OCG Mission

The NCI’s Office of Cancer Genomics (OCG), within the Center for Cancer Genomics, aims to advance and accelerate genomics science and enhance the understanding of the molecular mechanisms of cancer. In fulfilling this mission, OCG programs generate data and resources, and develop tools that can be broadly used by the research community to efficiently improve cancer prevention, early detection, diagnosis, and treatment.

Learn more about OCG 

Current Programs

Cancer Genome Characterization Initiative banner shows logo, genomics cartoon, and a boy with his dad. Links to program landing page.

CGCI supports cutting-edge genomics research on adult and pediatric cancers. Researchers develop and apply advanced sequencing and other genome-based methods to identify novel genetic abnormalities in tumors. The extensive genetic profiles generated by CGCI may inform better cancer diagnosis and treatment.

CTD2 bridges the gap between the enormous volumes of data generated by genomic characterization studies and the ability to use these data for the development of human cancer therapeutics. It specializes in computational and functional genomics approaches critical for translating next-generation sequencing data, as well as high-...

Therapeutically Applicable Research to Generate Effective Treatments

TARGET applies a comprehensive genomic approach to determine molecular changes that drive childhood cancers. Investigators form a collaborative network to facilitate discovery of molecular targets and translate those findings into the clinic. TARGET is managed by NCI’s Office of Cancer Genomics and Cancer Therapy Evaluation Program.

Completed Programs

CGAP: Cancer Genome Anatomy Project
ICG: Initiative for Chemical Genetics
MGC: NIH Mammalian Gene Collection

Initiated Programs

CGEMS: Cancer Genetic Markers of Susceptibility
TCGA: The Cancer Genome Atlas