The Odom group is interested in understanding the molecular basis behind the regulatory evolution of tissues, species and cancer.  We typically begin our studies using liver and liver cancer as model systems.  Our interest in transcriptional regulation encompasses the roles of transcription factors, insulator elements such as CTCF, non-coding RNAs and repetitive elements.  We have been using Next Generation Sequencing (NGS) extensively in our past work and are now also incorporating CRISPR/Cas9 and single cell sequencing technologies into our ongoing projects.