Mary and Brad Grier from Madison, Alabama, were told at 20 weeks their unborn babies were suffering twin-to-twin transfusion syndrome - where their sons shared a placenta. At 20 weeks baby Greyson passed away in the womb, and three weeks later after Mary's waters broke, the twin boys were delivered by emergency C-section. Jack was rushed to intensive care while his parents spent precious time with his brother Greyson. Doctors warned the couple Jack had only a 50/50 chance of surviving. But after 111 days in hospital he was deemed strong enough to go home. To mark his first birthday - a milestone they never thought they would reach - Mary and Brad compiled a video of his fight for life, to offer hope to other parents facing the same battle with their premature babies. Mary said: 'When Jack was born, I honestly thought I would walk out of that hospital empty handed with a broken heart that could never be mended... he's our happy ending.'

Christine Johnson, 28, of Moore, Oklahoma, was a 'chubby' child and weighed 15st 7lbs (98kg) by the time she was 17. At 20, she vowed to lose weight and began eating 'clean' or unprocessed foods and going to the gym (she is pictured, left, before her weight loss). Soon, she was exercising three times a day. For an entire year ate only vegetables. By the time she was 24, she had lost seven stone (44kg) (pictured right). For two years, she missed Christmas and birthday parties as she was busy exercising, or would worry they would serve unhealthy food. She even almost chose not to go and see her grandfather before he was having life-saving surgery because she wanted to continue working out. Finally, she realised she had a problem and a counsellor helped her overcome it.

WARNING: Story contains images some readers may find emotionally distressing. Natalie Morgan, 29, of Florida, is seen cuddling her dead daughter, Eleanor, in a series of Facebook pictures as she pleads with parents to be grateful for their children and remember her story. She says that she and her husband, Brian, spent six hours in the hospital with the child, who died in utero at 40 weeks.

Jewel Shuping, from North Carolina, had thoughts of being blind from a young age (left and inset). The 30-year-old was diagnosed with Body Integrity Identity Disorder, where able-bodied people believe they are meant to be disabled. She fulfilled her wishes when she arranged for a sympathetic psychologist pour drain cleaner into her eyes. Medics battled to save her eyes - against her wishes - but the corrosive substance melted her eyes and within six months she was blind (right). She said she can understand why people might be angry about someone giving themselves a disability but says it wasn't a choice but a need, based on a disorder of the brain.

Simone Anderson Pretscherer, 24, from Auckland, New Zealand, lost 189lbs in just 11 months, going from 372lbs to 183lbs. Some online critics who watched her progress on Facebook accused her of faking her weight loss because they couldn't see excess skin - but she had just hidden it in the pictures she'd posted. So the make-up artist silenced them by putting her skin on full display, and was met with a ton of support. Recently, however, she underwent a nine-hour surgery to get the skin removed because it had become cumbersome. She debuted her new figure on Tyra's new daytime show, FABLife and also shared photos of herself in belly-baring work-out clothes online.

Charlotte Fairlie, 34, from Monmouth, suffered a stroke caused by pre-eclampsia that has also left her partially paralysed. Now her husband Rob, 40, hopes to raise £40,000 through crowdfunding to help her recover. Charlotte's condition is improving although her speech remains limited and she requires round-the-clock care. Rob said: 'We're not out of the woods and we don't know what will happen but I just want us to be a normal family.'

The sight of Amal Clooney's (top left) gnarled feet will have had us mere mortals flinching in sympathy but she is not the only celebrity afflicted by bunions. David Bowie's wife Iman (top right), supermodel Naomi Campbell (bottom right) and even Victoria Beckham (bottom left) have been struck down by the unsightly deformity. So what are these unsightly podiatric protrusions - and how can you get rid of them?

WARNING GRAPHIC CONTENT: Bree Towner, 28, from Edwardsville, Illinois, developed a spot on her nose in January 2013, which failed to heal (pictured left). Two years later, it had grown to the size of a 'pencil eraser'. She was diagnosed with basal cell carcinoma, a growth in the skin's basal cells, which line the deepest layer of the epidermis (the skin's outer layer). She had surgery to remove the growth, and then operations to reconstruct her nose. But this involved taking skin from her scalp (pictured centre) and having to shave her nose. Both this and the horrific scars left her on the brink of suicide. Now, though she is cancer-free (pictured right), she has been warned there is a 40 per cent chance the disease will return. She wishes she could be 'scar-free', she said. She added: 'It's awesome that I'm cancer free, but I wish it wasn't such a visible consequence. I am now dating a guy that I knew before my surgeries and he makes me feel beautiful, so I am slowly healing in that respect, I guess.'

Louise Brent, 58, from Hull, East Yorkshire, suffers from a life-threatening illness that has almost killed her twice. She has already had half her face removed and paid more than £100,000 for treatment, which is only available overseas. Although Mrs Brent previously used her husband's redundancy money to pay for her medical bills, the couple can no longer afford the surgery she urgently needs. Now she may have to sell her house to fund further surgery to save her sight.

The baby boy, who has been named Angelito - meaning little angel or cherub -  was born at the hospital of Caleta, in the city of Chimbote, in the west Peruvian province of Santa. The boy's mother Lorena Rodriguez Zavaleta, 20, and his unnamed father, are constantly at their newborn's bedside.

Vicky, 49, from Hale, Manchester, who attended Altrincham Grammar School, started smoking cannabis when she was 11 years old and her life spiralled after that. Vicky, left, at school aged 15, and, right, at the height of her addiction aged 25, comes from a wealthy background and was expected to go into medicine or dentistry. However, her parents split when she was young and she hasn't seen her biological father since she was seven years old. The breakdown of the family unit, she explains, led her to feel as though there was a deficit in her life. She has now turned her life around and works as an addiction therapist, inset.

Tests on 274 sugar-sweetened soft drinks found some had more than double the sugar content of their equivalents in other countries. Sprite in Thailand had the most sugar per 330ml can with 12 teaspoons, while the same drink was found to have 5 teaspoons in countries including the Netherlands and France. Schweppes Tonic Water had the widest variation with seven teaspoons' difference between the U.S. and UK. Campaign group Action for Sugar, behind the research, has called for big brands to cut use of sugar in soft drinks.

EXCLUSIVE: Jack Wells, 23, from London, was diagnosed with Ewing's sarcoma, a rare form of bone cancer normally seen in children, which is now incurable as it has spread to his lungs, spine and arm. He began developing pain in his right shoulder when he was 21. He went to the doctor five times, but was told he probably had a pulled muscle or a trapped nerve. Then, in January, his mother noticed he had a huge lump in his shoulder, and doctors discovered he had cancer. He is undergoing chemotherapy to prolong his life, but has been told his cancer is incurable. He is now creating a memory book for daughter Scarlett, two, (pictured left, inset and right) including photographs and letters, to remember him by (he is pictured, left and right, with his daughter). Mr Wells said: He said: 'It's a black and gold book with plain black pages. I'll buy things from our days our and stick them in, and it'll be photos and cards and things. I want my little girl to have something to keep and see how much I love her. I think it would be the perfect way to keep memories of us together close to her.'

Dr Kimber Stanhope from University of California Davis, top right, explains how fructose, often found in fizzy drinks, is stored in the liver as fat, increasing the risk of heart disease, stroke and diabetes. Meanwhile glucose, commonly found in all grains referred to as carbs, are broken down in the intestines before travelling to the liver. There, the liver takes as much as it needs for energy, and the rest is then transported to other parts of the body in need of a boost.

Tom Attwater, 32, put aside his own health problems to raise money for future treatment his daughter Kelli (pictured left and above right) may need that is not available on the NHS. Mr Attwater walked Kelli, six, down the aisle at his wedding to her mother as he knew he wouldn't be there for hers in the future (main picture). She wrote a heartbreaking note saying he was 'the best dad in the world' (bottom right). He died, with wife Joely (top right) at his home in Staffordshire on Tuesday.

Zoubair Lahdodi, 18, from Casablanca, Morocco, has flown thousands of miles to New York for life-saving surgery to try and remove the growth, the result of a malformation of the veins in his face. The teenager was so popular for his amazing tricks on the streets of Casablanca, that he earned the nickname Stunteur Zoubair. But, the 18-year-old had no idea of how dangerous it could be if he fell from his bike. His surgeon Dr Milton Waner, at Lenox Hill Hospital, said: When I saw the video of him stunt cycling, I was absolutely horrified because any bump could result in a terminal haemorrhage. He could be very quickly overwhelmed and drown in his own blood. He has a high risk for bleeding, he has a high risk for spontaneous haemorrhage without me even touching him, so Zoubair is, I have to say, a walking time bomb, so we really have to get on and do his treatment.'

Surgeons are to be allowed to perform life-changing womb transplants in the UK for the first time, potentially allowing thousands of women to become mothers. The first UK baby born as a result of the pioneering transplant could arrive in 2017 and womb transplants are likely to be made widely available to childless women shortly afterwards. The women, to be chosen in the next three to four months, will be between 24 and 38, healthy and in long-term relationships. All will still have ovaries and some will have eggs of their own. Each new womb will come from a donor left brain dead by a car crash, heart defect or other illness. It will be removed in a three-hour operation before being transplanted in a six-hour procedure. It will then be allowed to 'bed in' for a year before IVF is carried out. If the woman becomes pregnant, the baby will be delivered by Caesarean section (explained in graphic, right). Sophie Lewis, 30 (left), who is in line to be one of the first Britons to receive the pioneering transplant, said it would be 'an amazing gift'.

Channel 5's Body Donors shows terminally ill Mike Bowyer, 77, of Bangor, North Wales, giving his last interview before he dies (he is pictured with four of his six children, right). 'You've only got one ride, and when the switch goes off, you better have a smile on your face,' he said. Next, the stomach-churning documentary shows his body being embalmed and then dissected by medical students (pictured centre). The show also follows the story of Diana King, 54, from Blackburn, who has incurable cancer (pictured left on her wedding day). After her death, her body is sent to train surgeons. She said: 'If it could help one more person after my death have a better or a longer life, then I get a bit of satisfaction out of that.'