Waste and Cleanup Risk Assessment
Databases and Tools
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Key Human Health Databases and Tools
- EPA Integrated Risk Information System (IRIS)
IRIS is a database of human health effects that may result from exposure to various substances found in the environment. - Integrated Exposure Uptake Biokinetic Model for
Lead in Children (IEUBK)
The Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) attempts to predict blood-lead concentrations (PbBs) for children exposed to lead in their environment. The model allows the user to input relevant absorption parameters (e.g., the fraction of lead absorbed from water) as well as intake and exposure rates. - Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead
in Children
(February 1994) [NTIS #PB93-963510, OSWER #9285.7-15-1]
Table of Contents and Glossary (PDF) (28 pp, 292K)
Chapter 1 (PDF) (29 pp, 230K)
Chapter 2 (PDF) (50 pp, 1.3MB)
Chapter 3 (PDF) (13 pp, 334K)
Chapter 4 (PDF) (67 pp, 578K)
Chapter 5 (PDF) (32 pp, 249K)
Chapter 6 (PDF) (11 pp, 94K)
Appendix A (PDF) (16 pp, 252K)
Appendix B (PDF) (5 pp, 38K)
- Recommendations of the Technical Review Workgroup for
Lead for an Approach to Assessing Risks Associated with Adult Exposures to Lead in Soil
(January 2003) [EPA-540-R-03-001, OSWER Dir #9285.7-54]
This document describes a methodology for assessing risks associated with non-residential adult exposures to lead in soil. The methodology focuses on estimating fetal blood lead concentration in women exposed to lead-contaminated soils. This approach also provides tools that can be used for evaluating risks of elevated blood lead concentrations among exposed adults. Based on the TRW's analysis of the data collected in the completed NHANES III survey (Phases 1 and 2), updated ranges for the baseline adult PbB and GSDi adult parameters in the EPA ALM have been included in the spreadsheets. Although the use of these updated ranges in the EPA ALM would not appreciably change PRGs calculated with the methodology, it is recommended that data from both phases of NHANES III be used in all PbB analyses; this is consistent with CDC recommendations. - Adult Lead Model spreadsheet (Lotus 123)
(37K)
Calculation of PRGs, Appendix B of Adult Lead Model Guidance [EPA-540-R-03-001, OSWER Dir #9285.7-54]
Adult Lead Model spreadsheet (MS Excel) (97K)
Calculation of PRGs, Appendix B of Adult Lead Model Guidance [EPA-540-R-03-001, OSWER Dir #9285.7-54]
Adult Lead Model Review Report (PDF) (82 pp, 1.7MB)
[EPA 9285.7-46] - Risk Assessment Guidance for Superfund, Volume I
Part D (1998) - Soil Screening Calculations for Chemicals
Soil Screening Guidance is a tool for screening at National Priorities List (NPL) sites. - Soil Screening Calculations for Radionuclides
Soil Screening Guidance is a tool for screening at National Priorities List (NPL) sites. - Johnson and Ettinger (1991) Model for Subsurface Vapor Intrusion into Buildings
A series of models for estimating indoor air concentrations and associated health risks from subsurface vapor intrusion into buildings. These models were based on the analytical solutions of Johnson and Ettinger (1991) for contaminant partitioning and subsurface vapor transport into buildings. - Vapor Intrusion Guidance (PDF)
(178 pp, 2MB)
A draft guidance that provides current technical and policy recommendations on determining if the vapor intrusion pathway poses an unacceptable risk to human health at cleanup sites
Key Ecological Databases and Tools
- ECOTOX Database System
The ECOTOX (ECOTOXicology) database provides single chemical toxicity information for aquatic and terrestrial life. ECOTOX is a useful tool for examining impacts of chemicals on the environment. - Ecological Soil Screening Levels (ECO-SSL)
- Ecotox Thresholds (1996)
EPA-developed software that calculates Ecotox Thresholds (ETs) for selected chemicals - Wildlife Exposure Factors Handbook (1993)
The Wildlife Exposure Factors Handbook provides data, references, and guidance for conducting exposure assessments for wildlife species exposed to toxic chemicals in their environment.