High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 25,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Wednesday, November 23rd, 2016
utilization graph
Last 24 hrs
165,537 jobs submitted
140,141 jobs completed
1,652,746 CPU hrs used
20 NIH Institutes
131 Principal Investigators
220 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Integrative network analysis reveals molecular mechanisms of blood pressure regulation
Tianxiao Huan, Qingying Meng et al.
Mol Syst Biol. , doi: 10.15252/msb.20145399 (2016)

thumbnail image from paper C. elegans DAF-2 as a Model for Human Insulin Receptoropathies
David A. Bulger, Tetsunari Fukushige, Sijung Yun, Robert K. Semple, John A. Hanover, and Michael W. Krause
Genes|Genomes|Genetics , doi:10.1534/g3.116.03718 (2016)

thumbnail image from paper Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors
Gerlinde Layh-Schmitt, Shajia Lum Fatemehm Navid, Stephen R. Brooks, Emily Lazowick, Kathryn M. Davis, Cristina Montagna, Massimo Gadina, Robert A. Colbert
Clinical Rheumatology , doi:10.1007/s10067-016-3469-5 (2016)

thumbnail image from paper Two Na + Sites Control Conformational Change in a Neurotransmitter Transporter Homolog
Sotiria Tavoulari, Eleonora Margheritis, Anu Nagarajan, David C. DeWitt, Yuan -Wei Zhang, Edwin Rosado, Silvia Ravera, Elizabeth Rhoades, Lucy R. Forrest and Gary Rudnick
J Biol Chem. , doi: 10.1074/jbc.M115.692012. (2016)

thumbnail image from paper Serine/Threonine Phosphatases and Aquaporin-2 Regulation in Renal Collecting Duct
Sophia LeMaire, Viswanathan Raghuram, Cameron R. Grady, Christina M. Pickering, Chung-Lin Chou, Ezigbobiara N Umejiego, Mark A. Knepper
Am. J. Physiol. - Renal Physiol. , DOI: 10.1152/ajprenal.00455.2016 (2016)

thumbnail image from paper Identification of a novel lipid binding motif in apolipoprotein B by the analysis of hydrophobic cluster domains
Scott M. Gordon, Mohsen Pourmousa, Maureen Sampson, Denis Sviridov, Rafique Islam, B. Scott Perrin Jr., Georgina Kemeh, Richard W. Pastor, Alan T. Remaley
Biochimica et Biophysica Acta - Membranes , doi://10.1016/j.bbamem.2016.10.019 (2016)

thumbnail image from paper Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association
Jan Domanski, George Hedger, Robert B. Best, Phillip James Stansfeld, and Mark S. P. Sansom
J. Phys. Chem. B , doi://10.1021/acs.jpcb.6b08445 (2016)