How to Prepare for your Colonoscopy

On the day before your procedure…

  • You may have a light breakfast or have clear liquids ONLY; please have nothing for dinner.
  • DO NOT drink milk
  • DO NOT eat or drink anything colored red or purple
  • DO NOT drink alcoholic beverages

Any of the following liquids are OK to drink

Strained fruit juices (without pulp) including apple, orange, white grape, or white cranberry
Limeade or lemonade
Coffee or tea. DO NOT use any dairy or non-dairy creamer
Chicken broth
Gelatin desserts without added fruit or toppings (NO RED OR PURPLE)


SUPREP Bowel Prep Kit is taken as a split dose (2-day) regimen. You take the first 6-ounce bottle of SUPREP the evening before your colonoscopy and the second 6-ounce bottle of SUPREP the morning of your colonoscopy. It is important to drink the additional water as recommended in the Instructions for Use. Both 6-ounce bottles are required for a complete prep. Your doctor will tell you when it is time to begin to take each dose.


  • On the evening before your procedure (or when your doctor tells you to begin), complete steps 1 through 4 using one (1) 6-ounce bottle before going to bed
  • On the morning of your procedure, repeat steps 1 through 4 using the other
    6-ounce bottle

Both 6-ounce bottles are required for a complete preparation.


Step 1:
Pour ONE (1) 6-ounce bottle of SUPREP liquid into the mixing container.

Step 2:

Add cool drinking water to the 16-ounce line on the container and mix.

NOTE: Be sure to dilute SUPREP as shown at left before you drink it.

Step 3:
Drink ALL the liquid in the container.
Step 4:

You must drink two (2) more 16-ounce containers of water over the next 1 hour.

NOTE: You must finish drinking the final glass of water at least 2 hours, or as directed, before your procedure.

SUPREP ® Bowel Prep Kit (sodium sulfate, potassium sulfate and magnesium sulfate) Oral Solution is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults. Most common adverse reactions (>2%) are overall discomfort, abdominal distention, abdominal pain, nausea, vomiting and headache. Use is contraindicated in the following conditions: gastrointestinal (GI) obstruction, bowel perforation, toxic colitis and toxic megacolon, gastric retention, ileus, known allergies to components of the kit. Use caution when prescribing for patients with a history of seizures, arrhythmias, impaired gag reflex, regurgitation or aspiration, severe active ulcerative colitis, impaired renal function or patients taking medications that may affect renal function or electrolytes. Use can cause temporary elevations in uric acid. Uric acid fluctuations in patients with gout may precipitate an acute flare. Administration of osmotic laxative products may produce mucosal aphthous ulcerations, and there have been reports of more serious cases of ischemic colitis requiring hospitalization. Patients with impaired water handling who experience severe vomiting should be closely monitored including measurement of electrolytes. Advise all patients to hydrate adequately before, during, and after use. Each bottle must be diluted with water to a final volume of 16 ounces and ingestion of additional water as recommended is important to patient tolerance.

Click here for Full Prescribing Information and Medication Guide

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