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  • image 29 Dec 2016 Review

    Targeting Toll-like receptors against cancer

    Bing Du , Qiu-Li Jiang , Joseph Cleveland , Bing-Rong Liu , Dekai Zhang

    The discovery of Toll-like receptors (TLRs) about 20 years ago was a remarkable achievement not only in the field of immunology but also in the field of medicine. The TLRs are a family of pattern recognition receptors which play an important role in immune responses by recognizing...

    Journal of Cancer Metastasis and Treatment [HTML] [PDF]
  • image 26 Dec 2016 Topic: Infectious Disease of Central Nervous System

    Screening of genetic loci predisposing to herpes simplex virus infection on mouse chromosome 17

    Xiu-Ying Chen , Wei-Ju Tang , Xu-Zheng Zuo , Gong Wang , Hao-Xiang Wang , Peng Xie , Wen Huang

    Aim: The herpes simplex virus (HSV), one of the most common viruses infecting humans, is featured by a high infection rate and usually causes complex disorders difficult to diagnose and treat. Disease progression is always combined with the specific interaction between organism and environment,...

    Neuroimmunology and Neuroinflammation [HTML] [PDF]
  • image 23 Dec 2016 Review

    Novel predictive and prognostic strategies of hepatitis B virus related hepatocellular carcinoma

    Wen-Bin Liu , Fan Yang , Ding-Yi Shao , Guang-Wen Cao

    Hepatocellular carcinoma (HCC) is a common malignancy and an important cause of cancer death worldwide. Chronic hepatitis B virus (HBV) infection is the major cause of HCC. Recent studies of HBV-induced carcinogenesis not only discovered many new biomarkers but also developed a novel theory:...

    Hepatoma Research [HTML] [PDF]
  • image 23 Dec 2016 Original Article

    Improvements in the cervical angle and anthropometric distances using elasticum suspension

    Seong Kee Kim , Kun Hwang , Hun Kim , Young Rok Kim , Yeop Na

    Aim: This study aims to characterize the effects of elastic facelifts using the elasticum suspension technique on the cervical angle and anthropometric distances. Methods: Forty-six patients underwent surgery. Two 4-5 mm incisions a few centimetres apart were made at sideburn. Through blunt...

    Plastic and Aesthetic Research [HTML] [PDF]
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  • image 12816 Topic: Biomaterials for Plastic and Aesthetic Surgery

    Intradermal fillers for minimally invasive treatment of facial aging

    Zhi Yuan (William) Lin , Vishva Shah , Arvind Dhinakar , Lara Yildirimer , Wen-Guo Cui , Xin Zhao

    The ever-increasing interest in retaining a youthful physical appearance has facilitated the development of various minimally invasive dermatological techniques. The use of intradermal fillers can be incorporated into dermatological practices with minimal overhead costs. This strategy addresses...

    Plastic and Aesthetic Research [HTML] [PDF]
  • image 5431 Topic: Brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations

    Tailored nanocarriers and bioconjugates for combating glioblastoma and other brain tumors

    Fatema ELAmrawy , Amr A. Othman , Chris Adkins , Aliaa Helmy , Mohamed I. Nounou

    Worldwide, the incidence of primary brain tumors is on the rise. Unfortunately, noninvasive drug therapy is hampered by poor access of most drugs to the brain due to the insurmountable blood-brain barrier (BBB). Nanotechnology holds great promise for noninvasive therapy of severe brain diseases....

    Journal of Cancer Metastasis and Treatment [HTML] [PDF]
  • image 5299 Review

    Neuronal toll-like receptors and neuro-immunity in Parkinson's disease, Alzheimer's disease and stroke

    Carmen D. Rietdijk , Richard J. A. van Wezel , Johan Garssen , Aletta D. Kraneveld

    Toll-like receptors (TLRs) are part of the innate immune system important for the initiation of proper immune responses towards microorganisms. Neuronal TLRs are considered to be part of the interactions between the immune system and the nervous system, the major sensing systems in mammals. The...

    Neuroimmunology and Neuroinflammation [HTML] [PDF]
  • image 4721 Review

    Hepatitis B virus molecular biology and pathogenesis

    R. Jason Lamontagne , Sumedha Bagga , Michael J. Bouchard

    As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular signaling processes. While beneficial for the viral replication cycle, virus-induced deregulation of host...

    Hepatoma Research [HTML] [PDF]
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