a–c, L655,708 treatment starting from 3-days post-stroke resulted in a dose-dependent improvement in functional recovery post-stroke. d–f, Gabra5−/− and Gabrd−/− mice also showed decreased motor deficits post-stroke. Functional recovery was assessed with forelimb (a, d) and hindlimb foot-faults (b, e), and on the forelimb asymmetry (c, f). Low-dose L655,708 = 200μg/kg/day per animal; high-dose L655,708 = 400μg/kg/day per animal. Data are ± s.e.m. *** = P≤0.001 stroke + vehicle vs Sham; + = P≤0.05, ## = P≤0.01, # = P≤0.001 vs stroke + vehicle.