Naperville Gastroenterology

Stephen Holland, MD, FACP
1828 Bay Scott Circle - Suite 112
Naperville, IL  60540

Autoimmune Hepatitis Score Calculator

Patient: Male Female

AST or ALT = , AST or ALT ULN =
AP:transaminase ratio =

IgG level above normal: <1 x 1 - 1.5 x >1.5 - 2 x >2 x
ANA, SMA or LKM1: <1:40 1:40 1:80 >1:80
AMA: Positive Negative
Hepatitis Viral Markers: Positive Negative
Drug History: Present Absent
Average Daily Alcohol Intake: > 60 grams <25 grams
Histology: Interface hepatitis
Predominantly lymphoplasmacytic infiltrate
Rosetting of liver cells
None of the above
Biliary changes suggesting other specific disorder
Other feature suggestive of another disorder
Other Autoimmune Disease: Present Absent
Seropositive for other
defined antibodies:
Yes No (pANCA, anti-LC1, anti-SLA, anti-ASGPR, anti-LP, anti-sulfatide)
HLA DR3 or DR4: Present Absent
Response to Therapy: Complete Relapse after treatment

Autoimmune Hepatitis Score:

Pre-treatment: >15: Definite AIH; 10-15:Probable AIH
Post-treatment: >17: Definite AIH; 12-17 Probable AIH

This calculator is Copyright 2003, Stephen Holland, M.D.
Naperville Gastroenterology, Naperville, IL 60540
Permission is granted to use this calculator. Please eMail me to request permission for other use.
This calculator implements the scoring system described in International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol. 1999 Nov;31(5):929-38. That scoring system is somewhat complex in that some features contribute to the score only in the absence of other features. For example, HLA DR3 positivity only contributes when other antibodies are negative. This calculator correctly scores such circumstances. Also, it is not possible to check off boxes in an illogical fashion.
This calculator is kept at