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Updated: 05:56 EST

Manchester United vs Manchester City combined XI: Wayne Rooney misses out

JACK GAUGHAN: Manchester United welcome arch rivals City to Old Trafford for the crunch Premier League derby this Saturday. Not only will the highly-anticipated match see Pep Guardiola renew his rivalry with Jose Mourinho but the biggest stars in European football will take to the pitch. Here, Sportsmail lists a combined XI for Saturday lunchtime's crunch clash.

Manchester Uncovered: As United and City prepare to do battle... Sportsmail assesses what

SPECIAL REPORT: The most anticipated Manchester derby in recent times arrives on Saturday at 12.30pm at Old Trafford. It's not just a battle between two heavyweights in world football, it's also a clash of two of the most successful managers in modern history. Here, Sportsmail's CHRIS WHEELER, SIMON JONES, MIKE KEEGAN and JACK GAUGHAN assess just how much work Jose Mourinho and Pep Guardiola have done to so far to reshape Manchester United and Manchester City. 

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EXCLUSIVE BY SAMI MOKBEL: The Blues have begun an intensive scouting drive to unearth the best homegrown central defensive talent as Conte plans for the future.

Neymar came close to joining Manchester United and Paris Saint-Germain this summer, before committing his future to Barcelona, according to the Brazil star's agent Wagner Ribeiro.

Wilshere joined Bournemouth in a season-long loan deal on transfer deadline day, sparking suggestions his time at the Gunners could be up. But Wenger says the truth is the exact opposite.

CHRIS WHEELER: Mourinho and Pep Guardiola go head to head for the first time in English football, with United striker Ibrahimovic coming up against his former Barcelona boss.

Manchester United have won their opening three games of the Premier League season, and Cole believes United are on the way up under the management of Jose Mourinho.

Wenger, who intends to record the game and watch it after his Arsenal side play Southampton, feels the encounter between two of the league's biggest clubs has psychological importance.

As Jose Mourinho and Pep Guardiola prepare to go head-to-head for the first time in English football this weekend, one man has given a unique insight into the characters of the two famous managers.

Liverpool FC train in front of the new Anfield main stand

Anfield's new main stand takes the ground's capacity to 54,742, an increase of more than 8,000 seats, with the squad getting used to their new surrounding in training on Thursday. While the players got down to work, manager Jurgen Klopp was keen to have a look around as he inspected his new viewing point in the revamped dugout.

Real Madrid star Cristiano Ronaldo has announces 'I will play' against Osasuna

The 31-year-old forward sustained a knee injury in the European Championship final in July and has not played any football since. The Portuguese has been active on social media over the last week with updates on his intensified training regime and is now confident of taking some part in the game against Osasuna on Saturday. Earlier this week he told Real fans to 'enjoy the picture', as he trained with his team-mates for the first time since suffering the injury.

United vs City kicks off another action-packed weekend and you can find out the best bets by clicking here. We've got a selection for the big match plus a 100/1 Premier League shot.

Marouane Fellaini has played every minute of Manchester United's Premier League season so far, despite many claiming he was heading for the exit door under Jose Mourinho.

Alan Pardew has revealed Jonathan Benteke is in contention to make his Crystal Palace debut on Saturday when they travel to face Premier League newcomers Middlesbrough.

There is a buzz about the place again, a buoyancy ahead of tomorrow's seismic derby at Old Trafford.
It has not been felt since Sir Alex Ferguson left three years ago.

Down the road from Jose Mourinho's hotel base in Manchester, Pep Guardiola will wake up in his luxury apartment on Friday and go through his final preparations.

Real Madrid's 50 greatest players... Sportsmail picks the best to have worn the famous

There are few clubs in world football that inspire the same awe as Real Madrid, a side that established their dominance over world football early on and never looked back.  Last week we looked at the greatest players to play for Real's fierce rivals Barcelona, but who features in the top 50 players to pull on the gleaming white shirt of Real?

Even a blindfold can't stop Messi! Barcelona stars take on Spain's blind football team in heartwarming video

Lionel Messi and his Barcelona colleagues linked up with the Spanish national 5-a-side blind football team for a kickabout and penalty shootout contest... and unsurprisingly the Argentine maestro excelled. The Blaugrana players involved were given blindfolds and shown the tricks of the trade by their counterparts, who taught them how to connect with the ball, which makes a noise, via a device, when struck. When the spot-kicks came around, Barcelona and their opponents drew, with one penalty scored by each side from their three taken.

MIKE KEEGAN: Sportsmail understands officers would prefer to allow City's 3,000 travelling support to leave their rivals' stadium at the final whistle, along with United fans.

LIVERPOOL, ENGLAND - SEPTEMBER 06:  (THE SUN OUT, THE SUN ON SUNDAY OUT) Jurgen Klopp manager of Liverpool talks with Jordan Henderson during a training session at Melwood Training Ground on September 6, 2016 in Liverpool, England.  (Photo by Andrew Powell/Liverpool FC via Getty Images)

DOMINIC KING: First came the heel problem that left him feeling like he was walking on drawing pins. Then came the crack in one of his metatarsals before, finally, his medial ligament was torn.

Click on your team's name in the fixture list to discover who is fit for action and who misses out... as well as all the key statistics surrounding your club's fixture as the Premier League returns.

Gennady Golovkin has been taking on grown men since he was eight...and beating them, Kell

JEFF POWELL: The baby-faced assassin called Gennady Golovkin smiles when he talks to all and sundry, smiles when he walks down the street, smiles most broadly of all when he goes about his knock-out business in the prize ring. The Kazakh with a punch like a mule-kick is at his happiest when flattening challengers for his world middleweight titles. That is a routine he expects to continue when Kell Brook, Sheffield's world welterweight champion, steps up to scratch in London's O2 Arena this Saturday night. Golovkin is a living, breathing conundrum, unfailingly courteous in conversation, unrelentingly deadly inside the ropes.

Mark Wahlberg hangs out with Tottenham Hotspur trio at White Hart Lane

The transfer window may be over but Tottenham Hotspur welcomed one final new face to the club this week... none other than Hollywood star Mark Wahlberg. The global icon took time out from his busy filming schedule to pay a visit to his favourite UK football club this week and later uploaded a snap to his 3.7 million Instagram followers. Spurs stars Dele Alli, Michel Vorm and club legend Ledley King were eager to pose for a picture with the king of the big screen.

Stretching back to February 18, 2013, 34-year-old Serena Williams has held the top spot for 186 consecutive weeks, a record shared with German tennis legend Steffi Graf.

Saturday's Manchester derby at Old Trafford is set to be the most expensive game in football history, with United and City boasting sides worth a combined total of more than £600million.

Amir Khan is targeting a rematch with WBA world light-welterweight champion Danny Garcia - rather than a fight with compatriot Kell Brook - when he makes his return to the ring.

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Lukaku runs away from the goal after scoring as goalkeeper Konstantinos Panagi looks on        

Jamie Murray and Bruno Soares through to US Open men's doubles final after upset victory

MIKE DICKSON IN NEW YORK: Jamie Murray had already managed to outstay his more illustrious brother at the US Open, and he extended his visit all the way to the last weekend. Murray and Brazilian Bruno Soares knocked out top seeded French team Pierre-Hugues Herbert and Nicolas Mahut 7-5 4-6 6-3 to make a second Grand Slam final this year.

Katie Swan knocked out of US Open girls' singles by Wimbledon champion Anastasia Potapova

STUART FRASER IN NEW YORK: Katie Swan received treatment for a shoulder injury which appeared to hamper her during her 6-4, 6-1 defeat in 70 minutes by top seed Anastasia Potapova. Conditions were brutal at Flushing Meadows on Thursday, with the extreme heat policy being implemented due to the high temperature and humidity on court.

MIKE DICKSON IN NEW YORK: As Stan Wawrinka closed in on victory in their US Open quarter final the emotion caused by the crowd chanting his name proved too much for Juan Martin del Potro.

MARTIN SAMUEL IN NEW YORK: It was one of those matches when Andy Murray seems at war with a hundred things beyond his control. The sun. The rain. The floodlights.

STUART FRASER IN NEW YORK: Moments before walking on the court, Kerber's rise to world No 1 had been confirmed after Serena Williams suffered a shock defeat by Karolina Pliskova.

Anfield picture special as Liverpool FC prepare to unveil new Main Stand

Anfield is a special stadium. It is renowned for its unique atmosphere and is home to the most famous single-tiered stand in the world, the Kop. Rebuilt and remodelled several times since it opened in 1884 to play host to city rivals Everton, on Saturday Anfield will hold its largest attendance since it was converted to all-seater in the early 1990s. The new Main Stand will take the capacity to more than 54,000 and fans will surely flock in to see Jurgen Klopp's brand of heavy metal football. As fans prepare to head through the gates named after the club's most famous managers, Bill Shankly and Bob Paisley, and into Anfield's future, Sportsmail takes a look back through the years at the famous stadium with a picture special.

Manchester City gear up for derby with United as Pep Guardiola prepares for Jose Mourinho

Less than forty-eight hours away from his biggest test yet as Manchester City boss, Pep Guardiola was busy putting his squad through their paces on the training ground. City travel to Old Trafford on Saturday lunchtime for the first Manchester derby of the season, where the Spaniard will be greeted by an old foe in the dugout.

David Luiz, Jack Wilshere, Claudio Bravo and the other stars preparing for EPL debuts

The hotly-anticipated Manchester derby on Saturday lunchtime will herald the Premier League's return from its international break - and supporters around the country can expect to see a host of new signings in action for their teams. Since the last round of fixtures a fortnight ago we have been treated to the frantic conclusion of a summer transfer window that saw English top-flight clubs shell out a combined sum in excess of £1billion.

The FIFA Appeal Committee confirmed that they have rejected the appeals submitted by the Spanish clubs, who will now not be able to buy any players in the next two transfer windows.

Matteo Darmian could be heading towards the Manchester United exit door with the defender and Jose Mourinho's relationship at a 'complete breakdown'.

Midfielder Landon Donovan is returning to the LA Galaxy, ending a 21-month retirement. Donovan will play alongside Steven Gerrard and Robbie Keane as LA Galaxy eye the MLS title.

Pulis ruled out walking away from the club but predicted a 'tough' period ahead and brought up the prospect of potentially being dismissed once the takeover by a Chinese consortium is complete.

Borussia Dortmund supporters' groups have joined forces to boycott their visit to Red Bull Leipzig on Saturday ‒ and will instead listen to the match on radio.

MATT LAWTON and MIKE KEEGAN: Roberto Martinez received an eye-watering one-off severance payment of more than £10million from Everton after being sacked as their manager in May.

David De Gea and Ander Herrera relax ahead of the Manchester Derby... before appearing to

Following their afternoon out in Altrincham, David De Gea and Ander Herrera headed home in a black Mercedes, appearing to drive the wrong way down a one-way street in the process. Both players are likely to be involved when the two Manchester clubs meet at Old Trafford, with De Gea an ever-present so far this season and Herrara playing a part in two of Mourinho's first three league games in charge.

Luis Suarez already has 88 goals and 43 assists for Barcelona in 99 games!

When Luis Suarez signed for Barcelona after four seasons with Liverpool, there was intrigue surrounding whether he could continue his impressive goalscoring record for one of the most exciting teams in world football.

Alan Shearer statue to be unveiled outside St James' Park with ex-chief Freddy Shepherd

CHARLES SALE: A statue of Newcastle's record goalscorer Alan Shearer will be unveiled on Monday with the entire £250,000 cost met by former club chairman Freddy Shepherd and his family. The five-metre bronze sculpture outside St James' Park was commissioned by Shepherd in 2007 when he was owner of Newcastle, to mark Shearer's great achievements following his playing retirement.  The project was mothballed after Mike Ashley bought the club.

Since moving to Arsenal from Barcelona for £31.7m, the forward has scored 43 goals and assisted 25 more in 96 appearances, establishing himself as a star at the Emirates.

Our scout is a top football expert who attends matches each week searching for the next star. He will bring you his verdict in Sportsmail. This week it's Everton midfielder Tom Davies.

Pep Guardiola was on the receiving end of a tirade from super-agent Mino Raiola. He said the Manchester City boss 'didn't have the balls to sit down and talk' and said his football was boring.

Midfielder Craig Disley will make the 600th league appearance of his career when he leads his Grimsby Town team-mates out at Luton on Saturday.

ENFIELD, ENGLAND - SEPTEMBER 08:  Harry Kane talks to manager Mauricio Pochettino and assistant Jesus Perez during the Tottenham Hotspur training session at Tottenham Hotspur training centre on September 8, 2016 in Enfield, England.  (Photo by Tottenham Hotspur FC/Tottenham Hotspur FC via Getty Images)

RIATH AL-SAMARRAI: Mauricio Pochettino believes there's something special about Tottenham than means players are choosing to join for reasons other than money

Southampton manager Claude Puel does not expect to have record-signing Sofiane Boufal available for at least another month as the attacking midfielder builds up his fitness.

Manny Pacquiao admits lure of 'continuing his journey' in boxing ultimately led to his

While Manny Pacquiao's political career became a priority after he announced his 'retirement' from the ring in April, he says the lure of continuing his journey in boxing ultimately led to his comeback. Seven months after defeating American Timothy Bradley in Las Vegas in his much trumpeted farewell to the sport, the Filipino southpaw will return to the same city in November to challenge World Boxing Organisation welterweight champion Jessie Vargas. Though Pacquiao is an eight-division world champion and one of the greatest boxers ever, the whole experience of preparing for that November 5 fight feels strange as he will be competing for the first time as an elected senator in his homeland.

Kell Brook vs Gennady Golovkin: How British boxers have fared when moving up divisions? 

Kell Brook will jump two weight classes to take on fearsome middleweight Gennady Golovkin in London this weekend. A welterweight world champion in his own right, Brook will scale some 13lb heavier at Friday's weigh-in than he did before his last contest. Here, Sportsmail looks at other British boxers who recently moved up in weight - no matter how little - and how they got on.

Conor McGregor reveals how he celebrated UFC win over Nate Diaz with pool party video

Anyone who watched Conor McGregor's epic battle with Nate Diaz at UFC 202 will concede that the Irishman deserves time to celebrate. Still showing signs of the fight by hobbling in on crutches, McGregor revelled in a pool party at Encore Beach Club in Las Vegas less than a day after going the distance in an epic five round battle against the American. McGregor was joined by girlfriend Dee Devlin and welcomed at the packed resort by a banner held up by a procession of glamorous women which read, 'champ'.

CHRIS FOY - WORLD OF RUGBY: Time for an important declaration; this will be a Lions zone for the next 10 months. The head coach has been unveiled. The fires have been lit.

PETER CARLINE: The 2016 NFL season begins as the old one ended, with the Carolina Panthers and the Denver Broncos staging a rematch of Super Bowl 50 at Mile High.

JEFF POWELL: Kell Brook has walked onto the first big punch from Team Golovkin, 48 hours before he challenges the Kazakh KO king for the world middleweight championship.

LAWRENCE BOOTH: Eoin Morgan said previous brushes with security situations had left him determined 'not to put myself in that situation again'.

In a re-run of last season's Super Bowl the defending champions got a reprieve when Panthers kicker Graham Gano missed a 50-yard field goal with four seconds remaining in the fourth quarter.

British swimmers joined the gold rush as Ollie Hynd and Bethany Firth both set world records to win on a phenomenal first evening in the Aquatics Centre.

Sportsmail's racing expert Robin Goodfellow gives his hottest selections ahead of Friday's meetings at Doncaster, Chester, Salisbury and Sandown.

Ian Mongan knows what it is like to be an underdog. He also knows what it is like to be the underdog who succeeds. Eighteen seasons of hard-slog as a jockey, a riding career of consistent

The Daily Mail Schools Trophy is entering its fourth season... who can stop Wellington

Rugby is on a high after the Great Britain Sevens team gained a silver medal in the Olympics. Now you can take inspiration from that success as the Daily Mail Schools Trophy enters its fourth season.  The big question is, who can stop Wellington College collecting their third title?

Olympic rugby sevens hero Dan Bibby will be returning home this season to support Kirkham in the Daily Mail Schools Trophy which starts this weekend.

Holidays in France, including trips to watch mighty Toulouse, gave schoolboy international Charlie Gowling the inspiration to pursue a full-time career in the Top 14.

Not long ago I was asked to speak to a 1st XV team before a big traditional match - but first I listened to the captain's talk. He ranted about how much he 'hated' this particular opposition.

John McEnroe and Jimmy Connors slam spate of retirements ruining US Open... Where did our

MIKE DICKSON IN NEW YORK: Jimmy Connors, that ultimate warrior of Flushing Meadows, could barely restrain himself when the latest injury blow hit the US Open on Tuesday night. Jo-Wilfried Tsonga pulled out of his quarter-final with Novak Djokovic, meaning the Serb went through to the last four having played for a mere six hours and 26 minutes. That is what happens when you get two retirements in your matches and one walkover. The cumulative effect of that and other withdrawals was certainly testing the patience of Connors.

When Paul Gasgoigne signed for Lazio, Serie A was opened up to a new generation of fans. We remember the iconic players, characters and teams from a golden age of Italian football.

With the Premier League resuming after the international break, Sportsmail  columnist MARTIN KEOWN has been answering your questions on this weekend's games.

Liverpool and their charismatic boss, the England management, foreign adoptions and the same old issues with Rangers and Celtic. All wrapped up for you in this week's FIVE POINTS.