[HTML][HTML] Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine

LR Baden, HM El Sahly, B Essink… - New England journal …, 2021 - Mass Medical Soc
Background Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to
protect persons who are at high risk for complications. The mRNA-1273 vaccine is a lipid
nanoparticle–encapsulated mRNA-based vaccine that encodes the prefusion stabilized full-
length spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the virus that causes Covid-19. Methods This phase 3 randomized, observer-blinded,
placebo-controlled trial was conducted at 99 centers across the United States. Persons at …