Faculty » Keerti Rathore, Ph.D.

Keerti Rathore, Ph.D.

Principal Investigator, Laboratory for Crop Transformation

979-862-4795 | 116 Borlaug Center | rathore@tamu.edu

 

Education

  • Ph.D. D.I.C. Imperial College, University of London, U.K.
  • M.Sc. Gujarat University, India
  • B.Sc. Rajasthan University, India

Research Interests

Dr. Rathore's current research interests are in the genetic improvement of important dicot (cotton and soybean) and monocot (rice, sorghum, and maize) crops. Protocols for efficient delivery of genes, optimal expression of transgenes, and rapid recovery of transgenic cotton, rice, and sorghum plants have been established in my laboratory. These procedures are being used to conduct both basic and applied research pertaining to crop improvement. Projects include regeneration from cell & tissue cultures, use of new reporter and selectable marker genes to understand and improve the transformation process, promoter analysis, enhancement of disease resistance in plants, conferring draught tolerance to crop plants, conferring insect resistance to crop plants, improving nutritional quality of seeds, and production of recombinant antibodies and vaccines in plants.

Plant improvement through biotechnology depends greatly on our basic understanding of plant development. He is also interested in developmental physiology of higher plants, specifically in the possible role of ionic (Ca2+) gradients/currents in establishing and maintaining morphological polarity.

Recent Publications

  • PARKHI, V., KUMAR, V., CAMPBELL, L. M., Bell, A. A., Shah, j. & Rathore K. S. (2010) Resistance against various fungal pathogens and reniform nematode in transgenic cotton plants expressing Arabidopsis NPR1. Transgenic Research DOI 10.1007/s11248-010-9374-9.
  • DAMAJ, M. B., KUMPATLA, S. P., EMANI, C., BEREMAND, P. D., REDDY, A. S., RATHORE, K. S., BUENROSTRO-NAVA, M. T., CURTIS, I. S., THOMAS, T. L., MIRKOV, T. E. (2010) Sugarcane DIRIGENT and O-METHYLTRANSFERASE promoters confer stem-regulated gene expression in diverse monocots. Planta 231:1439-1458.
  • KUMAR, V., PARKHI, V., Kenerley, C. & Rathore K. S. (2009) Defense-related gene expression and enzyme activities in transgenic cotton plants expressing an endochitinase gene from Trichoderma virens in response to interaction with Rhizoctonia solani. Planta 230: 277-291.
  • PARKHI, V., KUMAR, V., Sunilkumar, g., CAMPBELL, L. M., SINGH, N. K. & Rathore K. S. (2009) Expression of apoplastically secreted tobacco osmotin in cotton confers drought tolerance. Molecular Breeding 23: 625-639.
  • Sunilkumar, g., Waghela, s. D., CAMPBELL, L. M. & Rathore K. S. (2009) Expresion of anti-K99 scFv in transgenic rice tissues and its functional characterization. Transgenic Research 18: 347-360.
  • Ren, s, mandadi, k. k., boedeker, a. l., Rathore K. S. & Mcknight, t. d. (2007) Regulation of telomerase in Arabidopsis by BT2, an apparent target of TELOMERASE ACTIVATOR1. Plant Cell 19: 23-31.
  • Sunilkumar, g., CAMPBELL, L. M., Puckhaber, L. & Rathore K. S. (2006) Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol. Proceedings of the National Academy of Sciences, USA 103: 18054-18059.
  • Burrell, A. M., Lineberger, R. D., Rathore K. S. & Byrne, D. H. (2006) Genetic variation in somatic embryogenesis of rose. Hortscience 41: 1165-1168.
  • Sunilkumar, g., CAMPBELL, L. M., Monjur, H. M., Connell J. P., Hernandez, E., Reddy A. S., Smith C. W. & Rathore K. S. (2005) A comprehensive study of the use of a homologous promoter in antisense cotton lines exhibiting high seed-oleic acid phenotype. Plant Biotechnology Journal 3: 319-330.
  • Jay, C. M., Bhaskaran, S., Rathore, K. S. and WAGHELA, S. D. (2004) Enterotoxigenic K99+ Escherichia coli attachment to host cell receptors inhibited by recombinant pili protein. Veterinary Microbiology 101: 153-160.
  • Emani, C., Garcia, J. M., Lopata-Finch, E., Pozo, M., Uribe, P., Kim, D-J., Sunilkumar, G., Cook, D. R., Kenerley, C. M. and Rathore, K. S. (2003) Enhanced fungal resistance in transgenic cotton expressing an endochitinase gene from Trichoderma virens. Plant Biotechnology Journal 1: 321-336.
  • Sunilkumar, G., Mohr, L., Lopata-Finch, E., Emani, C. and RATHORe, K. S. (2002) Developmental and tissue-specific expression of CaMV 35S promoter in cotton as revealed by GFP. Plant Molecular Biology 50: (3) 463-474.
  • Sunilkumar, g., Connell, J. P., Smith, C. W., Reddy, A. S., and Rathore, K. S. (2002) Isolation and functional characterization of alpha-globulin promoter from cotton in transgenic cotton, Arabidopsis and tobacco. Transgenic Research 11: 347-359.
  • EMANI, C., Sunilkumar, g. and RATHORE, K. S. (2002) Transgene silencing and reactivation in sorghum. Plant Science: 162:181-192.
  • Sunilkumar, G. and RATHORe, K. S. (2001) Transgenic cotton: factors influencing Agrobacterium-mediated transformation and regeneration. Molecular Breeding 8 (1): 37-52.

Invited Book Chapters

  • Rathore K. S. (2010)
    Cotton. In: Biotechnology in Agriculture and Forestry, Vol. 64: Genetic Modification of Plants, eds. F. Kempken and C. Jung (Springer-Verlag, Berlin Heidelberg, Germany), pp. 269- 285. DOI 10.1007/978-3-642-02391-0_15
  • Rathore K. S., Sunilkumar, G., Cantrell, R. G., hague, S. & reding H.K. (2008)
    Cotton. In: Compendium of Transgenic Crop Plants, Vol. 7: Transgenic Sugar, Tuber and Fiber Crops, eds. C. Kole and T. C. Hall (Wiley-Blackwell. Chichester, West Sussex, UK), pp. 199- 238.
  • Rathore K. S. (2008)
    Reducing Gossypol in Cottonseed may Improve Human Nutrition. In: Biotechnology: Perspectives & Prospects, eds. C. P. Malik, C. Wadhwani and B. Kaur (M.D. Publications, New Delhi), pp. 43-47.
  • Rathore K. S. (2007)
    Cotton. In: Biotechnology in Agriculture and Forestry, Vol. 61: Transgenic Crops VI, eds. E. C. Pua and M. R. Davey (Springer-Verlag, Berlin Heidelberg, Germany), pp. 107- 127.
  • RATHORE, K. S., Sunilkumar, G. & Campbell, L. M. (2006)
    Cotton (Gossypium hirsutum L.). In: Methods in Molecular Biology, Vol. 343: Agrobacterium Protocols, 2nd Ed., Vol 1, ed. K. Wang (Humana Press Inc. Totowa, NJ), pp. 267- 279.
  • RATHORE, K. S., SUNILKUMAR, G., PUCKHABER, L., STIPANOVIC, R. D., MONJUR, H. M., HERNANDEZ, E., and SMITH, C. W. (2003) Improvements in the nutritional quality of the cottonseed. Plant Biotechnology 2002 and Beyond. ed. I. K. Vasil (Kluwer Academic Publishers). pp. 417-420.

Patents

Awarded
  • Stem-regulated, plant defense promoter and uses thereof in tissue-specific expression in monocots (2007). M. B. Damaj, T. E. Mirkov, S. P. Kumpatla, A. S. Reddy, T. L. Thomas, K. S. Rathore and C. Emani. Patent No.: US 7,253,276.
  • Cotton alpha-globulin promoter for seed-specific expression of transgenes (2007). K. S. Rathore, G. Sunilkumar, J. P. Connell, A. S. Reddy. Patent No.: AU 2002/364158.
  • Stem-regulated, plant defense promoter and uses thereof in tissue-specific expression in monocots (2008) T. E. Mirkov, M. B. Damaj, A. S. Reddy, T. L. Thomas, K. S. Rathore and C. Emani, S. P. Kumpatla. Patent No.: US 7,323,622.
  • Cotton alpha-globulin promoter for seed-specific expression of transgenes (2009). K. S. Rathore, G. Sunilkumar, J. P. Connell, A. S. Reddy. Patent No.: US 7,626,081.
Pending
  • Cotton plant with seed-specific reduction in gossypol (2007). K. S. Rathore, G. Sunilkumar, L. M. Campbell. Published U.S. patent application # 20070199098.