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Dr. Joseph E. Pizzorno N.D.

Persistent Organic Pollutants and Glutathione Depletion

Close to 60,000 chemicals are now in use in North America resulting in approximately 8 billion tons being released into the environment every year. Many of these organic compounds resist breakdown and thus accumulate in not only the environment, but plants, animals and humans as well. Hence the term, Persistent Organic Pollutants (POPs). Many, if not most, are metabolic poisons causing disruption of cell signaling, endocrine hormone dysregulation, disruption of insulin secretion and sensitivity, neurotoxicity—the list is long and growing as new research becomes available. This presentation briefly covers sources and then focuses primarily on metabolic disruption (both specific and total oxidative load) and clinical impact (ADHD, aging, cardiovascular disease, dementia, diabetes, thyroid disruption, etc.). Various strategies for assessment are also discussed. For intervention, special attention is places on the role of glutathione for neutralizing the toxicity of POPs and facilitating their excretion. Finally, the several ways to facilitate glutathione production will be critically assessed.

Dr. Joseph Pizzorno is one of the world’s leading authorities on science-based natural medicine, a term he coined in 1978. A physician, educator, researcher and expert spokesman, he is the founding president of Bastyr University, Editor-in-Chief of Integrative Medicine, A Clinician’s Journal, Vice-chair of the Board of Directors of the Institute for Functional Medicine, co-founder and Treasurer of the Board of Directors of the American Association of Naturopathic Physicians, and Chair of the Science Board of Bioclinic Naturals. He is recipient of numerous awards and honors, the most recent being Clinician of the Year (2012) by the Natural Products Associations. He is author or co-author of 8 books, including the widely acclaimed Textbook of Natural Medicine and best-selling Encyclopedia of Natural Medicine (new editions in 2012).