Principles of Nucleic Acid StructureNew textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976. |
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A-DNA A-RNA Acta adenine adenosine amino acid amino group anti anticodon atoms B-DNA backbone base stacking base-pairs binding Biochem Biol C-endo puckering C₁ C₂ calculated Chapter Chem cleotides complex conformation coordination crystal structure crystallographic cytosine dimer dinucleoside display distance double helix double-helical duplex dyad electron endo fiber diffraction Figure furanose geometry glycosyl guanine guanosine helical helix axis histone Hoogsteen hydration hydrogen bonds indicated interactions intercalation kcal/mole keto left-handed loop major groove metal ions molecular structure nucleic acids nucleosome nucleotides observed occur oligonucleotides orientation oxygen parameters phase angle phosphate phosphate groups planar poly(A polynucleotide polynucleotide chains protein proton pseudorotation purine pyrimidine quantum chemical residues ribose right-handed ring rotation sc range sequence side chains spectroscopic stabilized steric studies substituents sugar puckering modes supercoiled symmetry Table tion torsion angles tRNA twist unit cell uracil water molecules Watson-Crick X-ray fiber Z-DNA