The Broncos lost running backs P.J. Pope and Selvin Young to injuries during Sunday’s loss to the Bills, as both were placed on the injured reserve Monday to add to the plethora of Denver injuries at running back.

Giants coach Tom Coughlin refuted the idea his team has little to gain in the regular-season finale, but has yet to formulate a plan on how to approach the game in terms of resting starting players.

RB DeShawn Wynn will see carries behind RB Ryan Grant with Brandon Jackson out. CBs Charles Woodson and Al Harris are active and will start, as expected.

RB Matt Forte is active and will start, as expected. He’s safe to use in fantasy leagues. WR Marty Booker is also active.

Wade Phillips and the Cowboys have lingering injury concerns to several key players as they prepare for Sunday’s all-or-nothing matchup against the Eagles.

It’s no surprise given his performance the last several weeks, but Vikings QB Tarvaris Jackson will start the regular sesaon finale against the Giants.

With a team on the outside of the playoff picture and a quarterback within range of one of the NFL’s most exclusive records, it’s no surprise Saints coach Sean Payton spent most of his media session on Monday discussing how he will approach Sunday’s season finale against the Panthers.

With losses in four of the last five games, including two straight since clinching a playoff spot in Week 14, Cardinals coach Ken Whisenhunt believes his team is lacking confidence.

The Seahawks are out of the playoff hunt, but fans still packed the stands at Qwest Field Sunday. They braved blowing snow and freezing temperatures to say goodbye to Mike Holmgren, who coached his final home game.

At USC, Matt Leinart was the star quarterback, and Matt Cassel rode the pine as his backup. In the NFL, the roles are now reversed, as Cassel started for the Patriots in their 47-7 win over Arizona, where Leinart is backing up Kurt Warner. Cassel finished 20-of-36 for 345 yards and three touchdowns, while Leinart, who entered the game in the third quarter, fumbled the ball away and then threw an interception.

The struggling Cleveland Browns had been relegated to playing third-string QB Ken Dorsey. Now, they might be relegated to depending on those behind him to lead an offense that hasn’t scored a touchdown in five games.

About halfway through the fourth quarter of the Patriots’ 47-7 rout of the Arizona Cardinals, linebacker Junior Seau was taken to the ground by a fan who had jumped onto the field.

Thomas George reports from the Panthers-Giants game. Check back later for his complete column.

EAST RUTHERFORD, N.J. — If the Carolina Panthers and the New York Giants are, indeed, the two best teams in the NFC, both showed why Sunday night at Giants Stadium. And why this scrap likely was only a prelude.

With the AFC West title on the line next Sunday, the Week 17 Broncos-Chargers matchup has been moved to 8:15 p.m. ET and will air on NBC as part of flex scheduling.

Isaac Bruce and Jamal Lewis joined some exclusive company in Week 16, while Drew Brees put himself in position to challeng for one of the NFL’s most exclusive all-time records.

The NFC playoff picture became somewhat clearer on Sunday, as the Falcons’ 24-17 win over the Vikings assured them of a playoff spot.