Chloe Print-Lambert, 20, from Warwickshire, has a range of debilitating conditions that leave her wheelchair-bound and unable to care for herself (she is pictured, right, with her mother). She developed Ehler-Danlos syndrome, a condition which affects the joints and connective tissues, in 2014. It meant her joints could dislocate at the slightest knock. Then, in 2009, she was diagnosed with a rare heart condition, called postural orthostatic tachycarsida disorder (PoTS). The condition causes abnormal changes in a person's heart rate, so she can collapse if she sits or stands up, as well as suffering seizures. And last year, she unexpectedly began suffering seizures and allergic reactions to different stimuli. After being hospitalised for seven months (pictured left and centre), doctors as mastocytosis, which causes her to develop random allergies and suffer severe reactions. She has already suffered seizures caused by jewellery, medication, temperature change - and even feeling excited - and has no way of knowing what her body will develop an allergy to next. 'I've even developed allergies to my emotions,' she said. 'On Mother's day, I'd been in hospital for weeks, and my whole family were coming to see me. I was so excited, I went out into the corridor to see them, and had a seizure straight away.'

Melissa Sutton, 16, from Rochdale, Lancashire, began suffering from pain in her ribcage and she noticed she was short of breath (she is pictured before her diagnosis, left). She went to her GP, who told her she had pulled a muscle and prescribed antibiotics. In the space of three months, she went to the medical practice a total of 10 times, and four different GPs said it was a sports injury. Eventually the pain became so bad she couldn't lie down, or sleep at night, and her mother, Alison Brookes, 41, took her to A&E.; There, she was diagnosed with the rare bone cancer Ewing's Sarcoma. She had an operation to remove four ribs, and is currently undergoing chemotherapy and radiotherapy at Royal Manchester Children's Hospital (she is pictured in hospital, right, and after losing her hair to chemotherapy, inset). Now, she wants to raise awareness to the disease so other teenagers are aware of the symptoms. She said: 'When I was diagnosed with cancer it was a huge shock. It was news that no teenage girl wants to hear. The treatment has made me very poorly but I am just glad the cancer was detected when it was. I want to raise awareness so that other people who experience the same symptoms don't give up and trust their instincts.'

Bob Cole, 68, (pictured left) who was battling an aggressive form of lung cancer, took a lethal cocktail of drugs just 18 months after he watched his wife Ann, 67, (pictured right with Bob) die in the same way in Switzerland. In a text (inset) sent from his bedside at 2.25pm this afternoon a friend wrote: 'Dear friends, Bob died with smile on his face to Beethoven's Ode to Joy. He asked you all the seize the time'. The former carpenter wanted to publicise his death because he wants MPs to 'have the guts' to decriminalise assisted suicide in Britain. Mr Cole also wrote to his friends to ask for their forgiveness before he travelled to Dignitas to end his life, MailOnline can reveal.

Sam Fitzgerald, 15, from Irthlingborough, Northamptonshire, began suffering bouts of anger 18 months ago (he is pictured, right, with brohter Kai before becoming ill). His mother Jackie Courtney, 41 (pictured left with her son), became worried he wasn't himself and took him to the doctors. As he became increasingly and uncharacteristically irate, she took him back to the medical practice and he saw different doctors on six occasions, who all dismissed his problems as 'moodiness' or 'hormonal'. His hands and toes began to curl and his speech became slurred, and he was sent for a blood test. It revealed he had Wilson's disease, where copper gathers in the liver and brain, leading to fits of rage and a loss of motor control. Now, he is in a wheelchair, unable to walk or eat. Ms Courtney believes had the disease been diagnosed earlier it would not have progressed so rapidly. She said: 'If he had been diagnosed then it wouldn't have got as bad. But they just blamed it on hormones, they said he was a stroppy teenager. I knew it was more than mood swings, but they really wouldn't listen to me.'

This harrowing photograph (main) was shared by Lisa Armitage, 27, after she watched her 'soul mate', Mthuthuzeli Mpongwana, 38, die in a Bristol hospital. Two days earlier, Mr Mpongwana (inset with his wife) had waited nearly six hours for an ambulance after a paramedic dismissed his meningitis symptoms as 'man flu', and downgraded the call's priority. Today, a coroner said there was a 'missed opportunity' to deliver vital treatment to Mr Mpongwana and ruled there were 'failings' in his care.

New Zealand baby Mason Page has surgery to remove his left eye in Auckland on Thursday (right, and inset). Little Mason's mother Sarah Bowers discovered her son's condition when looking at photographs she had taken of him (left). Now doctors will analyse the eyeball to reveal whether the 20-week-old baby had Retinoblastoma, a rare form of eye cancer, or Coats' disease.

Holly Desai, 23, from Leicester, split up with her boyfriend in July 2010 thought eating healthily and doing more exercise would give her a new focus. She downloaded diet and fitness apps, but soon became obsessed, developing anorexia and bulimia. Her weight plummeted to 7.5 stone (pictured centre), but doctors told her she wasn't thin enough for treatment. She continued to lose weight and her BMI reached the dangerously low level of 14.9. She confided in her mother, who helped her beat the disease. Now, back to a healthy 9.5 stone (pictured left), she is competing in the Miss England competition, which she says has boosted her confidence. She wants to warn others about the dangers of becoming obsessed with calorie counting apps. She said: 'When I look back on what I used to be like, I can't believe how far I've come.When I was in the grip of an eating disorder, I didn't see how I would ever come through it, but I'm living proof that things can get better.'

WARNING: GRAPHIC CONTENT. Brody Curtis, four, of Charlestown, Indiana, suffers from epidermolysis bullosa, which means his skin lacks collagen. His body is covered with painful, blistering wounds that will never heal (left and right as a baby). He takes a cocktail of medication every day to ease his agony and he cannot stand, walk or crawl. He must be wrapped from head to toe in bandages, and placed in a medicinal bath for up to four hours three times a week - a process which is excruciating. Life expectancy for the condition varies on the type, but his mother Heather, 37, says he will not live past 20. In a bid to raise awareness to the condition, Mrs Curtis has uploaded a video of her son being bathed. The heartbreaking film shows the infant crying in agony as his body adjusts to the water. She said: 'Hearing our child has an incurable condition that will 99 per cent likely kill him before he reaches 20 was devastating. Our hearts broke. But we've gotten better at dealing with it over time. We try to stay positive and act strong and laugh for Brody, as that will reflect on him and keep him healthier and stronger for longer.'

Mineola, New York, resident Dawn Ardolino Policastro (R), 40, offered to carry the baby of her identical twin sister Allison Ardolino Dinkelacker (L) after a battle with stage three breast cancer during her first pregnancy with son Dylan in 2009 made a second pregnancy too risky.

Victoria Burnham, 35, from Bridlington, began losing weight in January after ballooning to 23st (left). Within six months she had lost 11 stone (right) - almost half her body weight - and had developed anorexia. Although she went to the GP, as she had a healthy BMI, he said she 'didn't have an issue'. She continued to lose weight, becoming too weak to lift up her children, and as she could no longer care for them they were forced to go and live with their father. She would faint if she walked even a short distance, and had to give up her job as a special needs support worker. Now, she is being treated for anorexia at Hull Royal Infirmary, and is calling for more to be done to help people with hidden eating disorders.

From the moment he was born, Howard Shulman was considered an outcast. A bacterial infection ravaged his face, leaving a gaping hole where his nose, lower right eyelid, tear ducts, lips, and palate would have been. His parents, unable to cope with their son's deformity, left him in the hands of the state and he spent the rest of his childhood in foster care. Almost 40 years later, after hundreds of painful operations, he is married, living in San Diego and has two stepdaughters. And, despite the heartbreak of losing his parents as a child, he has revealed in a new book how he tracked his mother down and confronted her.

Arlene Mounce, from Irvine, Ayrshire, can't remember a time when she didn't have a food phobia and has survived solely on chips, white bread, cream crackers and Frosties since the age of four. She was unable to change her diet despite suffering from aneamia, blackouts and memory loss over the years - but was initially dismissed as a 'carb junkie' by her GP. The 32-year-old was finally diagnosed with Selective Eating Disorder (SED) in January and has had hypnotherapy in the hope of developing a healthier diet.

Gemma Rogers, 24, from Cumbernauld, North Lanarkshire, was devastated when she went for her 20-week scan and doctors said her unborn child would be born 'severely disabled'. They said her son had spina bifida, and would never walk, talk or go to the toilet himself. They advised she could choose to terminate the pregnancy, but she was so desperate to be a mother she refused the procedure - and says it's the best decision she has ever made. Ciaran, now three, was born with no health problems (pictured inset) and is developing like any other toddler. He has learned to walk and is potty trained (he is pictured playing with his mother, left). Miss Rogers said she wants Glasgow Royal Infirmary to apologise. She said: 'He is a real miracle and I am furious at the doctors who told me to get rid of him.'

Jake Barrett (left), from Rushton, Northamptonshire, was left with a grape-sized sac of peroxide bleach under his tongue after he suffered a rare reaction to the Crest 1hr Express Strips (inset, top). It was 48 hours after he applied the £65 treatment that a painful cyst full of poison started to develop under his tongue, which could have burst at any moment and burned down to his stomach. He had to undergo an emergency three hour operation to drain the sac with a tube inserted through an incision under his chin, leaving him with a gaping hole (right). He was determined to get a Hollywood smile like his favourite actor, Channing Tatum (inset, bottom) and has since had laser teeth whitening surgery.

For years she has endured cruel taunts from bullies. Standing at just under 4ft 5ins Sanika Hussain, from Bradford, was labelled a 'freak'. But it wasn't until she reached 19 that doctors diagnosed her with a form of dwarfism - hypochondroplasia. Desperate to be like her peers, she put herself through five years of agonising medical procedures (right) to add three-and-a-half inches to her height. Both her legs were broken, metal rods inserted, and braces fixed to stretch her legs. She was forced to lie on her back for three years, while her bones recovered. Now measuring 4ft 8ins (left), Miss Hussain, said: 'I finally feel comfortable in my own skin. Although three-and-a-half inches may not sound like much, for me it was the difference between standing out and fitting in - between hating myself and feeling confident.'

Louise Peacock, 35, from Swansea, was diagnosed with ovarian cancer at 20, reducing her chances of conceiving naturally. After a long-term relationship broke down, she feared she would never have children. When doctors warned her that her 'biological clock was ticking quicker than other women' she decided to take action. She used a Canadian sperm donor and underwent IVF treatment (pictured left). She gave birth to twin boys Albie and Freddie on October 12, 2013 (they are pictured, right). The 35-year-old said she wants to share her story to inspire other single women not to give up on motherhood simply because they are not in a relationship. Miss Peacock said: 'You don't have to give up if you want a family - you don't have to have a partner there. And you can do it on your own. Just because you're not with someone who can give you children you don't have to give up on having a children.'

Sarah Wells, 38, from Hillingdon, London, was diagnosed with Ehler Danlos Syndrome (EDS) two years ago - after dislocating her joints hundreds of times doing normal and menial tasks. EDS means that the the connective tissue in her body, which support the skin, tendons, ligaments, blood vessels, organs and bones is weaker than usual, meaning her bones can dislocate dozens of times a week. She has dislocated her knee joint walking into a nightclub and cannot write a letter without her wrist joint popping out. Now, she believes her children Alfie, 11, Charlie, 8, and Rubie, 5, (all three pictured, inset, with Rubie pictured left and Charlie pictured right) are also suffering from the condition. They are all hypermobile and can bend their bodies into eye-watering positions. Mrs Wells hopes she can help her children as much as possible as the condition progresses. 'The doctors made me feel like I was making it up and I want it to be different for my children,' she said. 'I know that I have to help my kids so every day we have a family physiotherapy session where we'll stretch and do exercises that will help their bodies.'

Henry Hargreaves, a food photographer and artist based in Brooklyn, created a visual, candy representation of the amount of sugar found in some of your favorite sweetened beverages. To create the lollipops, he boiled each liquid on the stove top until the water was evaporated and the drinks were reduced to syrupy substances. Henry then poured the liquid into corresponding molds and added lollipop sticks to them.

Whitney Weldon, 23, of New Jersey, was diagnosed with fibrodysplasia ossificans progressive (FOP) when she was nine, one of the rarest and most disabling medical conditions. The disorder causes muscles, tendons, ligaments and other connective tissues in the body to turn into bone. Even the slightest knock can accelerate the growth of new bone, and freeze her into place like a statue. Over the years her condition has got progressively worse (she is pictured, right, with her brother Will, while she was still able to stand), and she now has limited movement in her arms, legs and head. She uses a wheelchair (pictured left) and has a full time carer who helps her cook, get dressed and bathe. And while she is likely to get worse as she ages, she hopes there will be advancements in medicine that can help her. She said: 'I don't think about the idea that one day I could be a statue. I just stay positive and live my life'

Mohammad Kaleem, who lives with his parents in a small village in Jharkhand State, eastern India, was born with the condition which saw his hands and arms grow until they weighed a colossal two stone between them. As a result of his illness, The family has suffered the wrath of superstitious neighbours in their remote village, who believed Kaleem's large hands to be the result of a curse, branding him a 'devil's child', and he was even refused admission to the local school because his hands would 'scare' other children. Now, Kaleem can look forward to a brighter future after undergoing surgery to 'shrink' his hands.

Lonan O'Herlihy, 26, from South Kensington, appeared in season eight of the show and has trained many of the cast members (he is pictured, left, with his co-star and housemate Binky Felstead). He says diet is more important than exercise in achieving a Chelsea-worthy body - and advises eating plenty of fruit, vegetables, lean meats and fish and avoiding red meat and dessert. Instead of drinking calorific cocktails, he ecommends opting for clear spirits like gin and vodka. And working out with friends can make exercise fun. When asked who he thinks is the fittest member of Made In Chelsea, he chuckles. 'Apart from me?,' he retorts, before naming most of the girls in the show.