9560/0 Psammomatous schwannoma
Related terms
Neurilemoma, NOSAcoustic neuroma
Pigmented schwannoma
Plexiform schwannoma
Cellular schwannoma
Degenerated schwannoma
Ancient schwannoma
Definitions
| Peripheral nerves and autonomic nervous system | ||
| ICD-O-3 topography code: | C47 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 1
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Tumours of the central nervous system | ||
| ICD-O-3 topography code: | C70, C71 and C72 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 3
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Stomach | ||
| ICD-O-3 topography code: | C16 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 5
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> st majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis OMIM or neurofibromatosis type II (NF2) OMIM , but not NF1.
Melanotic schwannoma>
| Hypopharynx, Larynx and Trachea | ||
| ICD-O-3 topography code: | C13, C32, C33 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 7
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Nasal cavity and Sinuses | ||
| ICD-O-3 topography code: | C30-C31 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 9
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> entional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Breast | ||
| ICD-O-3 topography code: | C50 | |
Schwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells.
Neurofibroma and schwannoma of the breast are discussed together under, Benign peripheral nerve-sheath tumours.
| Adrenal gland | ||
| ICD-O-3 topography code: | C74 | |
/span>i>Schwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 13
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Kidney | ||
| ICD-O-3 topography code: | C64 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 15
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Colon and rectum | ||
| ICD-O-3 topography code: | C18-C20 | |
Schwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 17
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Schwannoma of the colon and rectum
Schwannomas similar to those in the stomach occur in the colon and rectum, usually in older adults. Presentations include gastrointestinal bleeding and a polypoid, obstructing, intraluminal mass. The histological features of these tumours are similar to those in the stomach, with the typical features including peritumoral lymphoid cuff and microtrabecular architecture. Small mucosal nerve sheath tumours occur in the colon and rectum. The designation ?mucosal Schwann cell hamartoma? has also been used for apparently similar lesions. These tumours are clinically indolent and are not associated with neurofibromatosis type 1 (NF1) 18
| Click to access Pubmed |
Mucosal Schwann cell "hamartoma": clinicopathologic study of 26 neural colorectal polyps distinct from neurofibromas and mucosal neuromas.
Am J Surg Pathol 33: 781-7
| Click to access Pubmed |
Schwannomas in the colon and rectum: a clinicopathologic and immunohistochemical study of 20 cases.
Am J Surg Pathol 25: 846-55
WHO Classification of Tumours of the Digestive System.
4th Edition
International Agency for Research on Cancer: Lyon 2010
| Bone | ||
| ICD-O-3 topography code: | C40-C41 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 21
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>
| Connective, subcutaneous and other soft tissues | ||
| ICD-O-3 topography code: | C49 | |
/span>chwannoma is a benign nerve sheath tumour that is typically encapsulated and composed entirely of well-differentiated neoplastic Schwann cells. The vast majority of schwannomas follow a benign clinical course (WHO grade I) 23
WHO Classification of Tumours of the Central Nervous System.
4th Edition
International Agency for Research on Cancer: Lyon 2007
Histological variants:
> ntional or cellular type. The vast majority arise in skin or subcutaneous tissue of an extremity, head and neck, or trunk. Cranial and spinal nerves are usually spared. There is a low association with schwannomatosis and NF2 , but not NF1.
Melanotic schwannoma>