The Big Bang Theory promises exciting ends and new beginnings in hour-long two-part series finale

It's one of the most successful series on TV right now.

But fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday.

The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks.

End of an era: Fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday

End of an era: Fans of The Big Bang Theory will have to say goodbye to their beloved nerds when the show ends its 12-season run on CBS Thursday

Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project.

Then in The Stockholm Syndrome, the gang wraps things up as 'Bernadette and Wolowitz (Melissa Rauch and Simon Helberg) leave their kids for the first time.'

Meanwhile 'Penny (Kaley Cuoco) and Leonard (Johnny Galecki) try to keep a secret, Sheldon and Amy stick together and Koothrappali (Kunal Nayyar) makes a new friend, as the gang travels together into an uncharted future.'

The Big Bang Theory had been a hit since it first came onto the airwaves in 2007, earning blockbuster ratings, seven Emmy awards, and its own spin-off, Young Sheldon.

Laughs: The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks

Laughs: The one-hour double episode will follow the crew as they wait for big news, keep secrets and engage in their typical hijinks

Suspense: Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project

Suspense: Episode 278, The Change Constant, will follow Sheldon (Jim Parsons) and wife Amy (Mayim Bialik) as they 'await big news' about their Nobel Prize contending project

Talent: Above actors Kunal Nayyar, Simon Helberg, Joshua Malina and Johnny Galecki are seen from left to right

Talent: Above actors Kunal Nayyar, Simon Helberg, Joshua Malina and Johnny Galecki are seen from left to right

Parental supervision: In The Stockholm Syndrome, the gang wraps things up as 'Bernadette and Wolowitz (Melissa Rauch and Simon Helberg) leave their kids for the first time'

Parental supervision: In The Stockholm Syndrome, the gang wraps things up as 'Bernadette and Wolowitz (Melissa Rauch and Simon Helberg) leave their kids for the first time'

Lips are sealed: Penny (Kaley Cuoco) and Leonard (Johnny Galecki) try to keep a secret

Lips are sealed: Penny (Kaley Cuoco) and Leonard (Johnny Galecki) try to keep a secret

Buddied up: Koothrappali (Kunal Nayyar) makes a new friend

Buddied up: Koothrappali (Kunal Nayyar) makes a new friend

Success: The Big Bang Theory had been a hit since it first came onto the airwaves in 2007, earning blockbuster ratings, seven Emmy awards, and its own spin-off, Young Sheldon

Success: The Big Bang Theory had been a hit since it first came onto the airwaves in 2007, earning blockbuster ratings, seven Emmy awards, and its own spin-off, Young Sheldon

Saying farewell to her 'TV family' on Instagram, Kaley shared a photo of their 'last supper' together.

Mayim also marked the occasion on social media, posting a group photo with the caption: 'These kids.'

The core cast opened up about their experiences on the top-rated comedy, and about what they'll do next with the Associated Press while shooting their final show.

Kaley Cuoco explained: 'There's a lot of emotions going on, very bittersweet. It's very strange that a lot of people are coming up to me saying, "How are you?" like someone died.'

Last hurrah! Saying farewell to her 'TV family' on Instagram, Kaley shared a photo of their 'last supper' together

Last hurrah! Saying farewell to her 'TV family' on Instagram, Kaley shared a photo of their 'last supper' together

Gang's all here! Mayim also marked the occasion on social media, posting a group photo with the caption: 'These kids'

Gang's all here! Mayim also marked the occasion on social media, posting a group photo with the caption: 'These kids'

Parsons picked things up saying how the series finale is 'a real rite of passage moment in your life.'

'And much like more "normal rites of passage," be it a bar mitzvah or a wedding or a graduation, there is a feeling of accomplishment,' he continued. 'And like those events people also tend to cry, even if they are happy and they know that this was organic and the way life is supposed to go.'

Kaley had some ideas about how the show should wrap up, telling AP: 'It should just end with all of us around the table eating Chinese food, like we always do. Simple as that. 

Referencing one of the show's longstanding bits, she added: 'And I want them to fix the elevator. Or not fix it, but address it in some way.' 

The Big Bang Theory's two-part series finale airs Thursday, May 16 at 9pm EST. 

Going out with a bang! The Big Bang Theory's two-part series finale airs Thursday, May 16 at 9pm EST

Going out with a bang! The Big Bang Theory's two-part series finale airs Thursday, May 16 at 9pm EST

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The Big Bang Theory promises exciting ends and new beginnings in hour-long two-part series finale

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