Our research exploits mouse genetics to investigate cell interactions underlying mammalian development and immune recognition. ES cell technology allows us to generate conditional mutations, knock-in alleles, perform cell marking experiments, and manipulate expression levels of key signalling molecules under physiological conditions in vivo.
Requirements for the molecular chaperones Ii chain and DM in guiding MHC class II antigen presentation
Click here for details of project available through 4 year DPhil Departmental Studentship Competition 2013
