Amoxicillin and Clavulanate Potassium - Drug Information
Latest prescription information about Amoxicillin and Clavulanate Potassium. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Amoxicillin and Clavulanate Potassium
Pronunciation : (a mox i sill' in) (klav' yoo la nate)
Therapeutic Classification : Antibiotics
ICD Code : Y40.0
Pronunciation : (a mox i sill' in) (klav' yoo la nate)
Therapeutic Classification : Antibiotics
ICD Code : Y40.0
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India- Clavunate.
Why it is prescribed (Indications) :
This combination medication contains semisynthetic antibiotic amoxicillin and β-lactamase inhibitor, prescribed for lower respiratory infections, otitis media, sinusitis, urinary tract infections, and skin and skin Structure infections.
When it is not to be taken (Contraindications):
Contraindicated in patients with previous history of cholestatic jaundice/liver dysfunction, and hypersensitivity.
♦ Pregnancy Category : |
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Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Dosage & When it is to be taken :
Adults- The usual adult dose is one amoxicillin and clavulanate potassium tablet, 500 mg/125 mg every 12 hours or one amoxicillin and clavulanate potassium tablet, 250 mg/125 mg every 8 hours.
How it should be taken :
It comes as a tablet and capsule to take by mouth, with or without food.
Warnings and Precautions : Caution should be exercised in patients with history of liver or kidney disease, elderly, children, during pregnancy and breastfeeding.
Avoid long-term use of this medication; otherwise it may cause secondary infection.
♦ It may increase prothrombin time; monitor it regularly while taking this medication.
Side Effects : Gastrointestinal- Diarrhea, nausea, vomiting, indigestion, stomach inflammation, mouth ulcer and intestinal bleeding.
Hypersensitivity- Skin rashes, itching, hives, angioedema and serum sickness-like reactions.
Liver- Elevated liver enzyme levels.
Genitourinary- Kidney inflammation, and blood in urine.
Central Nervous System- Agitation, anxiety, behavioral changes, confusion, convulsion, dizziness, sleeplessness and reversible hyperactivity.
Other Precautions : Avoid excess dosage.
Storage Conditions : Store it at room temperature and in an airtight container. ♦ Safety Labeling Changes Approved By FDA
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