How Pressure-Based Microplate Volume Measurement Works

By Knaide, T.

This article was originally published in Lab Manager. Problem: In virtually all research processes in which analytes and reagents are mixed in microplates, precise information on the starting volume in each plate well is critical to the accuracy and success of the process, as well as the results derived from it. While effective tools for […]

Best Practices for the Use of Micropipettes

By Carle, B., Rodrigues, G., Rumery, D.

This study evaluates a number of techniques that influence the accuracy and precision of the pipetted volume. The pipette operator has the ability to control all of these parameters by using the appropriate pipetting technique, as well as by choosing the appropriate pipette size and type of pipette tips.

Pressure-Based Volume Measurement Technology for In-Process Measurement of Microplate Contents

By Gigante, B., Schwedes, C. - STRATEC, Bradshaw, J. - Artel

Introduction Modern drug discovery and research labs are utilizing complex automation systems to assist in high throughput screening of novel drug candidates. A large portion of these laboratories are using ANSI-SBS-standard 96- and 384-well plates to achieve the necessary throughput. The volume of sample transferred into and out of these plates can be critical to […]

Environmental Studies Using the Tecan QC Kit and an Automated Liquid Handling System

By Rodrigues, G., Avis, E. - Artel, Price, A., Gerber, V. - Tecan

Liquid handler performance can be optimized by adjusting system operating parameters, but the effect of environmental conditions on liquid handling quality is often underappreciated.

Minimizing Liquid Delivery Risk: Automated Liquid Handlers as Sources of Error

By Albert, K.

To reduce liquid handling error, laboratories must implement regular calibration programs and verification checks for volume transfer accuracy and precision and to quickly identify those systems that are failing. The evaluation method should be standardized, fast, easy to implement, and minimize instrument downtime and required resources.