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Charlize Theron lends her star power at Clinton Global Initiative health panel... as ex Sean Penn mingles with Bill and Chelsea

Published: 20:49 EST, 27 September 2015 | Updated: 07:13 EST, 28 September 2015

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Charlize Theron brought Hollywood glamour on Sunday to the Clinton Global Initiative in New York City.

The 40-year-old actress wore a chic black ensemble while addressing the annual summit organized by former US President Bill Clinton.

The South African-born beauty was taking part in a panel titled Investing in Prevention and Resilient Health Systems.

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Star power: Charlize Theron attended the Clinton Global Initiative on Sunday in New York City

Charlize wore a black blouse with white polka dots, a short black jacket and black capri skinny trousers while participating in a panel discussion.

She polished off her outfit with black Louboutin stiletto heels.

'Together, we can actually be the generation that stops AIDS,' Charlize said during the panel discussion.

Public health: The Oscar-winning actress spoke about ending the AIDS epidemic

Fan favourite: Charlize waved as she took the stage

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Actress Charlize Theron attended the Clinton Global Initiative in New York City to be a part of the Prevention and Resilient Health Systems panel.

The 40-year-old looked like she was ready to get down to business in her black blazer, polka dot button up, crop trousers and patent black pumps.

We are loving how Charlize added a playful touch to her professional attire with her Saint Laurent polka dot print shirt.

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Panel discussion: The actress took part in a panel discussion at the event

Annual event: Charlize was one of several celebrities taking part in the Clinton Global Initiative

Good point: The actress said this could be the generation that ends AIDS

Taking a break: Charlize took a sip during the panel

The actress founded the Charlize Theron Africa Outreach Project in 2007 to support African youth in the battle against HIV/AIDS.

In 2008 the Oscar-winning actress was also named a United Nations Messenger Of Peace.

She also made an appearance on Sunday at the United Nations for a panel on Ending the AIDS epidemic by 2030.

On the stage:Michel Lies, Group CEO of Swiss Reinsurance Company, shared the stage with Charlize

Mother of two: The actress recently adopted her second child

Polite applause: Charlize clapped during the panel discussion

'We know what works. Empowering young people to take care of their health,' Charlize said.

Meanwhile, Charlize's ex boyfriend Sean Penn was seen in the audience during the evening's awards show.

The 55-year-old actor was pictured in the audience at the Clinton Citizen Awards event sitting next to Chelsea Clinton and also shook hands with the former US president himself.