to have cochlear implants to have a chance at hearing for the first time. Thankfully the operation was a success and Jo is now able to hear.

Ashley Daly, 27, of Cumnock, Ayrshire, was referred for an ultrasound when she discovered a lump in her breast, but doctors misdiagnosed the lump as being down to hormones. They carried out no further tests, telling her she was 'too young for breast cancer'. Six months later the lump was visible and her nipple was inverted, and she was diagnosed with cancer that had spread into her lymph nodes. She is now undergoing chemotherapy (she is pictured, left, during treatment) in which she has lost her hair. She is preparing for a double mastectomy which she hopes will allow her to stay alive to raise her young daughter Sophie, four (she is pictured, left, with Sophie, and with her partner, Adam, 29, inset). She now wants to encourage other young women to get themselves checked regularly. She said: 'You need to keep checking regularly, and don't accept age as an excuse for a lump. If you're not sure, always get a second opinionhttp://molwps.andweb.dmgt.net/begin.html#.'

EXCLUSIVE: Part of Margaret Thatcher's formidable reputation was down to how little she slept. The former British prime minister (bottom right) was believed to get by on just four hours of sleep each night - and she wasn't the only one. Barack Obama (top right) currently only gets six hours of rest each night, The infographic (left), created by Berkshire-based Made to Measure Blinds, reveals most of the successful people named are below the recommended levels of sleep of seven to nine hours each night.

Stuart Brookes, 30, from Birmingham (pictured left with his girlfriend Alina Ispavskaya), is battling metastasis myxoid liposarcoma for a second time and is trying to raise £150,000 to travel to the US for treatment after he was given 18 months to live. He was first diagnosed with the disease in November 2012 after visiting his GP complaining of a lump on his right knee. The doctor mistook it for a pulled muscle and over the next three months the lump grew to the size of a fist. Mr Brookes returned to another GP, this time in London after moving, and was referred for a biopsy and MRI scan. The tests revealed he was suffering the rare form of soft tissue cancer. He underwent treatment and surgeons removed the lump (inset). But nine months later, Mr Brookes noticed more lumps on his left leg and back. Tests showed his disease had returned and spread to his hip, spine and pelvis. Doctors gave Mr Brooke (pictured right with his mother Lesley) 18 months to live, but he refused to give up and found a clinical trial in the US he hopes to enrol on.

Twin sisters Binh and Phuoc Wagner of Ontario, Canada (right) suffer from the same genetic condition that is causing their livers to slowly fail. Their adoptive father Michael Wagner found out he was a match for both, but could only donate a portion of his liver to one of the girls. Mr Wagner and wife Johanne decided on Phuoc because she had a more dire medical need than her sister. On February 10, father and daughter underwent the operation at the Hospital for Sick Children in Toronto. They are pictured on the left reuniting five days after the surgery. The family is still looking for a donor for Binh, and the hospital has received 400 submissions from potential donors

While most heart attacks do affect people with classic risk factors such as a sedentary lifestyle, diabetes and obesity, those who lead a virtuous life can suffer one too, says Dr Edward Duncan, consultant cardiologist at the Bristol Heart Institute. So, could you be at risk? Here, five people tell ANGELA EPSTEIN how they fell victim to seemingly unexplained heart attacks, while Dr Duncan explains the hidden risk factors that may have contributed.

Anastasia Shields (main image with son), 23, from Northway, Gloucester, says she has tried everything to get Harvey-Jay (inset) to eat, including sneaking high-fibre milkshakes into his hot chocolate. She hit out at doctors after her son, who weighs just 15lbs - spent 10 days at Gloucestershire Royal Hospital and medics failed to diagnose the problem but said he simply may be a fussy eater. The mother-of-two said his weight loss has left his skin stretchy, pale and he is prone to becoming ill. She believes he may have an 'oral phobia' and wants doctors to do more before they 'end up putting him in a coffin'.

Jake Croft from Barnsley, South Yorkshire was four-and-a-half when he passed away last October. He had complained of 'achy legs' which his mother Claire thought must be growing pains. Six weeks later she took him to the GP and Jake was diagnosed with advanced-stage neuroblastoma, an aggressive children's cancer.

Dean Weiss (left, as a bulkier steroid-taker and centre and right, his transformed physique as a natural body-builder) is considered one of Australia's leading personal trainers, who readily admits to having used steroids. But he says the brutal 'crash and burn' affects of taking performance enhancing drugs, including low sex drive and depression, made him change his ways. The 30-year-old now runs a natural PT business encouraging teenage gym junkies looking for the perfect body to steer clear of steroids.

Kristina Miles, 23, from Ipswich, dropped from a size 24 (inset) to a 14 for her wedding day with Ashley (right) but has been left with the 'body of a granny' (left and centre). She has also been refused surgery to remove it on the NHS. Kristina says she is so unhappy with her current figure that not only does she not feel sexier but she refuses to let her partner see her naked. The slimmer has been turned down for skin removal surgery on the NHS and fears her only option to look attractive again is to gain the weight she lost to save her marriage.

Trish, 49, and Rob Gregory, from Newark, Nottinghamshire, were unable to conceive naturally but gave birth to Darcey, two, and Bea, one, thanks to egg donation. The couple (pictured left with Darcey, left, and Bea, right) are now planning their third baby through egg donation. Trish believed that using the eggs of a younger woman would give her a better chance of getting pregnant. She and Rob tried to conceive naturally after they met 10 years ago (top right). Trish finally fell pregnant and gave birth to Darcey (bottom right) in 2012 after fertility treatment.

We reveal how to get the enviable physiques of the stars. This week: Joan Collins's legs.

Jonny Normal, 47, from Stratford-upon-Avon, Warwickshire, joked that he had 'man flu' when he had a sore throat and a high temperature. But his wife Andrea, 45 (pictured with her husband in the right hand photo), called 999 when he began vomiting. He was rushed to hospital and put in a coma, suffering pneumonia which was affecting his breathing. After two weeks, where doctors nearly turned off his life support machine (he is pictured in a coma, left), he blinked and woke up. He had suffered a stroke and had to learn to speak and walk again, but is now at home. He says he is lucky to have survived and is enjoying time with his family: 'Even just sitting at home watching a DVD with Andrea and the girls is magical, it's something I thought I'd never have again.'

EXCLUSIVE: The man, known only as Sambany, walked all the way across Madagascar to seek help. He said he felt 'dead inside' after the way he'd been treated during his life because of the growth. After learning that the charity Mercy Ships had docked one of their vessels in the Madagascan port of Toamasina, Sambany and his grandson walked for three days, finishing their journey with a four-hour car ride, to see if the team of volunteers aboard Africa Mercy could help. The medics on board performed a 12-hour operation to remove the tumour, the largest they had ever dealt with (right). Catching a glimpse of himself in the mirror for the first time after surgery, Sambany appeared delighted with the results, exclaiming: 'I like it. I am happy.'