Binary Genetic Cassettes for Selecting XNA‐Templated DNA Synthesis In Vivo†
We thank G. Schepers for the synthesis of the oligonucleotides, Dr. J. Rozenski for mass spectrometric analysis, and Lan N’Guyen and Mélanie Crouzard for technical assistance. We thank KU Leuven (GOA, IDO), FWO (Vlaanderen) and Genoscope (Genopole, Evry) for financial support (ATIGE, EA 4527, UPS 3509). The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007‐2013)/ERC Grant agreement n° ERC‐2012‐ADG_20120216/320683. XNA=xenobiotic nucleic acids.
Abstract
Erbinformation , die in zwei Basen codiert ist, kann in Form von Cyclohexenylnucleinsäure (CeNA), Arabinofuranosylnucleinsäure (AraNA) und Hexitolnucleinsäure (HNA) in vivo in DNA übertragen werden. Demnach kann eine binäre genetische Kassette für das Titelverfahren genutzt werden.
Citing Literature
Number of times cited according to CrossRef: 11
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