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November 22, 2005
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Collection of Screening Specimens
  The specimens are samples of blood collected from infants by saturating marked areas of a filter paper card with blood obtained by skin puncture of the heel. In recognition of the role of Dr. Robert Guthrie in newborn screening, the specimen is now called the Guthrie spot. Each state has its own collection form on which some basic demographic information as well as the blood collection spots are recorded. Many factors determine the acceptability and quality of a specimen: the timing of collection, the provision of patient and specimen information, the collection of the blood specimen, and its subsequent handling. Problems with any of these may render a specimen invalid.  
Collection of Screening Specimens
  Timing of Specimen Collection
 
  Collection of Blood Specimen
 
  Specimen Handling
 
  Invalid Specimens
 
Newborn Screening
  March of Dimes Newborn Screening Recommendations
 
  Clinical Issues and Considerations
 
    - Introduction and History
 
    - Collection of Screening Specimens
 
    - Disorders: Description and Sample Screening Methodology
 
    - Results and Follow-up
 
    - Parent Education
 
    - Professional Education
 
    - Frequently Asked Questions
 
    - Glossary of Newborn Screening Acronyms and Abbreviations
 
  What Providers Can Do
 
  Resources for Families
 
    - March of Dimes Information for Families
 
    - Ask the March of Dimes Now
 
    - Other Resources
 
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