UV damage, DNA repair and skin carcinogenesis.

@article{Cleaver2002UVDD,
  title={UV damage, DNA repair and skin carcinogenesis.},
  author={J. E. Cleaver and Eileen Crowley},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2002},
  volume={7},
  pages={
          d1024-43
        }
}
  • J. E. Cleaver, Eileen Crowley
  • Published in
    Frontiers in bioscience : a…
     2002
  • Biology, Medicine
    • Skin cancer is unique among human cancers in its etiology, accessibility and the volume of detailed knowledge now assembled concerning its molecular mechanisms of origin. The major carcinogenic agent for most skin cancers is well established as solar ultraviolet light. This is absorbed in DNA with the formation of UV-specific dipyrimidine photoproducts. These can be repaired by nucleotide excision repair or replicated by low fidelity class Y polymerases. Insufficient repair followed by errors… CONTINUE READING
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 200 REFERENCES

    Ultraviolet Radiation Carcinogenesis

    VIEW 5 EXCERPTS

    Trichothiodystrophy: update on the sulfur-deficient brittle hair syndromes.

    VIEW 19 EXCERPTS
    HIGHLY INFLUENTIAL

    Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.

    VIEW 6 EXCERPTS
    HIGHLY INFLUENTIAL

    Pigmentary and cutaneous risk factors for non-melanocytic skin cancer--a case-control study.

    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    Cerebro-oculo-facio-skeletal syndrome with a nucleotide excision-repair defect and a mutated XPD gene, with prenatal diagnosis in a triplet pregnancy.

    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells.

    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    Genetic epidemiology of cutaneous melanoma: a global perspective.

    VIEW 3 EXCERPTS
    HIGHLY INFLUENTIAL

    Sequential assembly of the nucleotide excision repair factors in vivo.

    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    Mapping of interaction domains between human repair proteins ERCC1 and XPF.

    VIEW 7 EXCERPTS
    HIGHLY INFLUENTIAL

    Mechanisms of DNA excision repair.

    VIEW 4 EXCERPTS
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